Bone morphogenetic protein-9 binds to liver cells and stimulates proliferation

Autor: A. J. Celeste, Randy L. Jirtle, Vicki Rosen, Feng Ming Kong, R S Thies, Jeffrey J. Song

Publikováno v: Endocrinology. 136:4293-4297

A new member of the transforming growth factor (TGF)-beta superfamily, BMP-9, has recently been identified and shown to be expressed in the developing mouse liver. This report demonstrates that human HepG2 liver tumor cells bind recombinant human BMP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a5c2334fc7a582b08ab79ec2e925d1
https://doi.org/10.1210/endo.136.10.7664647

Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway

Autor: Alan J. Bitonti, Ana Maria Garcia, Cristina A. Tan, Wayne I. Lencer, Jeffrey J. Song, James M. Stattel, Richard S. Blumberg, Keith E. Kropp, Robert T. Peters, Gerburg M. Spiekermann, Vito J. Palombella, Susan C. Low, Neil E. Simister, Jennifer A. Dumont, Yichun Lu

Administration of therapeutic proteins by methods other than injection is limited, in part, by inefficient penetration of epithelial barriers. Therefore, unique approaches to breaching these barriers are needed. The neonatal constant region fragment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dd5f50aa3af6830620c2b511989073
https://europepmc.org/articles/PMC470748/

Prostate Cancer Therapy Cardiotoxicity Map (PROXMAP) for Advanced Disease States: A Systematic Review and Network Meta-analysis with Bayesian Modeling of Treatment Histories.

Autor: Aziz MK; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Molony D; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Monlezun D; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Holder T; Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Brunckhorst O; MRC Centre for Transplantation, Guy's Hospital Campus, King's College London, King's Health Partners, London, UK., Higgason N; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Roland J; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Magill R; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Fatakdawala M; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Iacobucci A; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Mody-Bailey N; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Owen C; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Zarker A; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Thames E; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Swaby J; Department of Internal Medicine, University of Georgia, Augusta, GA, USA., Xiao D; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Choi L; Department of Internal Medicine, University of the Incarnate Word, San Antonio, TX, USA., Desai S; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Galan J; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Deng B; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Hartshorne T; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Nichols A; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Zhang A; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Imber J; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Song J; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Jones W; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Rivas A; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Sanchez D; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Guhan M; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., Gandaglia G; Department of Urology, San Raffaele Hospital, Milan, Italy., Ranganath S; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Jacob J; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Howell S; McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA., Plana J; Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA., van den Bergh R; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Roberts M; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Sommer SG; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Oldenburg J; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Ploussard G; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Tilki D; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Schoots I; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Briers E; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Stranne J; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Rouviere O; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., van Oort I; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Oprea-Lager D; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., De Santis M; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands., Cornford P; Prostate Cancer Guidelines Panel, European Association of Urology, Arnhem, The Netherlands.

Publikováno v: European urology [Eur Urol] 2024 Sep 18. Date of Electronic Publication: 2024 Sep 18.

A missense mutation in SLC6A1 associated with Lennox-Gastaut syndrome impairs GABA transporter 1 protein trafficking and function.

Autor: Cai K; Department of Neurology, Vanderbilt University Medical Center, TN 37232, USA; Department of Neurology, Affiliated Hospital, Nantong University, Nantong, Jiangsu 226001, China., Wang J; Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China., Eissman J; Department of Neurology, Vanderbilt University Medical Center, TN 37232, USA., Wang J; Department of Electrical Engineering & Computer Science and Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA., Nwosu G; Neuroscience Graduate Program, Vanderbilt-Meharry Alliance, Vanderbilt University, TN 37235, USA., Shen W; Department of Neurology, Vanderbilt University Medical Center, TN 37232, USA., Liang HC; Guangzhou Women and Children's Medical Center Guangzhou Children's Hospital, Guangzhou, China., Li XJ; Guangzhou Women and Children's Medical Center Guangzhou Children's Hospital, Guangzhou, China., Zhu HX; Guangzhou Women and Children's Medical Center Guangzhou Children's Hospital, Guangzhou, China., Yi YH; Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China., Song J; Department of Neurology, Vanderbilt University Medical Center, TN 37232, USA., Xu D; Department of Electrical Engineering & Computer Science and Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA., Delpire E; Department of Anesthesiology, Vanderbilt University Department of Anesthesiology, Vanderbilt University, Nashville, TN 37232, USA., Liao WP; Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China., Shi YW; Institute of Neuroscience and Department of Neurology of the Second Affiliated Hospital of Guangzhou Medical University, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou 510260, China. Electronic address: stoneyiwu@163.com., Kang JQ; Department of Neurology, Vanderbilt University Medical Center, TN 37232, USA. Electronic address: Jingqiong.kang@vanderbilt.edu.

Publikováno v: Experimental neurology [Exp Neurol] 2019 Oct; Vol. 320, pp. 112973. Date of Electronic Publication: 2019 Jun 06.

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.

Autor: Knutson SK; Epizyme, Inc., Cambridge, MA, USA., Wigle TJ, Warholic NM, Sneeringer CJ, Allain CJ, Klaus CR, Sacks JD, Raimondi A, Majer CR, Song J, Scott MP, Jin L, Smith JJ, Olhava EJ, Chesworth R, Moyer MP, Richon VM, Copeland RA, Keilhack H, Pollock RM, Kuntz KW

Publikováno v: Nature chemical biology [Nat Chem Biol] 2012 Nov; Vol. 8 (11), pp. 890-6. Date of Electronic Publication: 2012 Sep 30.