Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jeffrey D. Rytlewski"'
Autor:
Wade R. Gutierrez, Jeffrey D. Rytlewski, Amanda Scherer, Grace A. Roughton, Nina C. Carnevale, Krisha Y. Vyas, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Rebecca D. Dodd
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1218-1232 (2023)
Rhabdomyosarcoma (RMS) is an aggressive form of cancer that accounts for half of all pediatric soft tissue sarcomas. Little progress has been made in improving survival outcomes over the past three decades. Mouse models of rhabdomyosarcoma are a crit
Externí odkaz:
https://doaj.org/article/aadfd4285500410b8d0e896539fe86c7
Low‐Cost, High‐Pressure‐Synthesized Oxygen‐Entrapping Materials to Improve Treatment of Solid Tumors
Autor:
Jianling Bi, Emily Witt, Vanessa A. Voltarelli, Vivian R. Feig, Veena Venkatachalam, Hannah Boyce, Megan McGovern, Wade R. Gutierrez, Jeffrey D. Rytlewski, Kate R. Bowman, Ashley C. Rhodes, Austin N. Cook, Benjamin N. Muller, Matthew G. Smith, Alexis Rebecca Ramos, Heena Panchal, Rebecca D. Dodd, Michael D. Henry, Adam Mailloux, Giovanni Traverso, Leo E. Otterbein, James D. Byrne
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Tumor hypoxia drives resistance to many cancer therapies, including radiotherapy and chemotherapy. Methods that increase tumor oxygen pressures, such as hyperbaric oxygen therapy and microbubble infusion, are utilized to improve the response
Externí odkaz:
https://doaj.org/article/8033b7f9c53848e996896b38f139de6d
Autor:
Wade R. Gutierrez, Amanda Scherer, Jeffrey D. Rytlewski, Emily A. Laverty, Alexa P. Sheehan, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Grace A. Roughton, Dawn E. Quelle, David J. Gordon, Varun Monga, Rebecca D. Dodd
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
The DNA methyltransferase inhibitor decitabine has classically been used to reactivate silenced genes and as a pretreatment for anticancer therapies. In a variation of this idea, this study explores the concept of adding low-dose decitabine (DAC) fol
Externí odkaz:
https://doaj.org/article/f1f2ba4470e1443796a237d00e963599
Autor:
Benjamin J. Miller, Munir R. Tanas, Varun Monga, Fatima Toor, Keith Garcia, Jeffrey D. Rytlewski, Mohammed M. Milhem, Bryan G. Allen, Nicholas Scalora
Publikováno v:
Cancers, Vol 13, Iss 675, p 675 (2021)
Cancers
Cancers
Simple Summary Advanced sarcomas have yet to undergo improved outcomes seen in other cancer subtypes. Verteporfin has the potential to show landmark change in sarcoma due to its anti-proliferative properties: inhibition of the Hippo pathway and as ph
Autor:
Alexander L Kuzma, Paul Childress, David C. Scofield, Todd O. McKinley, Roman M. Natoli, Tien-Min G. Chu, Rashad H. Usmani, Jeffrey D Rytlewski, Emily Jewell, Jeffrey O. Anglen, James P. Fischer, Kaitlyn S. Griffin, Melissa A. Kacena, Karl D Shively
Publikováno v:
Mil Med
Background and Objective Porcine translational models have become the gold-standard translational tool to study the effects of major injury and hemorrhagic shock because of their similarity to the human immunologic response to trauma. Segmental bone
Autor:
Yasaman Shirazi-Fard, Cynthia-May S. Gong, Sungshin Y. Choi, David C. Scofield, David J. Olivos, Jonathan S. Harris, Paul Childress, Todd O. McKinley, Rasha Hammamieh, Alexander Brinker, Carolynn L. Conley, Tien-Min G. Chu, Melissa A. Kacena, Nabarun Chakraborty, Jeffrey D. Rytlewski
Publikováno v:
Life Sciences in Space Research. 16:52-62
Segmental bone defects (SBDs) secondary to trauma invariably result in a prolonged recovery with an extended period of limited weight bearing on the affected limb. Soldiers sustaining blast injuries and civilians sustaining high energy trauma typify
Autor:
Jeffrey D, Rytlewski, Paul J, Childress, David C, Scofield, Faisal, Khan, Marta B, Alvarez, Aamir T, Tucker, Jonathan S, Harris, Jessica L, Peveler, Debra L, Hickman, Tien-Min G, Chu, Melissa A, Kacena
Publikováno v:
Comparative medicine. 68(2)
Spaceflight results in bone loss like that associated with osteoporosis or decreased weight-bearing (for example, high-energy trauma such as explosive injuries and automobile accidents). Thus, the unique spaceflight laboratory on the International Sp
Autor:
Jessica L Peveler, Paul Childress, David C. Scofield, Jeffrey D. Rytlewski, Kishan M. Shah, Melissa A. Kacena, Aamir Tucker, Tien-Min G. Chu, Todd O. McKinley, Ding Li, Faisal Khan, Debra L. Hickman
Publikováno v:
Life sciences in space research. 17
This study was initiated as a component of a larger undertaking designed to study bone healing in microgravity aboard the International Space Station (ISS). Spaceflight experimentation introduces multiple challenges not seen in ground studies, especi