Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jeffrey D. Yingling"'
Autor:
Jill Marie Sturdivant, Bryan Sherman, Casey Kopczynski, Cheng-Wen Lin, Carmen L. Laethem, Susan M. Royalty, Mitchell A. Delong, Geoffrey Richard Heintzelman, Lori Moore, Jeffrey D. Yingling
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(10)
Inhibition of Rho kinase (ROCK) to improve fluid outflow through the trabecular meshwork and lower intraocular pressure is a strategy for the development of new anti-glaucoma agents. Alpha-aryl-beta-amino isoquinoline analogs were identified as poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08de9ede90e4b56b70667ffdec304066
https://pubmed.ncbi.nlm.nih.gov/27072905
https://pubmed.ncbi.nlm.nih.gov/27072905
Autor:
Maneesha Altekar, Jeffrey D. Yingling, Paul Taylor, Carol Ann Homon, Mohammed A. Kashem, Steven W. Mason, Lori Patnaude, Richard M. Nelson
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 11:33-41
With the transition from manual to robotic HTS in the last several years, assay optimization has become a significant bottleneck. Recent advances in robotic liquid handling have made it feasible to reduce assay optimization timelines with the applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1ab3a0afa95be12219ea4333c4bea2
https://doi.org/10.1016/j.jala.2005.11.001
https://doi.org/10.1016/j.jala.2005.11.001
Publikováno v:
Journal of Neurochemistry. 63:1271-1276
Glucocorticoids modulate signal transduction mechanisms in a number of cell systems. As the adrenal medulla is exposed to relatively high levels of adrenal cortical glucocorticoids in vivo, particularly during periods of stress, the aim of the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635de4c497107324e74f5a68b37547b0
https://doi.org/10.1046/j.1471-4159.1994.63041271.x
https://doi.org/10.1046/j.1471-4159.1994.63041271.x
Publikováno v:
Neuroscience Letters. 166:157-160
The present study examined the effect of protein kinase C (PKC) on cyclic AMP metabolism in PC18 cells, a recently developed model of the adrenal medullary chromaffin cell. Activation of PKC with phorbol 12-myristate 13-acetate (PMA) significantly po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea4c0fc2028b5ae983e94a5566a1662
https://doi.org/10.1016/0304-3940(94)90474-x
https://doi.org/10.1016/0304-3940(94)90474-x
Autor:
C. E. Ott, R. M. Raisch, J. B. Charles, David C. Randall, Joyce M. Evans, Charles F. Knapp, Jeffrey D. Yingling, H. M. Aral, David R. Brown
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 261:R473-R477
Pharmacological blockade of the renin-angiotensin converting enzyme reportedly alters the heart rate (HR) power spectrum in conscious dogs, suggesting that these hormones contribute to the short-term regulation of arterial blood pressure. We tested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e51af01ac839aa49230429860fa895
https://doi.org/10.1152/ajpregu.1991.261.2.r473
https://doi.org/10.1152/ajpregu.1991.261.2.r473
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 260:H985-H988
The purpose of this study was to quantify the relative roles of the canine cardiac parasympathetic and sympathetic nerves in controlling the distribution of power within the heart rate (HR) power spectrum using a highly selective surgical technique t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c147ed37f8d2bbe4f606b494a938dee6
https://doi.org/10.1152/ajpheart.1991.260.3.h985
https://doi.org/10.1152/ajpheart.1991.260.3.h985
Publikováno v:
The American journal of physiology. 262(4 Pt 2)
Selective surgical sinoatrial (SA)-nodal parasympathectomy (PSX) was used to distinguish the role of the cardiac autonomic nerves in heart rate (HR) control in awake dogs (n = 8) during rest and behavioral arousal. Resting HR increased from 85 +/- 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc531f249c736b7da6f2442e69b0927
https://pubmed.ncbi.nlm.nih.gov/1566895
https://pubmed.ncbi.nlm.nih.gov/1566895
Publikováno v:
International journal of cardiology. 26(3)
The effect of neurogenic coronary vasomotor tone upon contraction in ischemic myocardium was investigated in awake, mongrel dogs. The animals were chronically instrumented with a hydraulic occluder around the left circumflex coronary artery; a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d25ea1be938d5f76b4e4bb9738b211
https://pubmed.ncbi.nlm.nih.gov/2155880
https://pubmed.ncbi.nlm.nih.gov/2155880
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 3(5)
The purpose of this experiment was to test the stability of the heart rate (HR) power spectrum over time in conscious dogs. HR was recorded for 1 h for each of six animals on 2 days. A Fast Fourier transform was used to derive the HR power spectrum f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8fff914c10641ba930bb46cde45bd5
https://pubmed.ncbi.nlm.nih.gov/2920878
https://pubmed.ncbi.nlm.nih.gov/2920878