Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jeffrey J Beck"'
Autor:
Casey T Finnicum, Conor V Dolan, Gonneke Willemsen, Zachary M Weber, Jason L Petersen, Jeffrey J Beck, Veryan Codd, Dorret I Boomsma, Gareth E Davies, Erik A Ehli
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170765 (2017)
Telomere length has garnered interest due to the potential role it may play as a biomarker for the cellular aging process. Telomere measurements obtained from blood-derived DNA are often used in epidemiological studies. However, the invasive nature o
Externí odkaz:
https://doaj.org/article/9c6b79aed843451d94e7b5a62a088f8c
Autor:
Jeffrey J. Beck, John L. Slunecka, Brandon N. Johnson, Austin J. Van Asselt, Casey T. Finnicum, Cheryl Ageton, Amy Krie, Heidi Nickles, Kenneth Cowan, Jessica Maxwell, Dorret I. Boomsma, Eco de Geus, Erik A. Ehli, Jouke-Jan Hottenga
Publikováno v:
Cancers, Vol 16, Iss 8, p 1578 (2024)
Breast cancer (BC) is a complex disease affecting one in eight women in the USA. Advances in population genomics have led to the development of polygenic risk scores (PRSs) with the potential to augment current risk models, but replication is often l
Externí odkaz:
https://doaj.org/article/1271328c74754083903b5fe092a1de0f
Autor:
Austin J. Van Asselt, Jeffrey J. Beck, Casey T. Finnicum, Brandon N. Johnson, Noah Kallsen, Jouke Jan Hottenga, Eco J. C. de Geus, BIOS Consortium, Dorret I. Boomsma, Erik A. Ehli, Jenny van Dongen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14640 (2023)
The field of DNA methylation research is rapidly evolving, focusing on disease and phenotype changes over time using methylation measurements from diverse tissue sources and multiple array platforms. Consequently, identifying the extent of longitudin
Externí odkaz:
https://doaj.org/article/73acb6feb2fc4fa68d011bee50c95ed5
Autor:
Jeffrey J. Beck, Talitha Ahmed, Casey T. Finnicum, Koos Zwinderman, Erik A. Ehli, Dorret I. Boomsma, Jouke Jan Hottenga
Publikováno v:
Genes, Vol 14, Iss 7, p 1497 (2023)
Accurate inference of genetic ancestry is crucial for population-based association studies, accounting for population heterogeneity and structure. This study analyzes genome-wide SNP data from the Netherlands Twin Register to compare genetic ancestry
Externí odkaz:
https://doaj.org/article/b2e20dd5791a4ffba61c9bfffc812fff
Autor:
Veronika V. Odintsova, Valerie Rebattu, Fiona A. Hagenbeek, René Pool, Jeffrey J. Beck, Erik A. Ehli, Catharina E. M. van Beijsterveldt, Lannie Ligthart, Gonneke Willemsen, Eco J. C. de Geus, Jouke-Jan Hottenga, Dorret I. Boomsma, Jenny van Dongen
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
We examined the performance of methylation scores (MS) and polygenic scores (PGS) for birth weight, BMI, prenatal maternal smoking exposure, and smoking status to assess the extent to which MS could predict these traits and exposures over and above t
Externí odkaz:
https://doaj.org/article/78fc2e9782944a2ba13650d77ee9f397
Autor:
Veronika V, Odintsova, Matthew, Suderman, Fiona A, Hagenbeek, Doretta, Caramaschi, Jouke-Jan, Hottenga, René, Pool, Conor V, Dolan, Lannie, Ligthart, Catharina E M, van Beijsterveldt, Gonneke, Willemsen, Eco J C, de Geus, Jeffrey J, Beck, Erik A, Ehli, Gabriel, Cuellar-Partida, David M, Evans, Sarah E, Medland, Caroline L, Relton, Dorret I, Boomsma, Bastiaan T, Heijmans
Publikováno v:
