Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jeffrey Houlton"'
Autor:
Kenneth R. Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B. Deutsch, Thomas J. Ow, Robert G. Maki, John Pang, Cherie-Ann O. Nathan, Daniel Clayburgh, Jason G. Newman, Elyse Brinkmann, Michael J. Wagner, Seth M. Pollack, Matthew J. Thompson, Ryan J. Li, Vikas Mehta, Bradley A. Schiff, Barry I. Wenig, Paul L. Swiecicki, Alice L. Tang, Jessica L. Davis, Annemieke van Zante, Jessica A. Bertout, Wendy Jenkins, Atticus Turner, Marc Grenley, Connor Burns, Jason P. Frazier, Angela Merrell, Kimberly H. W. Sottero, Jonathan M. J. Derry, Kate C. Gillespie, Bre Mills, Richard A. Klinghoffer
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Drug development is systemically inefficient. Research and development costs for novel therapeutics average hundreds of millions to billions of dollars, with the overall likelihood of approval estimated to be as low as 6.7% for oncology
Externí odkaz:
https://doaj.org/article/df356ddd88154387999a5c867f337370
Autor:
Michael Wagner, Kenneth Gundle, Wendy Jenkins, Cherie-Ann Nathan, Karthik Rajasekaran, Jeffrey Houlton, Daniel Clayburgh, Elyse Brinkmann, John Pang, Annemieke Van Zante, Jessica Davis, Connor Burns, Jason Frazier, Emily Beirne, Angela Merrell, Bre Mills, Jonathan Derry, Hanrong Sang, Atticus Turner, Marc Grenley, Nathan Schauer, Richard Klinghoffer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2626a56932aa4490b7e1fa8b5af9b7d9
Autor:
Jeffrey Houlton, Daniel Clayburgh, Ryan Li, Nathan Schauer, Marc Grenley, Connor Burns, Angela Merrell, Jason Frazier, Jonathan Derry, Emily Beirne, Wendy Jenkins, Allison Berger, Richard Klinghoffer
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Jorge Luis Galeano Niño, Hanrui Wu, Kaitlyn D. LaCourse, Andrew G. Kempchinsky, Alexander Baryiames, Brittany Barber, Neal Futran, Jeffrey Houlton, Cassie Sather, Ewa Sicinska, Alison Taylor, Samuel S. Minot, Christopher D. Johnston, Susan Bullman
Publikováno v:
Nature. 611(7937)
The tumour-associated microbiota is an intrinsic component of the tumour microenvironment across human cancer types1,2. Intratumoral host–microbiota studies have so far largely relied on bulk tissue analysis1–3, which obscures the spatial distrib
Autor:
Natalie F. Uy, Kevin Ng, Jenna M. Voutsinas, Vicky Wu, Neal D. Futran, Jeffrey Houlton, Brittany Barber, George E. Laramore, Upendra Parvathaneni, Jay Justin Liao, Cristina P. Rodriguez
Publikováno v:
Journal of Clinical Oncology. 40:296-296
296 Background: Immune checkpoint inhibitors (ICI) are approved for recurrent and/or metastatic squamous head and neck cancers (R/M HNSCC). Landmark trials have shown stable or improved patient (pt) reported quality of life outcomes. It is unclear ho
Autor:
Jeffrey Houlton, Harrison Cash, Haodong Xu, Paul L. Swiecicki, Keith Casper, Steven B. Chinn, Daniel R. Clayburgh, Ryan J. Li, Robert J. Christian, Aaron Halfpenny, Annemieke van Zante, Beryl A. Hatton, Kimberly Sottero, Marc O. Grenley, Connor Burns, Jason Frazier, Jonathan Derry, Gloria Kung, Emily Beirne, Nathan J. Schauer, Atticus Turner, Wendy Jenkins, Kirsten Anderson, Richard A. Klinghoffer, Dennis Huszar, Allison Berger, Karuppiah Kannan
Publikováno v:
Cancer Research. 82:CT139-CT139
Purpose/Objectives: The human tumor microenvironment (TME) has a dramatic impact on cancer prognosis and therapeutic response, but accurate models of the native TME do not exist. The Comparative In Vivo Oncology (CIVO) platform was developed as a mea