Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jeffrey K. Bailey"'
Autor:
Dimitrios Pollalis, Gopa Kumar Gopinadhan Nair, Justin Leung, Clarisa Marie Bloemhof, Jeffrey K. Bailey, Britney O. Pennington, Kaitlin R. Kelly, Amir I. Khan, Ashley K. Yeh, Kartik S. Sundaram, Dennis O. Clegg, Chen‐Ching Peng, Liya Xu, Constantin Georgescu, Jonathan D. Wren, Sun Young Lee
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract Retinal pigment epithelial (RPE) cells are exclusive to the retina, critically multifunctional in maintaining the visual functions and health of photoreceptors and the retina. Despite their vital functions throughout lifetime, RPE cells lack
Externí odkaz:
https://doaj.org/article/4be1ebe138c34e68b67d9407d4963b56
Publikováno v:
Cells, Vol 13, Iss 14, p 1189 (2024)
The chromatin-associated protein WDR5 has been widely studied due to its role in histone modification and its potential as a pharmacological target for the treatment of cancer. In humans, the protein with highest sequence homology to WDR5 is encoded
Externí odkaz:
https://doaj.org/article/6309beec5d584e77ac0f4396319fefb4
Autor:
Britney O. Pennington, Jeffrey K. Bailey, Mohamed A. Faynus, Cassidy Hinman, Mitchell N. Hee, Rory Ritts, Vignesh Nadar, Danhong Zhu, Debbie Mitra, Juan Carlos Martinez-Camarillo, Tai-Chi Lin, Biju B. Thomas, David R. Hinton, Mark S. Humayun, Jane Lebkowski, Lincoln V. Johnson, Dennis O. Clegg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Age-related macular degeneration (AMD) is the primary cause of blindness in adults over 60 years of age, and clinical trials are currently assessing the therapeutic potential of retinal pigmented epithelial (RPE) cell monolayers on implantab
Externí odkaz:
https://doaj.org/article/f19a0c25861141a083ed1e359e044d22
Autor:
Mohamed A. Faynus, Jeffrey K. Bailey, Britney O. Pennington, Mika Katsura, Duncan A. Proctor, Ashley K. Yeh, Sneha Menon, Dylan G. Choi, Jane S. Lebkowski, Lincoln V. Johnson, Dennis O. Clegg
Publikováno v:
Bioengineering, Vol 9, Iss 7, p 297 (2022)
Dry age-related macular degeneration (AMD) is estimated to impact nearly 300 million individuals globally by 2040. While no treatment options are currently available, multiple clinical trials investigating retinal pigmented epithelial cells derived f
Externí odkaz:
https://doaj.org/article/5f35764a0d304571b157eef32c3eac10
Autor:
Vignesh P. Nadar, Lincoln V. Johnson, Mark S. Humayun, Dennis O. Clegg, Rory Ritts, Juan Carlos Martinez-Camarillo, Debbie Mitra, Tai-Chi Lin, David R. Hinton, Danhong Zhu, Mitchell N Hee, Cassidy R. Hinman, Britney O Pennington, Biju B. Thomas, Jeffrey K Bailey, Jane Lebkowski, Mohamed A Faynus
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Age-related macular degeneration (AMD) is the primary cause of blindness in adults over 60 years of age, and clinical trials are currently assessing the therapeutic potential of retinal pigmented epithelial (RPE) cell monolayers on implantable scaffo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da70d49da2a1cbef2201561f0a53adbb
https://pubmed.ncbi.nlm.nih.gov/33737600
https://pubmed.ncbi.nlm.nih.gov/33737600
Autor:
Debbie Mitra, Sanford Chen, Hani Salehi-Had, April Ingram, Chih-Min Lin, Mohamed A Faynus, Lincoln V. Johnson, Mark S. Humayun, Amir H. Kashani, Narsing A. Rao, Jane Lebkowski, Clement Chan, Dennis O. Clegg, Robert L. Avery, Jeffrey K Bailey, Neal V. Palejwala, Cassidy R. Hinman, Sukriti Mohan, David R. Hinton, Wei Dang, Firas M. Rahhal, Britney O Pennington
Publikováno v:
Translational Vision Science & Technology
Purpose To report 1-year follow-up of a phase 1/2a clinical trial testing a composite subretinal implant having polarized human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells on an ultrathin parylene substrate in subjects w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c59c05560850894233eba1a8aeca28
https://doi.org/10.1167/tvst.10.10.13
https://doi.org/10.1167/tvst.10.10.13
Publikováno v:
Nucleic Acids Research
Antisense oligonucleotides (ASOs) are versatile tools that can regulate multiple steps of RNA biogenesis in cells and living organisms. Significant improvements in delivery, potency, and stability have been achieved through modifications within the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd2a8937fd908b4922e659a71d94c40
https://doi.org/10.1093/nar/gkx709
https://doi.org/10.1093/nar/gkx709
Autor:
Dzwokai Ma, Jeffrey K Bailey
Publikováno v:
Frontiers in Biology. 11:10-18
The MLL/SET family of histone H3 lysine 4 methyltransferases form enzyme complexes with core subunits ASH2L, WDR5, RbBP5, and DPY-30 (often abbreviated WRAD), and are responsible for global histone H3 lysine 4 methylation, a hallmark of actively tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c1c0466c1c5e89c3911440455b41628
https://doi.org/10.1007/s11515-016-1390-6
https://doi.org/10.1007/s11515-016-1390-6
Publikováno v:
Nucleic Acids Research
An R-loop is a DNA:RNA hybrid formed during transcription when a DNA duplex is invaded by a nascent RNA transcript. R-loops accumulate in nucleoli during RNA polymerase I (RNAP I) transcription. Here, we report that mammalian RNase H1 enriches in nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d3986bb274449274e6a3efcfa0fea7
https://pubmed.ncbi.nlm.nih.gov/28977560
https://pubmed.ncbi.nlm.nih.gov/28977560
Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization
Publikováno v:
Addiction Biology. 17:248-258
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that controls global protein synthesis, in part, by modulating translation initiation, a rate-limiting step for many mRNAs. Previous studies implicate mTOR in regulating stimulant-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba1a0bad5448cc72de3256c16931f737
https://doi.org/10.1111/j.1369-1600.2010.00311.x
https://doi.org/10.1111/j.1369-1600.2010.00311.x