Odintsova, V V, Hagenbeek, F A, Hottenga, J J, Pool, R, Dolan, C V, Ligthart, L, van Beijsterveldt, C E M, Willemsen, G, de Geus, E J C, Beck, J J, Ehli, E A, Boomsma, D I, van Dongen, J & BIOS Consortium 2022, ' DNA methylation in peripheral tissues and left-handedness ', Scientific Reports, vol. 12, no. 1, 5606, pp. 1-16 . https://doi.org/10.1038/s41598-022-08998-0
Scientific Reports, 12(1):5606, 1-16. Nature Publishing Group
Scientific Reports, 12(1):5606, 1-16. Nature Publishing Group
Handedness has low heritability and epigenetic mechanisms have been proposed as an etiological mechanism. To examine this hypothesis, we performed an epigenome-wide association study of left-handedness. In a meta-analysis of 3914 adults of whole-bloo
Autor:
Tammy Jung, Erik A. Ehli, J. Kittelsrud, Noah A. Kallsen, Patricia E. Huizenga, Vikki Petersen, Brittany Holm, Jeffrey J. Beck, Gareth E. Davies
Publikováno v:
Kittelsrud, J M, Ehli, E A, Petersen, V, Jung, T, Beck, J J, Kallsen, N, Huizenga, P, Holm, B & Davies, G E 2019, ' Avera Twin Register Growing Through Online Consenting and Survey Collection ', Twin Research and Human Genetics, vol. 22, no. 6, pp. 686-690 . https://doi.org/10.1017/thg.2019.73
Twin Research and Human Genetics, 22(6), 686-690. Australian Academic Press
Twin Research and Human Genetics, 22(6), 686-690. Australian Academic Press
The aim of the Avera Twin Register (ATR) is to establish a prospective longitudinal repository of twins, multiples, siblings and family members’ biological samples to study environmental and genetic influences on health and disease. Also, it is our
Autor:
Christel M. Davis, Erik A. Ehli, Dorret I. Boomsma, Gareth E. Davies, Casey T. Finnicum, Jeffrey J. Beck, Gonneke Willemsen, Conor V. Dolan, Eco J. C. de Geus
Publikováno v:
BMC Microbiology, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Microbiology
Finnicum, C T, Beck, J J, Dolan, C V, Davis, C, Willemsen, G, Ehli, E A, Boomsma, D I, Davies, G E & de Geus, E J C 2019, ' Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk ', BMC Microbiology, vol. 19, no. 1, 230, pp. 1-10 . https://doi.org/10.1186/s12866-019-1602-8
BMC Microbiology, 19(1):230, 1-10. BioMed Central
BMC Microbiology
Finnicum, C T, Beck, J J, Dolan, C V, Davis, C, Willemsen, G, Ehli, E A, Boomsma, D I, Davies, G E & de Geus, E J C 2019, ' Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk ', BMC Microbiology, vol. 19, no. 1, 230, pp. 1-10 . https://doi.org/10.1186/s12866-019-1602-8
BMC Microbiology, 19(1):230, 1-10. BioMed Central
Background The gut microbiota composition is known to be influenced by a myriad of factors including the host genetic profile and a number of environmental influences. Here, we focus on the environmental influence of cohabitation on the gut microbiot
Autor:
Erik A. Ehli, Jeffrey J. Beck, John L. Slunecka, René Pool, Jouke-Jan Hottenga, Matthijs D. van der Zee, Casey T. Finnicum, Brandon N. Johnson, Eco J. C. de Geus
Publikováno v:
Slunecka, J L, van der Zee, M D, Beck, J J, Johnson, B N, Finnicum, C T, Pool, R, Hottenga, J J, de Geus, E J C & Ehli, E A 2021, ' Implementation and implications for polygenic risk scores in healthcare ', Human Genomics, vol. 15, 46, pp. 1-18 . https://doi.org/10.1186/s40246-021-00339-y
Human Genomics, Vol 15, Iss 1, Pp 1-18 (2021)
Human Genomics
Human Genomics, Vol 15, Iss 1, Pp 1-18 (2021)
Human Genomics
Increasing amounts of genetic data have led to the development of polygenic risk scores (PRSs) for a variety of diseases. These scores, built from the summary statistics of genome-wide association studies (GWASs), are able to stratify individuals bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::091abbc0e6fca5386b3d41f3b97fda3a
