Výsledky vyhledávání - "Jeffrey D. Fay"

Selenoprotein K regulation of palmitoylation and calpain cleavage of ASAP2 is required for efficient FcγR-mediated phagocytosis

Autor: Peter R. Hoffmann, Zhi Huang, FuKun W. Hoffmann, Robert L. Norton, Jeffrey D. Fay, Gregory J. Fredericks

Publikováno v: Journal of Leukocyte Biology. 101:439-448

Effective activation of macrophages through phagocytic Fcγ receptors (FcγR) has been shown to require selenoprotein K (Selk). We set out to determine whether the FcγR-mediated uptake process itself also requires Selk and potential underlying mecha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ee6d9ec10ee1107795da75a2f99d9c
https://doi.org/10.1189/jlb.2a0316-156rr

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Stimulation of Unprimed Macrophages with Immune Complexes Triggers a Low Output of Nitric Oxide by Calcium-dependent Neuronal Nitric-oxide Synthase

Autor: Moti L. Chapagain, Zhi Huang, Peter R. Hoffmann, Jeffrey D. Fay, FuKun W. Hoffmann, Ann C. Hashimoto, Pakieli H. Kaufusi

Publikováno v: Journal of Biological Chemistry. 287:4492-4502

Immune complexes composed of IgG-opsonized pathogens, particles, or proteins are phagocytosed by macrophages through Fcγ receptors (FcγRs). Macrophages primed with IFNγ or other pro-inflammatory mediators respond to FcγR engagement by secreting h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937741e951335e4b70adafd3f0c4e282
https://doi.org/10.1074/jbc.m111.315598

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