Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jeffrey J. O'brian"'
Publikováno v:
Journal of Biological Chemistry. 277:37154-37160
Cardiac calsequestrin concentrates in junctional sarcoplasmic reticulum in heart and skeletal muscle cells by an undefined mechanism. During transit through the secretory pathway, it undergoes an as yet uncharacterized glycosylation and acquires phos
Publikováno v:
Circulation Research. 82:367-374
Abstract —Phospholemman (PLM) is a small (72–amino acid) transmembrane protein found in cardiac sarcolemma that is a major substrate for several protein kinases in vivo. Detailed structural data for PLM is lacking, but several studies have descri
Autor:
Gopal C. Kowdley, Jeffrey J. O'Brian, M. Pamela Griffin, J. Randall Moorman, Stephen J. Ackerman, Larry R. Jones, J. Paul Mounsey, Zhenhui Chen, Gabor Szabo, Steven E. Cala
Publikováno v:
Nature. 377:737-740
Phospholemman (PLM) is a 72-amino-acid peptide with a single transmembrane domain, the expression of which induces chloride currents in Xenopus oocytes. It has remained unknown whether PLM is an ion channel or acts as a channel regulator. Here we sho
Autor:
Jeffrey J. O'Brian, Suren A. Tatulian, Larry R. Jones, Laxma G. Reddy, David L. Stokes, Steven E. Cala
Publikováno v:
Journal of Biological Chemistry. 270:9390-9397
Phospholamban (PLB) is a small, transmembrane protein that resides in the cardiac sarcoplasmic reticulum (SR) and regulates the activity of Ca(2+)-ATPase in response to beta-adrenergic stimulation. We have used the baculovirus expression system in Sf
Autor:
Jeffrey J. O'Brian, Calvin L. Keeler, Stuart J. Rabin, David J. Poulsen, Catherine R. Adams Burton
Publikováno v:
Virus genes. 5(4)
The infectious laryngotracheitis virus (ILTV) homologue of the herpes simplex virus type 1 (HSV-1) glycoprotein B (gB) gene was identified by PCR amplification of genomic ILTV DNA. A 488-bp amplified DNA fragment was used to identify and clone two ad
Publikováno v:
The Journal of Dermatologic Surgery and Oncology. 11:714-717
Smooth muscle hamartomas are rare benign tumors of the skin, characterized by proliferation of large interlacing bundles of nonstriated muscle within the reticular dermis. The lesions may masquerade as one of several clinical entities. In this report
Autor:
C. William Hanke, Jeffrey J. O'brian
Publikováno v:
The Journal of Dermatologic Surgery and Oncology. 13:664-669
The effects of a number of commonly used skin refrigerants were studied in controlled freezing experiments on guinea pig skin. Frigiderm and Fluro Ethyl produced very little effect on the skin compared to colder preparations such as Cryosthesia -30 d
Publikováno v:
The Journal of Dermatologic Surgery and Oncology. 10:90-93
Publikováno v:
The Journal of Dermatologic Surgery and Oncology. 9:260-262
Publikováno v:
The Journal of dermatologic surgery and oncology. 9(9)
Basal-cell carcinoma with perineural invasion is a rare occurrence. Ten patients with this phenomenon are described. Review of our cases and cases in the literature indicates that perineural spread of basal-cell carcinoma is most common in men with r