Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jeffrey L Bose"'
Autor:
Aubrey K. G. McReynolds, Emma A. Pagella, Miranda J. Ridder, Olivia Rippee, Zachary Clark, Michaella J. Rekowski, Michele T. Pritchard, Jeffrey L. Bose
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
Staphylococcus aureus is the most common cause of skin and soft tissue infections (SSTIs) with Methicillin-Resistant S. aureus (MRSA) strains being a major contributor in both community and hospital settings. S. aureus relies on metabolic diversity a
Externí odkaz:
https://doaj.org/article/4503e3ede07e475d892788e9a3d61ec4
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42244 (2012)
The most prominent murein hydrolase of Staphylococcus aureus, AtlA, is a bifunctional enzyme that undergoes proteolytic cleavage to yield two catalytically active proteins, an amidase (AM) and a glucosaminidase (GL). Although the bifunctional nature
Externí odkaz:
https://doaj.org/article/c428779841944d05909489b46c3657a1
Autor:
Jessica N. Brandwein, Tiffany S. Sculthorpe, Miranda J. Ridder, Jeffrey L. Bose, Kelly C. Rice
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Staphylococcus aureus nitric oxide synthase (saNOS) contributes to oxidative stress resistance, antibiotic tolerance, virulence, and modulation of aerobic and nitrate-based cellular respiration. Despite its involvement in these essential pro
Externí odkaz:
https://doaj.org/article/8364a332da7c46b8b9dd6cb356c7cfd2
Autor:
Jennifer L. Endres, Sujata S. Chaudhari, Xinyan Zhang, Janani Prahlad, Shu-Qi Wang, Lily A. Foley, Sorin Luca, Jeffrey L. Bose, Vinai C. Thomas, Kenneth W. Bayles
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT The Staphylococcus aureus cidABC and lrgAB operons encode members of a well-conserved family of proteins thought to be involved in programmed cell death (PCD). Based on the structural similarities that CidA and LrgA share with bacteriophage
Externí odkaz:
https://doaj.org/article/be28907b481d4d2c83ab22a975c466e8
Autor:
Christopher A. Fenton, Qingling Tang, Daniel G. Olson, Marybeth I. Maloney, Jeffrey L. Bose, Lee R. Lynd, Aron W. Fenton
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The pyruvate kinase (PYK) isozyme from Thermoanaerobacterium saccharolyticum (TsPYK) has previously been used in metabolic engineering for improved ethanol production. This isozyme belongs to a subclass of PYK isozymes that include an extra C-domain.
Externí odkaz:
https://doaj.org/article/f5d7debbf93a40659d6c6ab26565a9b1
Autor:
David Dodds, Jeffrey L. Bose, Ming-De Deng, Gilles R. Dubé, Trudy H. Grossman, Alaina Kaiser, Kashmira Kulkarni, Roger Leger, Sara Mootien-Boyd, Azim Munivar, Julia Oh, Matthew Pestrak, Komal Rajpura, Alexander P. Tikhonov, Traci Turecek, Travis Whitfill
Publikováno v:
mSphere, Vol 5, Iss 3 (2020)
ABSTRACT Using live microbes as therapeutic candidates is a strategy that has gained traction across multiple therapeutic areas. In the skin, commensal microorganisms play a crucial role in maintaining skin barrier function, homeostasis, and cutaneou
Externí odkaz:
https://doaj.org/article/ba1d4abd99a34cf9a5fdc6d24226e084
Autor:
Rachel L. Zapf, Richard E. Wiemels, Rebecca A. Keogh, Donald L. Holzschu, Kayla M. Howell, Emily Trzeciak, Andrew R. Caillet, Kellie A. King, Samantha A. Selhorst, Michael J. Naldrett, Jeffrey L. Bose, Ronan K. Carroll
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT Small RNAs (sRNAs) remain an understudied class of regulatory molecules in bacteria in general and in Gram-positive bacteria in particular. In the major human pathogen Staphylococcus aureus, hundreds of sRNAs have been identified; however, o
Externí odkaz:
https://doaj.org/article/c89ede5aaffe46dea62094b8b9b4a529
Autor:
Jessica M Reel, Jumana Abbadi, A Jesse Bueno, Katarazyna Cizio, Richard Pippin, D Annie Doyle, Laura Mortan, Jeffrey L Bose, Maureen A Cox
Publikováno v:
The Journal of Infectious Diseases.
Lymph nodes and spleens are innervated by sympathetic nerve fibers that enter alongside arteries. Despite discovery of these nerve fibers nearly 40 years ago, the role of these nerves during response to infection remains poorly defined. We have found
Autor:
Paul Briaud, Rachel L. Zapf, Ariana D. Mayher, Aubrey K. G. McReynolds, Andrew Frey, Emily G. Sudnick, Richard E. Wiemels, Rebecca A. Keogh, Lindsey N. Shaw, Jeffrey L. Bose, Ronan K. Carroll
Publikováno v:
Infect Immun
Previously, our group demonstrated a role for the small RNA (sRNA) Teg41 in regulating production of the alpha phenol-soluble modulin toxins (αPSMs) in Staphylococcus aureus. Overexpressing Teg41 increased αPSM production while deleting the 3′ en
Autor:
Miranda J. Ridder, Aubrey K.G. McReynolds, Hongyan Dai, Michele T. Pritchard, Mary A. Markiewicz, Jeffrey L. Bose
Publikováno v:
Infect Immun
Staphylococcus aureus is a leading cause of skin and soft tissue infections (SSTIs). Studies examining the immune response to S. aureus have been conducted, yet our understanding of the kinetic response to S. aureus subcutaneous skin infection remain