Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jeffrey G. Shannon"'
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Yersinia pestis is a gram-negative, zoonotic, bacterial pathogen, and the causative agent of plague. The bubonic form of plague occurs subsequent to deposition of bacteria in the skin by the bite of an infected flea. Neutrophils are recruited to the
Externí odkaz:
https://doaj.org/article/51584516a5be4b309e5878e2de3c9a10
Autor:
Jeffrey G. Shannon, Aaron M. Hasenkrug, David W. Dorward, Vinod Nair, Aaron B. Carmody, B. Joseph Hinnebusch
Publikováno v:
mBio, Vol 4, Iss 5 (2013)
ABSTRACT The majority of human Yersinia pestis infections result from introduction of bacteria into the skin by the bite of an infected flea. Once in the dermis, Y. pestis can evade the host’s innate immune response and subsequently disseminate to
Externí odkaz:
https://doaj.org/article/1f2e35ecf3274e0da4d586d39ce847e5
Autor:
Jeffrey G Shannon, B Joseph Hinnebusch
Publikováno v:
Journal of Leukocyte Biology.
Neutrophils represent a first line of defense against a wide variety of microbial pathogens. Transduction with an estrogen receptor–Hoxb8 transcription factor fusion construct conditionally immortalizes myeloid progenitor cells (NeutPro) capable of
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal models that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acc6cacad3e94dcb00d2fb0b4b8e651
https://doi.org/10.1101/2021.09.17.460664
https://doi.org/10.1101/2021.09.17.460664
Publikováno v:
Infect Immun
Bubonic plague results when Yersinia pestis is deposited in the skin via the bite of an infected flea. Bacteria then traffic to the draining lymph node (dLN) where they replicate to large numbers. Without treatment, this infection can result in highl
Intravital Confocal Microscopy of Dermal Innate Immune Responses to Flea-Transmitted Yersinia pestis
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2010
The technique known as intravital microscopy (IVM), when used in conjunction with transgenic mice expressing fluorescent proteins in various cell populations, is a powerful tool with the potential to provide new insights into host-pathogen interactio
Intravital Confocal Microscopy of Dermal Innate Immune Responses to Flea-Transmitted Yersinia pestis
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995400
The technique known as intravital microscopy (IVM), when used in conjunction with transgenic mice expressing fluorescent proteins in various cell populations, is a powerful tool with the potential to provide new insights into host-pathogen interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::348020fbe9bc0b626ddca91fb1b1b003
https://doi.org/10.1007/978-1-4939-9541-7_5
https://doi.org/10.1007/978-1-4939-9541-7_5
Autor:
Scott D. Kobayashi, Jeffrey G. Shannon, Aaron M. Hasenkrug, B. Joseph Hinnebusch, Justin L. Spinner
Publikováno v:
Microbes and Infection. 18:21-29
Polymorphonuclear leukocytes, in addition to their direct bactericidal activities, produce cytokines involved in the activation and regulation of the innate and adaptive immune response to infection. In this study we evaluated the cytokine response o
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Yersinia pestis is a gram-negative, zoonotic, bacterial pathogen, and the causative agent of plague. The bubonic form of plague occurs subsequent to deposition of bacteria in the skin by the bite of an infected flea. Neutrophils are recruited to the