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pro vyhledávání: '"Jeffrey Colbeck"'
Autor:
Johan A. Kers, Sheela Muley, Jeffrey Colbeck, Melissa Mayo, R. Eryl Sharp, Jae H. Park, Anthony W. Defusco, Yihui Zhu, Martin Handfield
Publikováno v:
Chemical biologydrug design. 92(6)
Lantibiotics represent a large untapped pipeline of attractive scaffolds for the development of novel antibiotics. Saturation mutagenesis was employed to substitute every amino acid of a lantibiotic called mutacin 1140 (MU1140), creating an unbiased
Autor:
Johan A. Kers, R. Eryl Sharp, Sheela Muley, Melissa Mayo, Jeffrey Colbeck, Yihui Zhu, Anthony W. DeFusco, Jae H. Park, Martin Handfield
Publikováno v:
Chemical Biology & Drug Design. 92:i-i
Autor:
Jacob M. Janey, Jeffrey Colbeck, William R. Jarvis, Sarena Tam, Gjalt W. Huisman, Emily Mundorff, Paul N. Devine, Jeffrey C. Moore, Anke Krebber, Jos Brands, Christopher Savile, Fred J. Fleitz, Gregory Hughes
Publikováno v:
Science. 329:305-309
Biocatalytic Boost Enzymes tend to direct reactions toward specific products much more selectively than synthetic catalysts. Unfortunately, this selectivity has evolved for cellular purposes and may not promote the sorts of reactions chemists are see