Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeffrey J. Kelu"'
Publikováno v:
Contact, Vol 6 (2023)
We have previously shown that in the developing trunk of zebrafish embryos, two-pore channel type 2 (TPC2)-mediated Ca 2+ release from endolysosomes plays a role in the formation of the skeletal slow muscle. In addition, TPC2-mediated Ca 2+ signaling
Externí odkaz:
https://doaj.org/article/886f194be836482e8fa3cf994bd2c0ea
Publikováno v:
Hau, H T A, Kelu, J J, Ochala, J & Hughes, S M 2023, ' Slow myosin heavy chain 1 is required for slow myofibril and muscle fibre growth but not for myofibril initiation ', Developmental Biology, vol. 499, pp. 47-58 . https://doi.org/10.1016/j.ydbio.2023.04.002
Slow myosin heavy chain 1 (Smyhc1) is the major sarcomeric myosin driving early contraction by slow skeletal muscle fibres in zebrafish. New mutant alleles lacking a functional smyhc1 gene move poorly, but recover motility as the later-formed fast mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f19ac15f4d10a38a865cad688182a8
https://doi.org/10.1016/j.ydbio.2023.04.002
https://doi.org/10.1016/j.ydbio.2023.04.002
Publikováno v:
Journal of visualized experiments : JoVE. (184)
A number of methods can be used to visualize individual cells throughout the body of live embryonic, larval or juvenile zebrafish. We show that live fish with fluorescently-marked plasma membranes can be scanned in a confocal laser scanning microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d01f5996a370c4f658777ef9769481
https://pubmed.ncbi.nlm.nih.gov/35781279
https://pubmed.ncbi.nlm.nih.gov/35781279
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A long-standing question, particularly in physiotherapy and sports medicine, is whether time of day affects muscle metabolism and hence growth, either intrinsically or in response to exercise or nutrition. Answers would help to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfd2729673eec8fc2df7c070019b1a8
https://doi.org/10.1073/pnas.2012450117
https://doi.org/10.1073/pnas.2012450117
Publikováno v:
Developmental Biology. 445(2)
We recently demonstrated the requirement of two-pore channel type 2 (TPC2)-mediated Ca2+ release during slow muscle cell differentiation and motor circuit maturation in intact zebrafish embryos. However, the upstream trigger(s) of TPC2/Ca2+ signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebdc150417c7e9559df235ab187485c
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
Developmental Biology. 438(1)
During the development of the early spinal circuitry in zebrafish, spontaneous Ca2+ transients in the primary motor neurons (PMNs) are reported to transform from being slow and uncorrelated, to being rapid, synchronized and patterned. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76e2acff6d5f42eeba51f8f8b124ef5
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Jeffrey J. Kelu, John Parrington, Hayley L.H. Chan, Margarida Ruas, Andrew L. Miller, Arthur H.H. Cheng, Sarah E. Webb, Antony Galione
Publikováno v:
The International Journal of Developmental Biology. 59:313-325
We have recently characterized essential inositol 1,4,5-trisphosphate receptor (IP(3)R) and ryanodine receptor (RyR)-mediated Ca(2+) signals generated during the differentiation of slow muscle cells (SMCs) in intact zebrafish embryos. Here, we show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4001fa72287a33c8e8ac1e97dca1e393
https://doi.org/10.1387/ijdb.150206am
https://doi.org/10.1387/ijdb.150206am
Publikováno v:
Developmental Biology. 425(2)
We recently demonstrated a critical role for two-pore channel type 2 (TPC2)-mediated Ca(2+) release during the differentiation of slow (skeletal) muscle cells (SMC) in intact zebrafish embryos, via the introduction of a translational-blocking morphol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53d7baae4d10403b1096188c4aa8cb7d
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
Cold Spring Harb Perspect Biol
Since the identification of nicotinic acid adenine dinucleotide phosphate (NAADP) and its putative target, the two-pore channel (TPC), the NAADP/TPC/Ca(2+) signaling pathway has been reported to play a role in a diverse range of functions in a variet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41fb72a561064c92fde2e680938e7dcd
https://doi.org/10.1101/cshperspect.a035170
https://doi.org/10.1101/cshperspect.a035170