Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jeffrey J. Yourick"'
Publikováno v:
Data in Brief, Vol 43, Iss , Pp 108477- (2022)
A variety of methods have been reported for the differentiation of hepatocyte-like cells (HLCs) from human induced pluripotent stem cells (iPSCs) using various growth factors or small molecules. However, direct comparison of the differentiation effic
Externí odkaz:
https://doaj.org/article/b0e2bb96cef748b19502b9342df535ef
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-21 (2020)
Abstract Background Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have mostl
Externí odkaz:
https://doaj.org/article/050a29d497e046bcbda45ab772adde80
Publikováno v:
Stem Cell Research, Vol 31, Iss , Pp 193-196 (2018)
Human induced pluripotent stem cells (iPSCs) provide a potentially unlimited source of differentiated cells from individuals with specific genetic backgrounds. Using self-replicative RNA reprogramming technology, we generated nine iPSC lines from end
Externí odkaz:
https://doaj.org/article/f2e24709b3924e8e899f22c81b51f872
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 202-212 (2017)
Induced pluripotent stem cells (iPSCs) offer the potential to generate tissues with ethnic diversity enabling toxicity testing on selected populations. Recently, it has been reported that endothelial progenitor cells (EPCs) derived from umbilical cor
Externí odkaz:
https://doaj.org/article/070dfd9026714604b164ec5cfa6a8dad
Publikováno v:
Journal of Nanobiotechnology, Vol 15, Iss 1, Pp 1-18 (2017)
Abstract Background The widespread application of silver nanoparticles (AgNPs) and silver-containing products has raised public safety concerns about their adverse effects on human health and the environment. To date, in vitro toxic effects of AgNPs
Externí odkaz:
https://doaj.org/article/bb739312933941c8b634d7e0f168b4f3
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 199-202 (2015)
Thalidomide is a potent developmental toxicant that induces a range of birth defects, notably severe limb malformations. To unravel the molecular mechanisms underpinning the teratogenic effects of thalidomide, we used microarrays to study transcripto
Externí odkaz:
https://doaj.org/article/a5223b42d0b349e5ba295d7447ecea67
Autor:
Xiugong Gao, Jeffrey J. Yourick, Vanessa D. Topping, Thomas Black, Nicholas Olejnik, Zachary Keltner, Robert L. Sprando
Publikováno v:
Toxicology Reports, Vol 2, Iss C, Pp 341-350 (2015)
Male and female rats (26-day-old) were exposed to 0.0, 0.4, 4 or 40 mg/kg body weight silver acetate (AgAc) in drinking water for 10 weeks prior to and during mating. Sperm-positive females remained within their dose groups and were exposed to silver
Externí odkaz:
https://doaj.org/article/2459165f51d94ae99d21b707678fba84
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2429
Human induced pluripotent stem cells (iPSCs) hold great promise for biomedical applications. However, establishment of new iPSC lines still presents many challenges. Here we describe a simple yet highly efficient two-step protocol for the isolation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::522720e93c242964701240131934b797
https://pubmed.ncbi.nlm.nih.gov/35507151
https://pubmed.ncbi.nlm.nih.gov/35507151
Publikováno v:
Biomedical Reports. 16
Directed differentiation of human induced pluripotent stem cells (iPSCs) into hepatocytes could provide an unlimited source of liver cells, and therefore holds great promise for regenerative medicine, disease modeling, drug screening and toxicology s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b340ca68f3844f9130be42f0441cfa2f
https://doi.org/10.3892/br.2022.1526
https://doi.org/10.3892/br.2022.1526
Publikováno v:
Cell Biology and Toxicology. 37:245-259
The application of silver nanoparticles (AgNPs) in consumer products has been increasing rapidly over the past decades. Therefore, in vitro models capable of accurately predicting the toxicity of AgNPs are much needed. Hepatocyte-like cells (HLCs) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d858b23d2c6bb6f721a19997c241e7
https://doi.org/10.1007/s10565-020-09529-1
https://doi.org/10.1007/s10565-020-09529-1