Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jeffrey J. Bajramovic̀"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
TLR-induced signaling initiates inflammatory responses in cells of the innate immune system. These responses are amongst others characterized by the secretion of high levels of pro-inflammatory cytokines, which are tightly regulated and adapted to th
Externí odkaz:
https://doaj.org/article/76a5cd7d512a4d26bf9f10712ddcf5f5
Autor:
Ella A. Zuiderwijk-Sick, Céline van der Putten, Raissa Timmerman, Jennifer Veth, Erica M. Pasini, Linda van Straalen, Paul van der Valk, Sandra Amor, Jeffrey J. Bajramovic
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interleukin (IL)-4 is a cytokine that affects both adaptive and innate immune responses. In the central nervous system, microglia express IL-4 receptors and it has been described that IL-4-exposed microglia acquire anti-inflammatory properties. We he
Externí odkaz:
https://doaj.org/article/000ca16e7f24436986f08d1b1ba48e40
Autor:
Coraline Chéneau, Karsten Eichholz, Tuan Hiep Tran, Thi Thu Phuong Tran, Océane Paris, Corinne Henriquet, Jeffrey J. Bajramovic, Martine Pugniere, Eric J. Kremer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite decades of clinical and preclinical investigations, we still poorly grasp our innate immune response to human adenoviruses (HAdVs) and their vectors. In this study, we explored the impact of lactoferrin on three HAdV types that are being used
Externí odkaz:
https://doaj.org/article/50e6d73b09c64f14b5454b2443e9f144
Autor:
Arend H. Sikkema, Josephine M. J. Stoffels, Peng Wang, Frederike J. Basedow, Robbert Bulsink, Jeffrey J. Bajramovic, Wia Baron
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-17 (2018)
Abstract Background Means to promote endogenous remyelination in multiple sclerosis (MS) benefit from insights into the role of inhibitory molecules that preclude remyelination. Fibronectin assembles into aggregates in MS, which impair oligodendrocyt
Externí odkaz:
https://doaj.org/article/b5ac1e2b50d540f0b9784401534f4c25
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Neuroinflammation is a common feature in neurodegenerative diseases and strategies to modulate neuroinflammatory processes are increasingly considered as therapeutic options. In such strategies, glia cells rather than neurons represent the cellular t
Externí odkaz:
https://doaj.org/article/8d5f595cbdc04c3aad305cbb6e972ed4
Autor:
Ché Serguera, Jennifer Veth, Roger Le Grand, Julie Massonneau, Hugues Contamin, Joachim Confais, Emilie Avazeri, Claire-Maëlle Fovet, Lev Stimmer, Anke 't Jong, Philippe Horellou, Kumaran Deiva, Bert A. 't Hart, Audrey Perrin, Guylaine Miotello, Jeffrey J. Bajramovic, Jean Armengaud
Publikováno v:
Laboratory Investigation, 101(11), 1513-1522. SPRINGERNATURE
The authors describe quantitatively and qualitatively different forms of experimental autoimmune encephalitis (EAE) in cynomolgus macaques. They found that bacterial contaminants within recombinant human myelin oligodendrocyte glycoprotein seemed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9598a51dda540559a83f3077f9deb5a7
https://doi.org/10.1038/s41374-021-00646-x
https://doi.org/10.1038/s41374-021-00646-x
Autor:
Raissa Timmerman, Ella A. Zuiderwijk‐Sick, Nynke Oosterhof, Anke E. J. 't Jong, Jennifer Veth, Saskia M. Burm, Tjakko J. van Ham, Jeffrey J. Bajramovic
Publikováno v:
Glia, 70(4), 728-747. Wiley
GLIA, 70(4), 728-747. John Wiley & Sons Inc.
GLIA, 70(4), 728-747. John Wiley & Sons Inc.
Microglia are increasingly being recognized as druggable targets in neurodegenerative disorders, and good in vitro models are crucial to address cell biological questions. Major challenges are to recapitulate the complex microglial morphology and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8c9ebb6fc2c7a0034b330fbd03e7db
https://pubmed.ncbi.nlm.nih.gov/34961968
https://pubmed.ncbi.nlm.nih.gov/34961968
Autor:
Joannes A. A. Reijers, Richard Verbeek, Jacobus Burggraaf, Matthijs Moerland, Jeffrey J. Bajramovic, Karen E. Malone
Publikováno v:
British Journal of Clinical Pharmacology
Drug safety is an important issue, especially in the experimental phases of development. Adverse immunostimulation (AI) is sometimes encountered following treatment with biopharmaceuticals, which can be life-threatening if it results in a severe syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0604a99fc1e34c1811472b3f84304292
https://doi.org/10.1111/bcp.13938
https://doi.org/10.1111/bcp.13938
Autor:
Lev, Stimmer, Joachim, Confais, Anke't, Jong, Jennifer, Veth, Claire-Maëlle, Fovet, Philippe, Horellou, Julie, Massonneau, Audrey, Perrin, Guylaine, Miotello, Emilie, Avazeri, Bert't, Hart, Kumaran, Deiva, Roger, Le Grand, Jean, Armengaud, Jeffrey J, Bajramovic, Hugues, Contamin, Ché, Serguera
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 101(11)
Experimental autoimmune encephalitis (EAE) is a well-recognized model for the study of human acquired demyelinating diseases (ADD), a group of inflammatory disorders of the central nervous system (CNS) characterized by inflammation, myelin loss, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f366af0ff7d95153331e55156312664b
https://pubmed.ncbi.nlm.nih.gov/34376778
https://pubmed.ncbi.nlm.nih.gov/34376778
Publikováno v:
ALTEX. 39(1)
The in vivo histamine sensitization test (HIST) has historically been performed to guarantee the safety of acellular pertussis vaccine batches. Non-compliance of batches is primarily associated with the presence of low levels of pertussis toxin (PT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f398bc9e51bb6b0d47930d1f1e7e185b
https://pubmed.ncbi.nlm.nih.gov/34654933
https://pubmed.ncbi.nlm.nih.gov/34654933