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pro vyhledávání: '"Jeffrey J. Seidel"'
Autor:
Elizabeth H. Blackburn, Carol M. Anderson, Dana L. Smith, Andrej Sali, Dmitry Korkin, Jeffrey J. Seidel, Svetlana Makovets
Publikováno v:
Anderson, C M, Korkin, D, Smith, D L, Makovets, S, Seidel, J J, Sali, A & Blackburn, E H 2008, ' Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break ', Genes & Development, vol. 22, no. 7, pp. 854-859 . https://doi.org/10.1101/gad.1646208
The kinases ATM and ATR (Tel1 and Mec1 in the yeast Saccharomyces cerevisiae) control the response to DNA damage. We report that S. cerevisiae Tel2 acts at an early step of the TEL1/ATM pathway of DNA damage signaling. We show that Tel1 and Tel2 inte
Autor:
Barbara J. Graves, Jeffrey J. Seidel
Publikováno v:
Genes & Development. 16:127-137
The ETS transcription factors perform distinct biological functions despite conserving a highly similar DNA-binding domain. One distinguishing property of a subset of ETS proteins is a conserved region of 80 amino acids termed the Pointed (PNT) domai
Autor:
Cameron D. Mackereth, Lawrence P. McIntosh, Barbara J. Graves, Lisa Gentile, Jeffrey J. Seidel, Carolyn M. Slupsky, Logan W. Donaldson
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12129-12134
The Pointed (PNT) domain and an adjacent mitogen-activated protein (MAP) kinase phosphorylation site are defined by sequence conservation among a subset of ets transcription factors and are implicated in two regulatory strategies, protein interaction
Tel1/ATM, a conserved phosphatidylinositol 3-kinase-related kinase (PIKK), acts in the response to DNA damage and regulates telomere maintenance. PIKK family members share an extended N-terminal region of low sequence homology. Sequence alignment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0585f89d0ed41f608ae43105c852ae18
https://europepmc.org/articles/PMC2546937/
https://europepmc.org/articles/PMC2546937/