Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Jeffrey Ecsedy"'
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background In mammalian cells, Aurora serine/threonine kinases (Aurora A, B, and C) are expressed in a cell cycle-dependent fashion as key mitotic regulators required for the maintenance of chromosomal stability. Aurora-A (AURKA) has been pr
Externí odkaz:
https://doaj.org/article/1207ddcb41364241abe187204ed5ecc4
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/1cc81304efed4b659ecfdeb4f3a7e1de
Autor:
Huifeng Niu, Hyunjin Shin, Feng Gao, Jacob Zhang, Brittany Bahamon, Hadi Danaee, Bohuslav Melichar, Russell J. Schilder, Robert L. Coleman, Gerald Falchook, Antoine Adenis, Kian Behbakht, Angela DeMichele, Elizabeth Claire Dees, Kimberly Perez, Ursula Matulonis, Piotr Sawrycki, Dirk Huebner, Jeffrey Ecsedy
Publikováno v:
EBioMedicine, Vol 25, Iss C, Pp 50-57 (2017)
Background: Alisertib (MLN8237) is an investigational, oral, selective Aurora A kinase inhibitor. Aurora A contains two functional single nucleotide polymorphisms (SNPs; codon 31 [F/I] and codon 57 [V/I]) that lead to functional changes. This study i
Externí odkaz:
https://doaj.org/article/24f33928b1e74afda898de75f7832eaf
Autor:
Jeffrey Ecsedy, Xiaoyan M. Zhang, Mark Manfredi, Prabitha Natarajan, Sakeena Syed, Jeremy Tchaicha, Meghan Walsh, Silvia Coma, Jill Cavanaugh, Alfredo C. Castro, Karen McGovern
Supplementary Table from Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a11276840ac47ab69018568d15800d
https://doi.org/10.1158/1535-7163.22523289.v1
https://doi.org/10.1158/1535-7163.22523289.v1
Autor:
Wael El-Rifai, Abbes Belkhiri, Regine Schneider-Stock, Tilman T. Rau, Alexander Zaika, Jeffrey Ecsedy, Frank Revetta, M. Kay Washington, Mohammed Soutto, DunFa Peng, Vikas Sehdev
PDF file - 155K, Effects of MLN8237 and CDDP on cell cycle progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cec53e2d6e4ebe1952ab66a90657d4b
https://doi.org/10.1158/1535-7163.22498819
https://doi.org/10.1158/1535-7163.22498819
Autor:
Wael El-Rifai, Abbes Belkhiri, Regine Schneider-Stock, Tilman T. Rau, Alexander Zaika, Jeffrey Ecsedy, Frank Revetta, M. Kay Washington, Mohammed Soutto, DunFa Peng, Vikas Sehdev
PDF file - 1.8MB, Effects of MLN8238 and CDDP on proliferation and apoptosis in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188c734f9f305721c06f07be25f8c219
https://doi.org/10.1158/1535-7163.22498816
https://doi.org/10.1158/1535-7163.22498816
Autor:
Wael El-Rifai, Abbes Belkhiri, Regine Schneider-Stock, Tilman T. Rau, Alexander Zaika, Jeffrey Ecsedy, Frank Revetta, M. Kay Washington, Mohammed Soutto, DunFa Peng, Vikas Sehdev
Esophageal adenocarcinomas are poorly responsive to chemotherapeutics. This study aimed to determine the levels of Aurora kinase A (AURKA) and the therapeutic potential of MLN8237, an investigational AURKA inhibitor, alone and in combination with cis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e18e8df5bf2e75e7c20f5186748f9e
https://doi.org/10.1158/1535-7163.c.6535975
https://doi.org/10.1158/1535-7163.c.6535975
Autor:
Jeffrey Ecsedy, Xiaoyan M. Zhang, Mark Manfredi, Prabitha Natarajan, Sakeena Syed, Jeremy Tchaicha, Meghan Walsh, Silvia Coma, Jill Cavanaugh, Alfredo C. Castro, Karen McGovern
Supplementary Figure from Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050525c3bfe144ac014dd2f1d4357a1f
https://doi.org/10.1158/1535-7163.22523295.v1
https://doi.org/10.1158/1535-7163.22523295.v1
Autor:
Wael El-Rifai, Abbes Belkhiri, Regine Schneider-Stock, Tilman T. Rau, Alexander Zaika, Jeffrey Ecsedy, Frank Revetta, M. Kay Washington, Mohammed Soutto, DunFa Peng, Vikas Sehdev
PDF file - 45K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3493ed504067ce99bdd7122b7f38b78
https://doi.org/10.1158/1535-7163.22498813.v1
https://doi.org/10.1158/1535-7163.22498813.v1
Autor:
Wael El-Rifai, Abbes Belkhiri, Regine Schneider-Stock, Tilman T. Rau, Alexander Zaika, Jeffrey Ecsedy, Frank Revetta, M. Kay Washington, Mohammed Soutto, DunFa Peng, Vikas Sehdev
PDF file - 229K, Details of cell cycle analysis following MLN8237 and CDDPand CDDP.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d8a0c32dbdbe61f08c506af24d7520
https://doi.org/10.1158/1535-7163.22498810
https://doi.org/10.1158/1535-7163.22498810