Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Jeffrey D Hartgerink"'
Autor:
Minh Phuong Dong, Neeraja Dharmaraj, Estela Kaminagakura, Jianfei Xue, David G. Leach, Jeffrey D. Hartgerink, Michael Zhang, Hana-Joy Hanks, Yi Ye, Bradley E. Aouizerat, Kyle Vining, Carissa M. Thomas, Sinisa Dovat, Simon Young, Chi T. Viet
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 920 (2024)
Oral squamous cell carcinoma (OSCC) presents significant treatment challenges due to its poor survival and intense pain at the primary cancer site. Cancer pain is debilitating, contributes to diminished quality of life, and causes opioid tolerance. T
Externí odkaz:
https://doaj.org/article/6e08a52ce46a4c4ebfc4aafaca817580
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release. These self-assembling peptides can form diverse n
Externí odkaz:
https://doaj.org/article/f3e5a7da7bf0451f8d985757625f13a2
Autor:
Ravi Murthy, Alda Tam, Nina M. Muñoz, Malea Williams, Katherine Dixon, Crystal Dupuis, Amanda McWatters, Rony Avritscher, Soraya Zorro Manrique, Kevin McHugh, David Leach, Jeffrey D. Hartgerink, Punit Prakash, Rahul A. Sheth
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Intratumoral delivery of immunotherapeutics represents a compelling solution to directly address local barriers to tumor immunity. However, we have previously shown that off-target delivery is a substantial problem during intratumoral inje
Externí odkaz:
https://doaj.org/article/7f53a27182084eda9d4c4b3cba2d5e18
Autor:
Brett H. Pogostin, Gabriel Saenz, Carson C. Cole, Erin M. Euliano, Jeffrey D. Hartgerink, Kevin J. McHugh
Publikováno v:
Bioconjugate Chemistry. 34:193-203
Recently, there has been increased interest in using mannan as an immunomodulatory bioconjugate. Despite notable immunological and functional differences between the reduced (R-Man) and oxidized (O-Man) forms of mannan, little is known about the impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35c0be04ee440afd2cc2f3470cbd4da
https://doi.org/10.1021/acs.bioconjchem.2c00461
https://doi.org/10.1021/acs.bioconjchem.2c00461
Autor:
Cheuk Sun Edwin Lai, Viridiana Leyva-Aranda, Victoria H. Kong, Tania L. Lopez-Silva, Adam C. Farsheed, Carlo D. Cristobal, Joseph W. R. Swain, Hyun Kyoung Lee, Jeffrey D. Hartgerink
Publikováno v:
ACS Applied Bio Materials. 5:4611-4624
Transected peripheral nerve injury (PNI) affects the quality of life of patients, which leads to socioeconomic burden. Despite the existence of autografts and commercially available nerve guidance conduits (NGCs), the complexity of peripheral nerve r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ead43e186c29433243dcc39b4e32d6f
https://doi.org/10.1021/acsabm.2c00132
https://doi.org/10.1021/acsabm.2c00132
A wireless millimetric magnetoelectric implant for the endovascular stimulation of peripheral nerves
Autor:
Joshua C. Chen, Peter Kan, Zhanghao Yu, Fatima Alrashdan, Roberto Garcia, Amanda Singer, C. S. Edwin Lai, Ben Avants, Scott Crosby, Zhongxi Li, Boshuo Wang, Michelle M. Felicella, Ariadna Robledo, Angel V. Peterchev, Stefan M. Goetz, Jeffrey D. Hartgerink, Sunil A. Sheth, Kaiyuan Yang, Jacob T. Robinson
Publikováno v:
Nature Biomedical Engineering. 6:706-716
Funder: NIH U18EB029353, NSF GRFP
Funder: NIH U18EB029353
Funder: NIH R01DE021798, NSF GRFP
Funder: NIH R01DE021798
Implantable bioelectronic devices for the simulation of peripheral nerves could be used to treat disorders that ar
Funder: NIH U18EB029353
Funder: NIH R01DE021798, NSF GRFP
Funder: NIH R01DE021798
Implantable bioelectronic devices for the simulation of peripheral nerves could be used to treat disorders that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300cf77b8d6d0c33b9faae795fb4caff
https://doi.org/10.1038/s41551-022-00873-7
https://doi.org/10.1038/s41551-022-00873-7
Publikováno v:
Biomacromolecules. 23:1475-1489
Collagen mimetic peptides (CMPs) fold into a polyproline type II triple helix, allowing the study of the structure and function (or misfunction) of the collagen family of proteins. This Perspective will focus on recent developments in the use of CMPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7387bcde0f310e39d2d6f681453a6baa
https://doi.org/10.1021/acs.biomac.2c00028
https://doi.org/10.1021/acs.biomac.2c00028
Autor:
Brett H. Pogostin, Marina H. Yu, Alon R. Azares, Erin M. Euliano, Cheuk Sun Edwin Lai, Gabriel Saenz, Samuel X. Wu, Adam C. Farsheed, Sarah M. Melhorn, Tyler P. Graf, Darren G. Woodside, Jeffrey D. Hartgerink, Kevin J. McHugh
Publikováno v:
Biomaterials Science. 10:6217-6229
Adjuvants play a critical role in enhancing vaccine efficacy; however, there is a need to develop new immunomodulatory compounds to address emerging pathogens and to expand the use of immunotherapies. Multidomain peptides (MDPs) are materials compose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c39e502416ded4f2b124d5ca1429df8
https://doi.org/10.1039/d2bm01242a
https://doi.org/10.1039/d2bm01242a
Publikováno v:
Advanced materials (Deerfield Beach, Fla.).
3D printing has become one of the primary fabrication strategies used in biomedical research. Recent efforts have focused on the 3D printing of hydrogels to create structures that better replicate the mechanical properties of biological tissues. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3646507618e5587ec61b78d5364973
https://pubmed.ncbi.nlm.nih.gov/36604310
https://pubmed.ncbi.nlm.nih.gov/36604310
Autor:
Carson C. Cole, Mikita Misiura, Sarah A. H. Hulgan, Caroline M. Peterson, Joseph W. Williams, Anatoly B. Kolomeisky, Jeffrey D. Hartgerink
Publikováno v:
Biomacromolecules. 23(11)
Cation-π interactions play a significant role in the stabilization of globular proteins. However, their role in collagen triple helices is less well understood and they have rarely been used in de novo designed collagen mimetic systems. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe348dbede3be735213dd31e08d700e
https://pubmed.ncbi.nlm.nih.gov/36239387
https://pubmed.ncbi.nlm.nih.gov/36239387