https://hdl.handle.net/1871.1/754cd848-fd37-40fe-a6df-b6ebaa05156c
https://hdl.handle.net/1871.1/754cd848-fd37-40fe-a6df-b6ebaa05156c
Autor:
Anu Loukola, Jeffrey J. Beck, J. Kittelsrud, Conor V. Dolan, Nicholas G. Martin, Kauko Heikkilä, Jouke-Jan Hottenga, Teemu Palviainen, Hamdi Mbarek, Kaare Christensen, Michel G. Nivard, Miina Ollikainen, Gonneke Willemsen, Robert Plomin, Scott D. Gordon, Lu Yi, Matthijs D. van der Zee, Toos C. E. M. van Beijsterveldt, Bart M. L. Baselmans, Sebastian Lundström, Marianne Nygaard, Lene Christiansen, Eva Krapohl, Catarina Almqvist, Meike Bartels, Xu Chen, Patrik K. E. Magnusson, Casey T. Finnicum, Dorret I. Boomsma, Eco J. C. de Geus, Birgit Debrabant, Margot P van de Weijer, Erik A. Ehli, René Pool
Publikováno v:
Beck, J J, Pool, R, van de Weijer, M, Chen, X, Krapohl, E, Gordon, S D, Nygaard, M, Debrabant, B, Palviainen, T, van der Zee, M D, Baselmans, B, Finnicum, C T, Yi, L, Lundström, S, van Beijsterveldt, T, Christiansen, L, Heikkilä, K, Kittelsrud, J, Loukola, A, Ollikainen, M, Christensen, K, Martin, N G, Plomin, R, Nivard, M, Bartels, M, Dolan, C, Willemsen, G, de Geus, E, Almqvist, C, Magnusson, P K E, Mbarek, H, Ehli, E A, Boomsma, D I & Hottenga, J-J 2021, ' Genetic Meta-Analysis of Twin Birth Weight Shows High Genetic Correlation with Singleton Birth Weight ', Human Molecular Genetics, vol. 30, no. 19, pp. 1894-1905 . https://doi.org/10.1093/hmg/ddab121
Human Molecular Genetics
Beck, J J, Pool, R, Van De Weijer, M, Chen, X, Krapohl, E, Gordon, S D, Nygaard, M, Debrabant, B, Palviainen, T, Van Der Zee, M D, Baselmans, B, Finnicum, C T, Yi, L, Lundström, S, Van Beijsterveldt, T, Christiansen, L, Heikkilä, K, Kittelsrud, J, Loukola, A, Ollikainen, M, Christensen, K, Martin, N G, Plomin, R, Nivard, M, Bartels, M, Dolan, C, Willemsen, G, De Geus, E, Almqvist, C, Magnusson, P K E, Mbarek, H, Ehli, E A, Boomsma, D I & Hottenga, J J 2021, ' Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight ', Human molecular genetics, vol. 30, no. 19, pp. 1894-1905 . https://doi.org/10.1093/hmg/ddab121
Human molecular genetics, 30(19), 1894-1905. Oxford University Press
Human Molecular Genetics
Beck, J J, Pool, R, Van De Weijer, M, Chen, X, Krapohl, E, Gordon, S D, Nygaard, M, Debrabant, B, Palviainen, T, Van Der Zee, M D, Baselmans, B, Finnicum, C T, Yi, L, Lundström, S, Van Beijsterveldt, T, Christiansen, L, Heikkilä, K, Kittelsrud, J, Loukola, A, Ollikainen, M, Christensen, K, Martin, N G, Plomin, R, Nivard, M, Bartels, M, Dolan, C, Willemsen, G, De Geus, E, Almqvist, C, Magnusson, P K E, Mbarek, H, Ehli, E A, Boomsma, D I & Hottenga, J J 2021, ' Genetic meta-analysis of twin birth weight shows high genetic correlation with singleton birth weight ', Human molecular genetics, vol. 30, no. 19, pp. 1894-1905 . https://doi.org/10.1093/hmg/ddab121
Human molecular genetics, 30(19), 1894-1905. Oxford University Press
Birth weight (BW) is an important predictor of newborn survival and health and has associations with many adult health outcomes, including cardio-metabolic disorders, autoimmune diseases, and mental health. On average, twins have a lower BW than sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68816df5d57c253bdd993e160457e57c
https://findresearcher.sdu.dk:8443/ws/files/191806422/ddab121.pdf
https://findresearcher.sdu.dk:8443/ws/files/191806422/ddab121.pdf