Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jeffrey Gersch"'
Autor:
Ka-Cheung Luk, Jeffrey Gersch, Barbara J. Harris, Vera Holzmayer, Dora Mbanya, Silvia Sauleda, Mary A. Rodgers, Gavin Cloherty
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract HBV produces unspliced and spliced RNAs during replication. Encapsidated spliced RNA is converted into DNA generating defective virions that are detected in plasma and associated with HCC development. Herein we describe a quantitative real-t
Externí odkaz:
https://doaj.org/article/b698668b33264645924fce0e1da59735
Autor:
Kelly E. Coller, Veronica Bruce, Michael Cassidy, Jeffrey Gersch, Matthew B. Frankel, Ana Vallari, Gavin Cloherty, John Hackett, Jennifer L. Evans, Kimberly Page, George J. Dawson
Publikováno v:
Emerging Infectious Diseases, Vol 26, Iss 2, Pp 265-272 (2020)
Most human pegivirus 2 (HPgV-2) infections are associated with past or current hepatitis C virus (HCV) infection. HPgV-2 is thought to be a bloodborne virus: higher prevalence of active infection has been found in populations with a history of parent
Externí odkaz:
https://doaj.org/article/7ee0e28cb7324ddb8c66f4fe44298b71
Development and performance of prototype serologic and molecular tests for hepatitis delta infection
Autor:
Kelly E. Coller, Emily K. Butler, Ka-Cheung Luk, Mary A. Rodgers, Michael Cassidy, Jeffrey Gersch, Anne L. McNamara, Mary C. Kuhns, George J. Dawson, Lazare Kaptue, Birgit Bremer, Heiner Wedemeyer, Gavin A. Cloherty
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Worldwide, an estimated 5% of hepatitis B virus (HBV) infected people are coinfected with hepatitis delta virus (HDV). HDV infection leads to increased mortality over HBV mono-infection, yet HDV diagnostics are not widely available. Prototyp
Externí odkaz:
https://doaj.org/article/cecdf5f3f90443218de37d948b89f5d9
Autor:
Romina Salpini, Vincenzo Malagnino, Lorenzo Piermatteo, Tiziana Mulas, Mohammad Alkhatib, Rossana Scutari, Elisabetta Teti, Carlotta Cerva, Katia Yu La Rosa, Marta Brugneti, Ada Bertoli, Benedetta Rossi, Vera Holzmayer, Jeffrey Gersch, Mary Kuhns, Gavin Cloherty, Francesca Ceccherini-Silberstein, Carlo-Federico Perno, Marco Iannetta, Massimo Andreoni, Loredana Sarmati, Valentina Svicher
Publikováno v:
Microorganisms, Vol 8, Iss 11, p 1819 (2020)
The anti-HBc-positive/HBsAg-negative status is frequent in HIV-infection and correlates with poor survival. Here, by highly-sensitive assays, we evaluate cryptic HBV replication and factors correlated with its detection in 81 anti-HBc-positive/HBsAg-
Externí odkaz:
https://doaj.org/article/ebeef6c8bda6439b89f6cd9417bf0ef7
Autor:
Mary A. Rodgers, Pir A. Shah, Mark Anderson, Ana S. Vallari, Jeffrey Gersch, Dora Mbanya, Silvia Sauleda Oliveras, Saad Choudhry, Thomas P. Leary, Mary C. Kuhns, George J. Dawson, Gavin A. Cloherty, Daryl T.Y. Lau
Publikováno v:
Hepatology Communications. 7
Autor:
Gavin Cloherty, James Fung, Lung-Yi Mak, Wai-Kay Seto, Jeffrey Gersch, Man-Fung Yuen, Danny Ka-Ho Wong
Publikováno v:
Hepatology. 73:2167-2179
Large-scale comprehensive studies on HBV RNA in chronic hepatitis B are lacking. We aimed to study the HBV RNA profile and its correlation with other viral markers in patients with chronic hepatitis B who are treatment-naïve and patients receiving n
Autor:
Ning Chow, Ka Shing Cheung, Kwan-Lung Ko, Danny Ka-Ho Wong, Wai-Pan To, Wai-Kay Seto, Kevin Sh Liu, Man-Fung Yuen, Yuk-Fai Lam, Gavin Cloherty, Jeffrey Gersch, James Fung, Lung-Yi Mak
Publikováno v:
Gut. 70:775-783
BackgroundTreatment cessation in chronic HBV infection may be durable in certain patient subgroups before hepatitis B surface antigen (HBsAg) seroclearance. The role of serum HBV RNA in determining treatment cessation suitability has not been well-in
Autor:
Christiana Moigboi, Gavin Cloherty, Ivana Carey, Bo Wang, Geoffrey Dusheiko, Jeffrey Gersch, Kosh Agarwal, Mary C. Kuhns
Publikováno v:
Hepatology
Background and aims A dichotomous separation of hepatitis B viral DNA and hepatitis B surface antigen (HBsAg) concentrations occurs during the natural history and treatment of chronic hepatitis B. We have evaluated the ability of hepatitis B virus (H
Autor:
Tiziana Mulas, Vera Holzmayer, Vincenzo Malagnino, Carlo Federico Perno, Gavin Cloherty, Carlotta Cerva, Mary C. Kuhns, Francesca Ceccherini-Silberstein, Rossana Scutari, Loredana Sarmati, Jeffrey Gersch, Benedetta Rossi, Elisabetta Teti, Mohammad Alkhatib, Marta Brugneti, Katia Yu La Rosa, Valentina Svicher, Romina Salpini, Marco Iannetta, Massimo Andreoni, L. Piermatteo, Ada Bertoli
Publikováno v:
Microorganisms
Microorganisms, Vol 8, Iss 1819, p 1819 (2020)
Volume 8
Issue 11
Microorganisms, Vol 8, Iss 1819, p 1819 (2020)
Volume 8
Issue 11
The anti-HBc-positive/HBsAg-negative status is frequent in HIV-infection and correlates with poor survival. Here, by highly-sensitive assays, we evaluate cryptic HBV replication and factors correlated with its detection in 81 anti-HBc-positive/HBsAg-
Autor:
Kosh Agarwal, Gavin Cloherthy, Jeffrey Gersch, Geoffrey Dusheiko, Ivana Carey, Bo Wang, Christiana Moigboi
Publikováno v:
Abstracts.
Post-partum ALT increases are observed in 30% of HBsAg+ mothers and are also noticed in mothers administered nucleoside analogues (NA) to prevent mother-to-child transmission (MTCT). As such flares may be injurious we have studied the utility of nove