Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Jeffrey D, Long"'
Autor:
Allan Andersen, Emily Milefchik, Emma Papworth, Brandan Penaluna, Kelsey Dawes, Joanna Moody, Gracie Weeks, Ellyse Froehlich, Kaitlyn deBlois, Jeffrey D Long, Robert Philibert
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTCurrently, clinicians use their judgement and indices such as the Prediction of Alcohol Withdrawal Syndrome Scale (PAWSS) to determine whether patients are admitted to hospitals for consideration of withdrawal syndrome (AWS). However, only a
Externí odkaz:
https://doaj.org/article/a64aec19b5b6469f9f6cb17181799700
Autor:
Sergey V. Lobanov, Branduff McAllister, Mia McDade-Kumar, G. Bernhard Landwehrmeyer, Michael Orth, Anne E. Rosser, REGISTRY Investigators of the European Huntington’s disease network, Jane S. Paulsen, PREDICT-HD Investigators of the Huntington Study Group, Jong-Min Lee, Marcy E. MacDonald, James F. Gusella, Jeffrey D. Long, Mina Ryten, Nigel M. Williams, Peter Holmans, Thomas H. Massey, Lesley Jones
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Huntington’s disease is caused by an expanded CAG tract in HTT. The length of the CAG tract accounts for over half the variance in age at onset of disease, and is influenced by other genetic factors, mostly implicating the DNA maintenance
Externí odkaz:
https://doaj.org/article/471abbf3af654a65a0a60f88b8f7af52
Autor:
Arshaq Saleem, Gail Harmata, Shivangi Jain, Michelle W. Voss, Jess G. Fiedorowicz, Aislinn J. Williams, Joseph J. Shaffer, Jenny Gringer Richards, Ercole John Barsotti, Leela Sathyaputri, Samantha L. Schmitz, Gary E. Christensen, Jeffrey D. Long, Jia Xu, John A. Wemmie, Vincent A. Magnotta
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
PurposeStudies of the neural underpinnings of bipolar type I disorder have focused on the emotional control network. However, there is also growing evidence for cerebellar involvement, including abnormal structure, function, and metabolism. Here, we
Externí odkaz:
https://doaj.org/article/cd31c1c6415a430790377dc92c1b8721
Autor:
Allan Andersen, Rachel Reimer, Kelsey Dawes, Ashley Becker, Natasha Hutchens, Shelly Miller, Meesha Dogan, Brandon Hundley, James A Mills, Jeffrey D Long, Robert Philibert
Publikováno v:
Epigenetics, Vol 17, Iss 2, Pp 178-190 (2022)
Increasing use of non-combusted forms of nicotine such as e-cigarettes poses important public health questions regarding their specific risks relative to combusted tobacco products such as cigarettes. To fully delineate these risks, improved biomarke
Externí odkaz:
https://doaj.org/article/ea0c7fafefc443139b66c44813b50a2c
Autor:
Jinnie Ko, Hannah Furby, Xiaoye Ma, Jeffrey D. Long, Xiao-Yu Lu, Diana Slowiejko, Rita Gandhy
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
IntroductionHuntington's disease (HD) is a rare neurodegenerative disease characterized by cognitive, behavioral and motor symptoms that progressively worsen with time. Cognitive and behavioral signs of HD are generally present in the years prior to
Externí odkaz:
https://doaj.org/article/07ebbb7c09244b79bb6b1519608b33e6
Autor:
Kelsey Dawes, Allan Andersen, Rachel Reimer, James A. Mills, Eric Hoffman, Jeffrey D. Long, Shelly Miller, Robert Philibert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Numerous studies have shown that cg05575921 methylation decreases in response to smoking. However, secondary to methodological issues, the magnitude and dose dependency of that response is as of yet unclear. This lack of certainty is a barri
Externí odkaz:
https://doaj.org/article/f9a2397189974920a5250144371a2f3c
Autor:
Robert Philibert, Jeffrey D. Long, James A. Mills, S. R. H. Beach, Frederick X. Gibbons, Meg Gerrard, Ron Simons, Paulo B. Pinho, Douglas Ingle, Kelsey Dawes, Timur Dogan, Meeshanthini Dogan
Publikováno v:
Epigenetics, Vol 16, Iss 10, Pp 1135-1149 (2021)
Mortality assessments are conducted for both civil and commercial purposes. Recent advances in epigenetics have resulted in DNA methylation tools to assess risk and aid in this task. However, widely available array-based algorithms are not readily tr
Externí odkaz:
https://doaj.org/article/72120a33dd11423ab44ed7d7046c9150
Autor:
Ellen van der Plas, Jeffrey D. Long, Timothy R. Koscik, Vincent Magnotta, Darren G. Monckton, Sarah A. Cumming, Amy C. Gottschalk, Marco Hefti, Laurie Gutmann, Peggy C. Nopoulos
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
IntroductionThe present study had four aims. First, neuronal injury markers, including neurofilament light (NF-L), total tau, glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase (UCH-L1), were compared between individuals with a
Externí odkaz:
https://doaj.org/article/009018d5ab65499fb8768c4ab0e95700
Autor:
Ying Zhang, Junyi Zhou, Carissa R. Gehl, Jeffrey D. Long, Hans Johnson, Vincent A. Magnotta, Daniel Sewell, Kathleen Shannon, Jane S. Paulsen
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
As one of the clinical triad in Huntington's disease (HD), cognitive impairment has not been widely accepted as a disease stage indicator in HD literature. This work aims to study cognitive impairment thoroughly for prodromal HD individuals with the
Externí odkaz:
https://doaj.org/article/6c4b5b9559ff4e88b8065a07bd9b7360
Autor:
Jeffrey D. Long, Emily C. Gantman, James A. Mills, Jatin G. Vaidya, Alexandra Mansbach, Sarah J. Tabrizi, Cristina Sampaio
Publikováno v:
Journal of Huntington's Disease. 12:57-69
Background: The Huntington’s Disease Integrated Staging System (HD-ISS) has four stages that characterize disease progression. Classification is based on CAG length as a marker of Huntington’s disease (Stage 0), striatum atrophy as a biomarker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ff1e30383656ba02cc52f417fd04424
https://doi.org/10.3233/jhd-220555
https://doi.org/10.3233/jhd-220555