Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jeffrey D Clogston"'
Autor:
Anthony O. Omole, Jessica Fernanda Affonso de Oliveira, Lucas Sutorus, Sweta Karan, Zhongchao Zhao, Barry W. Neun, Edward Cedrone, Jeffrey D. Clogston, Jie Xu, Michael Sierk, Qingrong Chen, Daoud Meerzaman, Marina A. Dobrovolskaia, Nicole F. Steinmetz
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Cowpea mosaic virus (CPMV) is a plant virus that is currently being developed for intratumoral immunotherapy. CPMV relieves the immune system from tumor-induced immunosuppression; reprograms the tumor microenvironment to an activated state w
Externí odkaz:
https://doaj.org/article/955d052da3a7445295e96ab270f67690
Autor:
Monique P Gelderman, Olga Simakova, Jeffrey D Clogston, Anil K Patri, Sheena F Siddiqui, et al
Publikováno v:
International Journal of Nanomedicine, Vol 2008, Iss Issue 1, Pp 59-68 (2008)
Monique P Gelderman1, Olga Simakova2, Jeffrey D Clogston3, Anil K Patri3, Sheena F Siddiqui1, Alexander C Vostal1, Jan Simak11CBER, FDA, Rockville, MD, USA; 2School of Medicine, USUHS, Bethesda, MD, USA; 3Nanotechnology Characterization Lab, Advanced
Externí odkaz:
https://doaj.org/article/98ec3433c80847bf919c872329341cbe
Autor:
Hannah S. Newton, Jenny Zhang, Duncan Donohue, Ragi Unnithan, Edward Cedrone, Jie Xu, Alison Vermilya, Tyler Malys, Jeffrey D. Clogston, Marina A. Dobrovolskaia
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
IntroductionImmunophenotyping, which is the identification of immune cell subsets based on antigen expression, is an integral technique used to determine changes of cell composition and activation in various disease states or as a response to differe
Externí odkaz:
https://doaj.org/article/bd774b4beec14b8db17cb8ee2017a52b
Autor:
Hannah S. Newton, Yasmine Radwan, Jie Xu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Kirill A. Afonin
Publikováno v:
Molecules, Vol 28, Iss 11, p 4484 (2023)
Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimulati
Externí odkaz:
https://doaj.org/article/534ab500d97042b2b738b10d4b85f16f
Autor:
Afonin, Hannah S. Newton, Yasmine Radwan, Jie Xu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Kirill A.
Publikováno v:
Molecules; Volume 28; Issue 11; Pages: 4484
Nucleic acid nanoparticles (NANPs) require a carrier to allow for their intracellular delivery to immune cells. Cytokine production, specifically type I and III interferons, allows for reliable monitoring of the carrier effect on NANP immunostimulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::a6c6a4ca875ab54b540a7ca40e588d08
Autor:
Thomas V. O'Halloran, Vincent L. Cryns, Vamsi Parimi, Elden P. Swindell, Meera R. Raja, Anil K. Patri, Jeffrey D. Clogston, Stephan T. Stern, Haimei Chen, Feng Chen, Richard W. Ahn
Purpose: The clinical success of arsenic trioxide (As2O3) in hematologic malignancies has not been replicated in solid tumors due to poor pharmacokinetics and dose-limiting toxicity. We have developed a novel nanoparticulate formulation of As2O3 enca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97ff2b9bd930deb0bb614fcd828ebe35
https://doi.org/10.1158/1078-0432.c.6519557.v1
https://doi.org/10.1158/1078-0432.c.6519557.v1
Autor:
Edward Cedrone, Barry W. Neun, Jamie Rodriguez, Alison Vermilya, Jeffrey D. Clogston, Scott E. McNeil, Yechezkel Barenholz, Janos Szebeni, Marina A. Dobrovolskaia
Publikováno v:
Molecules, Vol 23, Iss 1, p 12 (2017)
The preclinical safety assessment of novel nanotechnology-based drug products frequently relies on in vitro assays, especially during the early stages of product development, due to the limited quantities of nanomaterials available for such studies.
Externí odkaz:
https://doaj.org/article/7af0fd1578c248ba9013c602b4599551
Autor:
Jeffrey D. Clogston
Publikováno v:
Advanced drug delivery reviews. 176
Physicochemical characterization of nanoparticles intended for immunology research is important as it helps explain the observed immunological effects. More importantly, it relates the physicochemical properties with the immunological properties to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7900530b5269d4cd0ec5cc2fcf48245c
https://pubmed.ncbi.nlm.nih.gov/34314786
https://pubmed.ncbi.nlm.nih.gov/34314786
Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier
Autor:
Neill J. Liptrott, Edward Cedrone, Morgan Chandler, Jeffrey D. Clogston, Jie Xu, Yelixza I Avila, Melina Richardson, Kirill A. Afonin, Hannah S Newton, Marina A. Dobrovolskaia
Publikováno v:
MOLECULES
Molecules, Vol 26, Iss 652, p 652 (2021)
Molecules
Volume 26
Issue 3
Molecules, Vol 26, Iss 652, p 652 (2021)
Molecules
Volume 26
Issue 3
Recent insights into the immunostimulatory properties of nucleic acid nanoparticles (NANPs) have demonstrated that variations in the shape, size, and composition lead to distinct patterns in their immunostimulatory properties. While most of these stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc42e2f97cb3b69eae725cb6a5c50505
Autor:
Jeffrey D. Clogston, Siva Sai Krishna Dasa, Rachael M. Crist, Stephan T. Stern, Marina A. Dobrovolskaia, Christina H. Liu
Publikováno v:
WIREs Nanomedicine and Nanobiotechnology. 13
Despite imaging agents being some of the earliest nanomedicines in clinical use, the vast majority of current research and translational activities in the nanomedicine field involves therapeutics, while imaging agents are severely underrepresented. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149e1368914066d8b6b35fd1c0ed2b02
https://doi.org/10.1002/wnan.1665
https://doi.org/10.1002/wnan.1665