Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jeffrey J Lovelace"'
Autor:
Mona Al-Mugotir, Jeffrey J Lovelace, Joseph George, Mika Bessho, Dhananjaya Pal, Lucas Struble, Carol Kolar, Sandeep Rana, Amarnath Natarajan, Tadayoshi Bessho, Gloria E O Borgstahl
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248941 (2021)
Synthetic lethality is a successful strategy employed to develop selective chemotherapeutics against cancer cells. Inactivation of RAD52 is synthetically lethal to homologous recombination (HR) deficient cancer cell lines. Replication protein A (RPA)
Externí odkaz:
https://doaj.org/article/61c7e66c5d784f338511623f59b276e2
Autor:
William E. Lutz, Jahaun Azadmanesh, Jeffrey J. Lovelace, Carol Kolar, Leighton Coates, Kevin L. Weiss, Gloria E. O. Borgstahl
Publikováno v:
npj Microgravity, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract The NASA mission Perfect Crystals used the microgravity environment on the International Space Station (ISS) to grow crystals of human manganese superoxide dismutase (MnSOD)—an oxidoreductase critical for mitochondrial vitality and human h
Externí odkaz:
https://doaj.org/article/49dbfaf2f2a048809dafc8c9d0140fcc
Autor:
Jahaun Azadmanesh, Mohamed A. Seleem, Lucas Struble, Nicholas A. Wood, Derek J. Fisher, Jeffrey J. Lovelace, Antonio Artigues, Aron W. Fenton, Gloria E.O. Borgstahl, Scot P. Ouellette, Martin Conda-Sheridan
Publikováno v:
The Journal of biological chemistry. 299(1)
Chlamydia trachomatis (ct) is the most reported bacterial sexually transmitted infection worldwide and the leading cause of preventable blindness. Caseinolytic proteases (ClpP) from pathogenic bacteria are attractive antibiotic targets, particularly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46808406335ee5e0a19307dfbdcd5cf
https://pubmed.ncbi.nlm.nih.gov/36463962
https://pubmed.ncbi.nlm.nih.gov/36463962
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
Two modulated structures of the Hyp-1–ANS complex with different unit-cell dimensions and contents were analyzed in (3+1)D superspace, revealing that they are very similar if not the same higher-dimensional structure with a slight shift in the q ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a74ba334fa38e4a0d036a45ea9a2db
https://doi.org/10.1107/s2059798321003740
https://doi.org/10.1107/s2059798321003740
Publikováno v:
Crystallogr Rev
Macromolecular crystal structure determination can be complicated or brought to a halt by crystal imperfections. These issues motivated us to write up what we affectionately call ‘The Definitive Hi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd13a289e1902d52216de7169d57116f
https://doi.org/10.1080/0889311x.2019.1692341
https://doi.org/10.1080/0889311x.2019.1692341
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
A higher dimensional superspace description accounts for an unexpected supercell refinement result.
Theoretically, crystals with supercells exist at a unique crossroads where they can be considered as either a large unit cell with closely spaced
Theoretically, crystals with supercells exist at a unique crossroads where they can be considered as either a large unit cell with closely spaced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0596628a1738e8718a5fe5d7de3b98b
https://doi.org/10.1107/s2059798319011082
https://doi.org/10.1107/s2059798319011082
Autor:
Dhananjaya Pal, Mika Bessho, Joseph W. George, Gloria E. O. Borgstahl, Tadayoshi Bessho, Lucas R. Struble, Sandeep Rana, Jeffrey J. Lovelace, Mona Al-Mugotir, Carol Kolar, Amarnath Natarajan
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248941 (2021)
PLoS ONE
PLoS ONE
Synthetic lethality is a successful strategy employed to develop selective chemotherapeutics against cancer cells. Inactivation of RAD52 is synthetically lethal to homologous recombination (HR) deficient cancer cell lines. Replication protein A (RPA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c624fd19c4fc13767612c84f47b8a4
https://doaj.org/article/61c7e66c5d784f338511623f59b276e2
https://doaj.org/article/61c7e66c5d784f338511623f59b276e2
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:a104-a104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12a71a611ac05bc6ea418148df5f4cd0
https://doi.org/10.1107/s0108767321098950
https://doi.org/10.1107/s0108767321098950
Autor:
Paul L. Sorgen, Nicholas P. Schafer, Hamid Band, Jeffrey J. Lovelace, Gaelle Spagnol, Vimla Band, Gloria E. O. Borgstahl, Peter D. Simone, Riyaz A. Mir, Admir Kellezi, Carol Kolar
Publikováno v:
AIMS Biophysics, Vol 3, Iss 1, Pp 195-210 (2016)
AIMS biophysics
AIMS biophysics
The human homolog of Drosophila ecdysoneless protein (ECD) is a p53 binding protein that stabilizes and enhances p53 functions. Homozygous deletion of mouse Ecd is early embryonic lethal and Ecd deletion delays G1-S cell cycle progression. Importantl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78c6e7a36983c8b7e0fb5fe6c9430cf
https://doi.org/10.3934/biophy.2016.1.195
https://doi.org/10.3934/biophy.2016.1.195
Publikováno v:
Aperiodic 2018 ("9th Conference on Aperiodic Crystals").
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edca9da0bce924158a5b94003a6a6444
https://doi.org/10.31274/aperiodic2018-180810-18
https://doi.org/10.31274/aperiodic2018-180810-18