Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey F.W. Keuren"'
Autor:
Kon-Siong G. Jie, Johannes A. Kragten, Mick E. P. W. Frissen, Math P. G. Leers, Mark Huts, Jeffrey F.W. Keuren
Publikováno v:
Thrombosis and Haemostasis. 110:101-109
SummaryThis study was performed to gain further insight in pro- and anticoagulant characteristics of leukocytes in acute coronary syndrome (ACS). For this purpose, patients presenting on the emergency department (ED) with anginal chest pain were incl
Publikováno v:
Transfusion. 47:1880-1888
BACKGROUND Microparticles (MPs) support coagulation and can be helpful in restoring the hemostatic system in thrombocytopenic patients. The anticoagulant properties of MPs shed during storage of platelets (PLTs) have not been studied yet. STUDY DESIG
Autor:
Hans Ulrichts, Hans Deckmyn, Simone J.H. Wielders, Tilman M. Hackeng, Theo Lindhout, Edouard M. Bevers, Johan W. M. Heemskerk, Jeffrey F.W. Keuren
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:1499-1505
Objective— In the blood coagulation process, the rate of thrombin formation is critically dependent on phosphatidylserine (PtdSer) at the surface of activated platelets. Thrombin synergistically enhances the collagen-induced platelet procoagulant r
Autor:
Jean-Pierre Girma, Peter J. Lenting, Jeffrey F.W. Keuren, Cécile V. Denis, Dominique Baruch, Paulette Legendre, Theo Lindhout
Publikováno v:
Blood. 103:1741-1746
Fibrin is actively involved in platelet reactions essential for thrombus growth, in which von Willebrand factor (VWF) might be an important mediator. The aim of this study was to localize VWF domains that bind to fibrin and to determine their relevan
Autor:
Anita Driessen, Theo Lindhout, Simone J.H. Wielders, Michel Verhoeven, Marc Hendriks, Jeffrey F.W. Keuren
Publikováno v:
Arteriosclerosis Thrombosis and Vascular Biology, 24(3), 613-617. LIPPINCOTT WILLIAMS & WILKINS
Objective— Blood compatibility of artificial surfaces depends on their immunogenic and thrombogenic properties. Collagen’s weak antigenicity makes it an attractive candidate for stent coatings or fabrication of vascular grafts. However, the throm
Autor:
E. C. M. van Pampus, H.C. Hemker, J. Lodder, Marion A.H. Feijge, Karly Hamulyák, Kristof Vanschoonbeek, Jeffrey F.W. Keuren, Johan W. M. Heemskerk
Publikováno v:
Thrombosis and Haemostasis, 88(6), 931-937. Georg Thieme Verlag
Thrombin-induced Hyperactivity of Platelets of Young Stroke Patients.Vanschoonbeek K, Feijge MA, Keuren JF, Coenraad Hemker H, Lodder JJ, Hamulyak K, Van Pampus EC, Heemskerk JW.Dept. of Biochemistry, CARIM, University of Maastricht, P.O. Box 616, 62
Publikováno v:
Thrombosis and Haemostasis. 87:742-747
SummaryThrombus formation at an artificial surface in contact with blood is a complex process that encompasses accretion of platelets from flowing blood and fibrin deposition. Platelet adhesion and fibrin formation are intimately intertwined reaction
Autor:
Johan W. M. Heemskerk, Sandra Cauwenberghs, Jeffrey F.W. Keuren, Wim L.A.M. de Kort, Judith Heeremans, Joyce Curvers
Publikováno v:
Transfusion. 46(2)
BACKGROUND: During storage under blood bank conditions, platelets (PLTs) are known to secrete ADP. PLT stimulation by ADP results in refractoriness to restimulation, making this response one of the most unstable PLT reactions. The goal of this study
Autor:
Jeffrey F.W. Keuren, Theo Lindhout, George M. Willems, Marco Morra, Patrick T. Cahalan, Linda Cahalan, Simone J.H. Wielders
Publikováno v:
Biomaterials. 24(11)
Heparinization of artificial surfaces has been proven to reduce the intrinsic thrombogenicity of such surfaces. The mechanism by which immobilized heparin reduces thrombogenicity is not completely understood. In the present study heparin-, alginic ac