Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Jeffrey D. Clogston"'
Autor:
Hannah S. Newton, Jenny Zhang, Duncan Donohue, Ragi Unnithan, Edward Cedrone, Jie Xu, Alison Vermilya, Tyler Malys, Jeffrey D. Clogston, Marina A. Dobrovolskaia
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionImmunophenotyping, which is the identification of immune cell subsets based on antigen expression, is an integral technique used to determine changes of cell composition and activation in various disease states or as a response to differe
Externí odkaz:
https://doaj.org/article/bd774b4beec14b8db17cb8ee2017a52b
Autor:
Hannah S. Newton, Yasmine Radwan, Jie Xu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Kirill A. Afonin
Publikováno v:
Molecules, Vol 28, Iss 11, p 4484 (2023)
Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimulati
Externí odkaz:
https://doaj.org/article/534ab500d97042b2b738b10d4b85f16f
Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier
Autor:
Yelixza I. Avila, Morgan Chandler, Edward Cedrone, Hannah S. Newton, Melina Richardson, Jie Xu, Jeffrey D. Clogston, Neill J. Liptrott, Kirill A. Afonin, Marina A. Dobrovolskaia
Publikováno v:
Molecules, Vol 26, Iss 3, p 652 (2021)
Recent insights into the immunostimulatory properties of nucleic acid nanoparticles (NANPs) have demonstrated that variations in the shape, size, and composition lead to distinct patterns in their immunostimulatory properties. While most of these stu
Externí odkaz:
https://doaj.org/article/8f16ade319414daab6b20f4ae0003a4a
Autor:
Edward Cedrone, Barry W. Neun, Jamie Rodriguez, Alison Vermilya, Jeffrey D. Clogston, Scott E. McNeil, Yechezkel Barenholz, Janos Szebeni, Marina A. Dobrovolskaia
Publikováno v:
Molecules, Vol 23, Iss 1, p 12 (2017)
The preclinical safety assessment of novel nanotechnology-based drug products frequently relies on in vitro assays, especially during the early stages of product development, due to the limited quantities of nanomaterials available for such studies.
Externí odkaz:
https://doaj.org/article/7af0fd1578c248ba9013c602b4599551
Autor:
Afonin, Hannah S. Newton, Yasmine Radwan, Jie Xu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Kirill A.
Publikováno v:
Molecules; Volume 28; Issue 11; Pages: 4484
Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimulati
Autor:
Thomas V. O'Halloran, Vincent L. Cryns, Vamsi Parimi, Elden P. Swindell, Meera R. Raja, Anil K. Patri, Jeffrey D. Clogston, Stephan T. Stern, Haimei Chen, Feng Chen, Richard W. Ahn
Supplementary Data from A Novel Nanoparticulate Formulation of Arsenic Trioxide with Enhanced Therapeutic Efficacy in a Murine Model of Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4450b1fd859cb0b60dfcf9cb1811821b
https://doi.org/10.1158/1078-0432.22442936
https://doi.org/10.1158/1078-0432.22442936
Autor:
Thomas V. O'Halloran, Vincent L. Cryns, Vamsi Parimi, Elden P. Swindell, Meera R. Raja, Anil K. Patri, Jeffrey D. Clogston, Stephan T. Stern, Haimei Chen, Feng Chen, Richard W. Ahn
Purpose: The clinical success of arsenic trioxide (As2O3) in hematologic malignancies has not been replicated in solid tumors due to poor pharmacokinetics and dose-limiting toxicity. We have developed a novel nanoparticulate formulation of As2O3 enca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff2b9bd930deb0bb614fcd828ebe35
https://doi.org/10.1158/1078-0432.c.6519557.v1
https://doi.org/10.1158/1078-0432.c.6519557.v1
Autor:
Jeffrey D. Clogston
Publikováno v:
Advanced drug delivery reviews. 176
Physicochemical characterization of nanoparticles intended for immunology research is important as it helps explain the observed immunological effects. More importantly, it relates the physicochemical properties with the immunological properties to d
Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier
Autor:
Neill J. Liptrott, Edward Cedrone, Morgan Chandler, Jeffrey D. Clogston, Jie Xu, Yelixza I Avila, Melina Richardson, Kirill A. Afonin, Hannah S Newton, Marina A. Dobrovolskaia
Publikováno v:
MOLECULES
Molecules, Vol 26, Iss 652, p 652 (2021)
Molecules
Volume 26
Issue 3
Molecules, Vol 26, Iss 652, p 652 (2021)
Molecules
Volume 26
Issue 3
Recent insights into the immunostimulatory properties of nucleic acid nanoparticles (NANPs) have demonstrated that variations in the shape, size, and composition lead to distinct patterns in their immunostimulatory properties. While most of these stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc42e2f97cb3b69eae725cb6a5c50505
Autor:
Jeffrey D. Clogston, Siva Sai Krishna Dasa, Rachael M. Crist, Stephan T. Stern, Marina A. Dobrovolskaia, Christina H. Liu
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 13
Despite imaging agents being some of the earliest nanomedicines in clinical use, the vast majority of current research and translational activities in the nanomedicine field involves therapeutics, while imaging agents are severely underrepresented. T