Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jeffrey F. Goldsmith"'
Autor:
Ikuya Sakai, Jeffrey F. Goldsmith, Woelsung Yi, Stuart J. Frank, G Gilliland, Jing Jiang, Yanming Zhao, Andrew S. Kraft
Publikováno v:
Journal of Biological Chemistry. 270:14776-14785
Growth hormone (GH) treatment of cells promotes activation of JAK2, a GH receptor (GHR)-associated tyrosine kinase. We now explore JAK2 regions required for GHR-induced signaling. Wild-type (WT) JAK2 and JAK2 molecules with deletions of the amino ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4eba60bc6519158605ba63fd8625635
https://doi.org/10.1074/jbc.270.24.14776
https://doi.org/10.1074/jbc.270.24.14776
Publikováno v:
Biochemical and biophysical research communications. 310(3)
The T cell receptor zeta chain is required for efficient receptor expression and contributes to T cell receptor-mediated activation of ZAP-70 and PLC-gamma1 as well as other signaling functions. A splice variant of zeta has been described which conta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55225a6301fc2d8a02fd6d0f49af9afd
https://pubmed.ncbi.nlm.nih.gov/14550268
https://pubmed.ncbi.nlm.nih.gov/14550268
Publikováno v:
Biochemical and biophysical research communications. 298(4)
Two isoforms of the src-family tyrosine kinase p59fyn have been shown to arise through alternative splicing of exon 7 of the fyn gene. These isoforms have been designated fynT, expressed in hematopoietic cells, and fynB, expressed in the brain. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6db31f0713565d47fef3116938a178
https://pubmed.ncbi.nlm.nih.gov/12408980
https://pubmed.ncbi.nlm.nih.gov/12408980
Autor:
Xiaoyong Yang, Jimmy Alele, Hiralal G. Maheshwari, Roy A. Black, Jeffrey F. Goldsmith, Jing Jiang, Stuart J. Frank, Gerhard Baumann
Publikováno v:
Endocrinology. 139(4)
GH, an important growth-promoting and metabolic hormone, exerts its biological effects by interacting with cell surface GH receptors (GHRs). The GHR is a single membrane-spanning protein that binds GH via its extracellular domain. The high affinity G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5634f76ad9a5137193b7aa919f4f741
https://pubmed.ncbi.nlm.nih.gov/9528979
https://pubmed.ncbi.nlm.nih.gov/9528979
Publikováno v:
The American journal of physiology. 273(5)
In this study, we examined human growth hormone (hGH)-induced changes in nonionic detergent solubility characteristics of its receptor (hGHR). Exposure of IM-9 cells to hGH caused a time- and concentration-dependent loss of immunoblottable detergent-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cad80706350e220ceb09dbd84a23c45
https://pubmed.ncbi.nlm.nih.gov/9374679
https://pubmed.ncbi.nlm.nih.gov/9374679