Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Jeffrey L, Garvin"'
Autor:
Autumn Brostek, Nancy J. Hong, Ronghao Zhang, Beau R. Forester, Lauren E. Barmore, Lindsey Kaydo, Nicholas Kluge, Corey Smith, Jeffrey L. Garvin, Agustin Gonzalez‐Vicente
Publikováno v:
Physiological Reports, Vol 10, Iss 19, Pp n/a-n/a (2022)
Abstract Proximal tubule fructose metabolism is key to fructose‐induced hypertension, but the roles of sex and stress are unclear. We hypothesized that females are resistant to the salt‐sensitive hypertension caused by low amounts of dietary fruc
Externí odkaz:
https://doaj.org/article/ce6b04dce8884acba616e8aa7eef342c
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201293 (2018)
Fructose consumption causes metabolic diseases and renal injury primarily in the renal cortex where fructose is metabolized. Analyzing gene differential expression induced by dietary manipulation is challenging. The effects may depend on the base die
Externí odkaz:
https://doaj.org/article/76e551a93f724007a21ffd0ba32d5de7
Publikováno v:
Am J Physiol Renal Physiol
Angiotensin II (ANG II) stimulates proximal nephron transport via activation of classical protein kinase C (PKC) isoforms. Acute fructose treatment stimulates PKC and dietary fructose enhances ANG II’s ability to stimulate Na+transport, but the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e426bafc43cbac880e588d627bdfce6
https://doi.org/10.1152/ajprenal.00543.2019
https://doi.org/10.1152/ajprenal.00543.2019
Publikováno v:
Am J Physiol Renal Physiol
Angiotensin II exacerbates oxidative stress in part by increasing superoxide ([Formula: see text]) production by many renal tissues. However, whether it does so in proximal tubules and the source of [Formula: see text] in this segment are unknown. Di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8493bbf647314afc2ca13f804bdd116
https://doi.org/10.1152/ajprenal.00462.2019
https://doi.org/10.1152/ajprenal.00462.2019
Publikováno v:
Am J Physiol Renal Physiol
Claudins are a family of tight junction proteins that provide size and charge selectivity to solutes traversing the paracellular space. Thick ascending limbs (TALs) express numerous claudins, including claudin-19. Nitric oxide (NO), via cGMP, reduces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6b9cc0497b20a30831eccf33b44d35
https://doi.org/10.1152/ajprenal.00065.2019
https://doi.org/10.1152/ajprenal.00065.2019
Autor:
Jessica Asirwatham, Nancy J. Hong, Fara Saez, Jeffrey L. Garvin, Pablo D. Cabral, Agustin Gonzalez-Vicente
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F473-F480
Fructose consumption has increased because of widespread use of high-fructose corn syrup by the food industry. Renal proximal tubules are thought to reabsorb fructose. However, fructose reabsorption (Jfructose) by proximal tubules has not yet been di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5287cc5c5840614dab1026e98ea75f57
https://doi.org/10.1152/ajprenal.00247.2018
https://doi.org/10.1152/ajprenal.00247.2018
Publikováno v:
Am J Physiol Renal Physiol
Dahl salt-sensitive (SS) rat kidneys produce less nitric oxide (NO) than those of salt-resistant (SR) rats. Thick ascending limb (TAL) NO synthase 3 (NOS3) is a major source of renal NO, and luminal flow enhances its activity. We hypothesized that fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049c02e78976939540bfce89b98a5ecf
https://europepmc.org/articles/PMC8530749/
https://europepmc.org/articles/PMC8530749/
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110487 (2014)
The thick ascending limb of the loop of Henle reabsorbs 30% of the NaCl filtered through the glomerulus. Nitric oxide (NO) produced by NO synthase 3 (NOS3) inhibits NaCl absorption by this segment. Resveratrol, a polyphenol, has beneficial cardiovasc
Externí odkaz:
https://doaj.org/article/dd0cce2402e941068ddc677096d9cd9d
Autor:
William, Ye, Jill, Patel, Katrina, Thede, Varsha, Aravindabose, Simon, Wentworth, Ian, Monroe, Matthew L, Garvin, Jeffrey L, Garvin, Randall K, Packer
Publikováno v:
Comparative biochemistry and physiology. Part A, Molecularintegrative physiology. 257
Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abf5491dc625e5ac5f519073b8ba57f6
https://pubmed.ncbi.nlm.nih.gov/33974967
https://pubmed.ncbi.nlm.nih.gov/33974967
Autor:
Jeffrey L. Garvin, Fara Saez, Jessica Asirwatham, Agustin Gonzalez-Vicente, Casandra Margarita Monzón
Publikováno v:
Physiological Reviews. 99:235-309
The thick ascending limb plays a key role in maintaining water and electrolyte balance. The importance of this segment in regulating blood pressure is evidenced by the effect of loop diuretics or local genetic defects on this parameter. Hormones and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415060753992f6db601c827d99ef5f2b
https://doi.org/10.1152/physrev.00055.2017
https://doi.org/10.1152/physrev.00055.2017