Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Jeffrey L, Ebersole"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract We used a nonhuman primate model of ligature-induced periodontitis to identify patterns of gingival transcriptomic after changes demarcating phases of periodontitis lesions (initiation, progression, resolution). A total of 18 adult Macaca mu
Externí odkaz:
https://doaj.org/article/48c76a8884504a86b2dcc36917ce6dcb
Comparative Analysis of Gene Expression Patterns for Oral Epithelial Cell Functions in Periodontitis
Autor:
Octavio A. Gonzalez, Sreenatha Kirakodu, Linh M. Nguyen, Luis Orraca, Michael J. Novak, Janis Gonzalez-Martinez, Jeffrey L. Ebersole
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants
Externí odkaz:
https://doaj.org/article/93da86d21d604aef9de58fcb9d2920de
Publikováno v:
Frontiers in Oral Health, Vol 3 (2022)
The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environmen
Externí odkaz:
https://doaj.org/article/737a36655254471a908885ec3f84c2d1
Autor:
Jeffrey L Ebersole, Octavio A Gonzalez
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0275199 (2022)
As circadian processes can impact the immune system and are affected by infections and inflammation, this study examined the expression of circadian rhythm genes in periodontitis.MethodsMacaca mulatta were used with naturally-occurring and ligature-i
Externí odkaz:
https://doaj.org/article/2c13b69c979f469791d40d1ab70dc272
Publikováno v:
Frontiers in Oral Health, Vol 2 (2021)
Although data describe the presence and increase of inflammatory mediators in the local environment in periodontitis vs. health in humans, details regarding how these responses evolve in the transition from health to disease, changes during disease p
Externí odkaz:
https://doaj.org/article/9d63d8f8a13e46cb88f5f14b32ff7004
Publikováno v:
Journal of Periodontal Research. 58:493-502
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::473f3d289fd231d02ad5d11b24eeaefe
https://doi.org/10.1111/jre.13127
https://doi.org/10.1111/jre.13127
Publikováno v:
Clinical and Experimental Immunology. 211:248-268
Phenotypic and functional heterogeneity of macrophages is clearly a critical component of their effective functions in innate and adaptive immunity. This investigation hypothesized that altered profiles of gene expression in gingival tissues in healt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb63adfcbdcc28eaf4a894108ebd362
https://doi.org/10.1093/cei/uxac122
https://doi.org/10.1093/cei/uxac122
Autor:
Jeffrey L. Ebersole, Sreenatha S. Kirakodu, Elliot Neumann, Luis Orraca, Janis Gonzalez Martinez, Octavio A. Gonzalez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Objective: This study focused on documenting characteristics of the gingival transcriptome during various stages of periodontitis targeting genes associated with apoptotic and autophagic pathways and changes that specifically associate with features
Externí odkaz:
https://doaj.org/article/7a2588aa159b448fb5eb514ae346991e
Publikováno v:
Molecular Oral Microbiology. 38:93-114
Rhesus monkeys (n = 36) exhibiting a healthy periodontium at baseline were used to induce progressing periodontitis through ligature placement around premolar/molar teeth. Bacterial samples were collected at baseline, 0.5, 1, and 3 months of disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b51efa69c43b2833ce7531e397a85a1
https://doi.org/10.1111/omi.12377
https://doi.org/10.1111/omi.12377
Publikováno v:
Antioxidants, Vol 10, Iss 11, p 1730 (2021)
Strawberries, a popularly consumed berry fruit, are rich in bioactive compounds with antioxidant effects. In this study, we examined the effects of two dietary achievable doses of strawberries on the antioxidant status and biomarkers of endothelial f
Externí odkaz:
https://doaj.org/article/2faa960191c64d37b73cfaf3be5a7266