Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jeffrey D Messinger"'
Autor:
Lan Wang, Mark E Clark, David K Crossman, Kyoko Kojima, Jeffrey D Messinger, James A Mobley, Christine A Curcio
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10329 (2010)
Drusen are extracellular lesions characteristic of aging and age-related maculopathy, a major retinal disease of the elderly. We determined the relative proportions of lipids and proteins in drusen capped with retinal pigment epithelium (RPE) and in
Externí odkaz:
https://doaj.org/article/a92ed5ba3a024591b0c57fe13eedc561
Autor:
David M. G. Anderson, Ankita Kotnala, Lukasz G. Migas, N. Heath Patterson, Léonore E. M. Tideman, Dongfeng Cao, Bibek Adhikari, Jeffrey D. Messinger, Thomas Ach, Sara Tortorella, Raf Van de Plas, Christine A. Curcio, Kevin L. Schey
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
IntroductionAge related macular degeneration (AMD) causes legal blindness worldwide, with few therapeutic targets in early disease and no treatments for 80% of cases. Extracellular deposits, including drusen and subretinal drusenoid deposits (SDD; al
Externí odkaz:
https://doaj.org/article/26cf13097cc94e109442e9a1e0f3b623
Autor:
Andreas Berlin, MD, MS, Diogo Cabral, MD, Ling Chen, MD, PhD, Jeffrey D. Messinger, DC, Chandrakumar Balaratnasingam, MD, PhD, Randev Mendis, MD, Daniela Ferrara, MD, PhD, K. Bailey Freund, MD, Christine A. Curcio, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100280- (2023)
Purpose: To investigate intraretinal neovascularization and microvascular anomalies by correlating in vivo multimodal imaging with corresponding ex vivo histology in a single patient. Design: A case study comprising clinical imaging from a community-
Externí odkaz:
https://doaj.org/article/198921117a03433db244ff39bc698b04
Autor:
Siyu Chen, PhD, Omar Abu-Qamar, MD, MMSc, Deepayan Kar, MS, Jeffrey D. Messinger, DC, Yunchan Hwang, Eric M. Moult, PhD, Junhong Lin, Caroline R. Baumal, MD, Andre Witkin, MD, Michelle C. Liang, MD, Nadia K. Waheed, MD, MPH, Christine A. Curcio, PhD, James G. Fujimoto, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100277- (2023)
Purpose: Ultrahigh resolution spectral domain-OCT (UHR SD-OCT) enables in vivo visualization of micrometric structural markers which differentially associate with normal aging versus age-related macular degeneration (AMD). This study explores the hyp
Externí odkaz:
https://doaj.org/article/6f0d28feddbd440783d6fa287661e1e4
Autor:
Max Brinkmann, Tommaso Bacci, Deepayan Kar, Jeffrey D. Messinger, Kenneth R. Sloan, Ling Chen, Timothy Hamann, Maximilian Wiest, K. Bailey Freund, Sandrine Zweifel, Christine A. Curcio
Publikováno v:
American Journal of Ophthalmology. 240:99-114
To evaluate hypotheses about the role of acquired vitelliform lesion (AVL) in age-related macular degeneration pathophysiology.Laboratory histology study; retrospective, observational case series.Two donor eyes in a research archive with AVL and age-
Autor:
Jeffrey D. Messinger, Max Brinkmann, James A. Kimble, Andreas Berlin, K. Bailey Freund, Gregory H. Grossman, Thomas Ach, Christine A. Curcio
Publikováno v:
Journal of Visualized Experiments.
Autor:
Jeffrey D. Messinger
The accession and fixation of whole human eye specimens at University of Alabama Birmingham as part of the Human Biomolecular Atlas Project.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3cb52b18299349df61a2facbb1ef93
https://doi.org/10.17504/protocols.io.8epv5jp75l1b/v1
https://doi.org/10.17504/protocols.io.8epv5jp75l1b/v1
Publikováno v:
Ophthalmol Retina
Purpose Macular atrophy (MA) of retinal pigment epithelium (RPE) and photoreceptors leads to vision loss in neovascular age-related macular degeneration (nAMD) despite successful treatment with antiangiogenic agents. To enhance understanding of MA, f
Autor:
Andreas Berlin, Diogo Cabral, Ling Chen, Jeffrey D Messinger, Chandrakumar Balaratnasingam, Randev Mendis, Daniela Ferrara, K. Bailey Freund, Christine A Curcio
Objective/PurposeTo investigate intraretinal neovascularization and microvascular anomalies by correlating in vivo multimodal imaging with corresponding ex vivo histology in a single patient.DesignA case study comprising clinical imaging from a commu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a9996ccb046ac975ab08c491f80e50
https://doi.org/10.1101/2022.09.13.22279910
https://doi.org/10.1101/2022.09.13.22279910
Autor:
Jeffrey D. Messinger, Jost Hillenkamp, Andreas Berlin, Pia Stockinger, Christine Schmitt, Daniel Kampik, Thomas Ach, Martina C. Herwig-Carl
Publikováno v:
Der Ophthalmologe. 117:1188-1195
Fur das pathologische Verstandnis retinaler Veranderungen sind direkte Vergleiche von hochaufgeloster In-vivo-Bildgebung und histologischer Darstellung wunschenswert. Dargestellt wird der methodische Aufbau zur multimodalen In-vivo- und Ex-vivo-Bildg