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Autor:
Xiaolin Zhao, Carla V. Finkielstein, Jeffrey Ellena, Mary K. Brannon, Kristen Fread, Wen Xiong, Daniel G. S. Capelluto, John H. Bushweller, Shuyan Xiao, Geoffrey Armstrong
Publikováno v:
Biophysical Journal. 110(3)
Early endosomes represent the first sorting station for vesicular ubiquitylated cargo. Cargo transport is mediated by the endosomal sorting complex required for transport (ESCRT) machinery. Similar to the structural organization of ESCRT-0 proteins,