Zobrazeno 1 - 10
of 1 039
pro vyhledávání: '"Jeffrey L Cummings"'
Autor:
Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern, for the DIAGNOSE CTE Research Project Investigators
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Background Traumatic encephalopathy syndrome (TES) is defined as the clinical manifestation of the neuropathological entity chronic traumatic encephalopathy (CTE). A core feature of TES is neurobehavioral dysregulation (NBD), a neuropsychiat
Externí odkaz:
https://doaj.org/article/f3d33d808dd64b46a6509a1e9d38248a
Autor:
Zhengshi Yang, Karthik Sreenivasan, Erin N. Toledano Strom, Amanda M. Leisgang Osse, Lorenzo Gabriel Pasia, Celica Glenn Cosme, Maya Rae N. Mugosa, Emma Léa Chevalier, Aaron Ritter, Justin B. Miller, Dietmar Cordes, Jeffrey L. Cummings, Jefferson W. Kinney
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Introduction There is a tremendous need for identifying reliable blood-based biomarkers for Alzheimer’s disease (AD) that are tied to the biological ATN (amyloid, tau and neurodegeneration) framework as well as clinical assessment and prog
Externí odkaz:
https://doaj.org/article/da549291807d41839da064cddc0ef4d5
Autor:
Robert A. Stern, Diana Trujillo-Rodriguez, Yorghos Tripodis, Surya V. Pulukuri, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Charles Bernick, Zachary Baucom, Kenneth L. Marek, Michael D. McClean, Keith A. Johnson, Ann C. McKee, Thor D. Stein, Jesse Mez, Joseph N. Palmisano, Jeffrey L. Cummings, Martha E. Shenton, Eric M. Reiman, for the DIAGNOSE CTE Research Project Investigators
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Exposure to repetitive head impacts (RHI) in American football players can lead to cognitive impairment and dementia due to neurodegenerative disease, particularly chronic traumatic encephalopathy (CTE). The pathognomonic lesion o
Externí odkaz:
https://doaj.org/article/c3bdde97fa634c768c7e8fc5839a2456
Autor:
Jeffrey L. Cummings, M. Isabel Gonzalez, Martyn C. Pritchard, Patrick C. May, Leticia M. Toledo-Sherman, Glenn A. Harris
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Tauopathies are a group of neurodegenerative disorders characterized by the aggregation of the microtubule-associated protein tau. Aggregates of misfolded tau protein are believed to be implicated in neuronal death, which leads to a range of
Externí odkaz:
https://doaj.org/article/de50d6618bc640deb5ed849724660489
For nearly 30 years, the Concise Guide to Neuropsychiatry and Behavioral Neurology has been an indispensable companion for clinicians caring for patients struggling with everything from delusions and hallucinations to aphasia and stroke.This third ed
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Neuropsychiatric symptoms due to Alzheimer’s disease (AD) and mild cognitive impairment (MCI) can decrease quality of life for patients and increase caregiver burden. Better characterization of neuropsychiatric symptoms and meth
Externí odkaz:
https://doaj.org/article/f4787ae87bd64268ac0a7a90c03df4eb
Autor:
Carla Abdelnour, Maria Camila Gonzalez, Lucy L. Gibson, Kathleen L. Poston, Clive G. Ballard, Jeffrey L. Cummings, Dag Aarsland
Publikováno v:
Neurology and Therapy, Vol 12, Iss 3, Pp 727-749 (2023)
Abstract Introduction Reviews of randomized clinical trials (RCTs) in dementia with Lewy bodies (DLB) are essential for informing ongoing research efforts of symptomatic therapies and potentially disease-modifying therapies (DMTs). Methods We perform
Externí odkaz:
https://doaj.org/article/1098fd9019dd4ba8a04039d27687ce28
Autor:
Davis Cammann, Yimei Lu, Melika J. Cummings, Mark L. Zhang, Joan Manuel Cue, Jenifer Do, Jeffrey Ebersole, Xiangning Chen, Edwin C. Oh, Jeffrey L. Cummings, Jingchun Chen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract A growing body of evidence suggests that dysbiosis of the human gut microbiota is associated with neurodegenerative diseases like Alzheimer’s disease (AD) via neuroinflammatory processes across the microbiota-gut-brain axis. The gut microb
Externí odkaz:
https://doaj.org/article/cf2aa3440ff0428cb92fe6491c96e93c
Autor:
Michael L. Alosco, William B. Barr, Sarah J. Banks, Jennifer V. Wethe, Justin B. Miller, Surya Vamsi Pulukuri, Julia Culhane, Yorghos Tripodis, Charles H. Adler, Laura J. Balcer, Charles Bernick, Megan L. Mariani, Robert C. Cantu, David W. Dodick, Michael D. McClean, Rhoda Au, Jesse Mez, Robert W. Turner, Joseph N. Palmisano, Brett Martin, Kaitlin Hartlage, Jeffrey L. Cummings, Eric M. Reiman, Martha E. Shenton, Robert A. Stern, for the DIAGNOSE CTE Research Project
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background Patterns of cognitive impairment in former American football players are uncertain because objective neuropsychological data are lacking. This study characterized the neuropsychological test performance of former college and profe
Externí odkaz:
https://doaj.org/article/2279786435c145eaa9f3bad5a7a4c2e1
Autor:
Eric McDade, Jeffrey L. Cummings, Shobha Dhadda, Chad J. Swanson, Larisa Reyderman, Michio Kanekiyo, Akihiko Koyama, Michael Irizarry, Lynn D. Kramer, Randall J. Bateman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Lecanemab, a humanized IgG1 monoclonal antibody that targets soluble aggregated Aβ species (protofibrils), has demonstrated robust brain fibrillar amyloid reduction and slowing of clinical decline in early AD. The objective of th
Externí odkaz:
https://doaj.org/article/a6d9281674a5413f8b67e7a74816d854