Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jeffrey K. Beetham"'
Publikováno v:
Molecular and Biochemical Parasitology. 193:66-70
Nematode anthelminthic resistance is widespread for the 3 major drug classes commonly used in agriculture: benzamidazoles, macrocyclic lactones, and nicotinic agonists e.g. levamisole. In parasitic nematodes the genetics of resistance are unknown oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965359854b522ad071a7472135c61d6d
https://doi.org/10.1016/j.molbiopara.2014.02.002
https://doi.org/10.1016/j.molbiopara.2014.02.002
Publikováno v:
Journal of Parasitology. 98:1109-1116
Previous works demonstrated that various species of Leishmania promastigotes exhibit differential sensitivity to complement-mediated lysis (CML) during development. Upon exposure to normal human serum (NHS), cultures of Leishmania chagasi promastigot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebf238e228eb4190e46c88048c470a0
https://doi.org/10.1645/ge-3130.1
https://doi.org/10.1645/ge-3130.1
Publikováno v:
Journal of Parasitology. 96:1134-1138
Leishmania chagasi causes visceral leishmaniasis, a potentially fatal disease of humans. Within the sand fly vector, L. chagasi replicates as promastigotes which undergo complex changes in morphology as they progress from early stage procyclic promas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3af8d2e92230a6c7acf2a7862341cd8
https://doi.org/10.1645/ge-2566.1
https://doi.org/10.1645/ge-2566.1
Publikováno v:
Journal of Parasitology. 91:1058-1063
Past studies showed that Leishmania spp. promastigotes exhibit differential sensitivity to complement mediated lysis (CML) during development in vitro and in vivo. Leishmania chagasi promastigotes in cultures during logarithmic and stationary growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380d84457d318309bd186d4dbbb66ecd
https://doi.org/10.1645/ge-477r.1
https://doi.org/10.1645/ge-477r.1
Surface glycoprotein PSA (GP46) expression during short- and long-term culture of Leishmania chagasi
Publikováno v:
Molecular and Biochemical Parasitology. 131:109-117
The mRNAs encoding promastigote surface antigen (PSA) of Leishmania chagasi have previously been shown to increase about 30-fold as in vitro cultured parasites progress from logarithmic to stationary phase, growth phases that are, respectively associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac87ee13d9a82c452c96ebde95f89c6
https://doi.org/10.1016/s0166-6851(03)00197-x
https://doi.org/10.1016/s0166-6851(03)00197-x
Publikováno v:
Journal of Biological Chemistry. 277:16489-16497
MSP (GP63) and PSA (GP46) are abundant 63- and 46-kDa glycolipid-anchored proteins on the surface of the promastigote form of most Leishmania species. MSP is a zinc metalloprotease that confers resistance to host complement-mediated lysis. PSA contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9ef03b5bfdfcc9bb60599d8199fd3f
https://doi.org/10.1074/jbc.m200174200
https://doi.org/10.1074/jbc.m200174200
Publikováno v:
BMC Genetics
Background Gene identification and sequence determination are critical requirements for many biological, genomic, and bioinformatic studies. With the advent of next generation sequencing (NGS) technologies, such determinations are predominantly accom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924f420938cc8dc716208bf0417193c0
https://doi.org/10.1186/1471-2156-14-55
https://doi.org/10.1186/1471-2156-14-55
Biochemical Characterization of the Human Liver Cytochrome P450 Arachidonic Acid Epoxygenase Pathway
Autor:
Nate Jesse, Cindy R. Moomaw, Kenneth B. Tomer, Bruce D. Hammock, Shu Wu, Jeffrey K. Beetham, Darryl C. Zeldin
Publikováno v:
Archives of Biochemistry and Biophysics. 330:87-96
Human liver microsomal fractions metabolized arachidonic acid in the presence of NADPH yielding epoxyeicosatrienoic acids and their hydration products, dihydroxyeicosatrienoic acids, as the principal reaction products. Inhibition studies using polycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2ec7d2690ceef83e1e36fc5f0fb7fc
https://doi.org/10.1006/abbi.1996.0229
https://doi.org/10.1006/abbi.1996.0229
Autor:
Steve Landt, Jeffrey K. Beetham, Anthony G. Parker, Bruce D. Hammock, Franck Pinot, David F. Grant, Babak Borhan, Arthur D. Jones
Publikováno v:
Journal of Biological Chemistry. 270:7968-7974
In order to investigate the involvement of amino acids in the catalytic mechanism of the soluble epoxide hydrolase, different mutants of the murine enzyme were produced using the baculovirus expression system. Our results are consistent with the invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a1e1c18453f52f24558863ed52c9ae
https://doi.org/10.1074/jbc.270.14.7968
https://doi.org/10.1074/jbc.270.14.7968
Autor:
Bruce D. Hammock, Franz Oesch, Tomohiro Kiyosue, David F. Grant, Kazuo Shinozaki, Joan Garbarino, Jeffrey K. Beetham, William R. Belknap, Michael Arand, Franck Pinot
Publikováno v:
DNA and Cell Biology. 14:61-71
We have analyzed amino acid sequence relationships among soluble and microsomal epoxide hydrolases, haloacid dehalogenases, and a haloalkane dehalogenase. The amino-terminal residues (1-229) of mammalian soluble epoxide hydrolase are homologous to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c9600e2ebece7baea464ebdcb970d1
https://doi.org/10.1089/dna.1995.14.61
https://doi.org/10.1089/dna.1995.14.61