Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jeffrey Chavin"'
Autor:
Giancarlo Comi, Mark S. Freedman, José E. Meca-Lallana, Patrick Vermersch, Byoung Joon Kim, Alexander Parajeles, Keith R. Edwards, Ralf Gold, Houari Korideck, Jeffrey Chavin, Elizabeth M. Poole, Patricia K. Coyle
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background In this pooled, post hoc analysis of a phase 2 trial and the phase 3 TEMSO, TOWER, and TENERE clinical trials, long-term efficacy and safety of teriflunomide were assessed in subgroups of patients with relapsing multiple sclerosis
Externí odkaz:
https://doaj.org/article/1cd21d4c6c73407a8b8c61321663ae51
Autor:
Carlo Tornatore, Heinz Wiendl, Alex L. Lublin, Svend S. Geertsen, Jeffrey Chavin, Philippe Truffinet, Amit Bar-Or
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Many patients with multiple sclerosis (MS) receive disease-modifying therapies (DMTs), such as teriflunomide, to reduce disease activity and slow progression. DMTs mediate their efficacy by modulating or suppressing the immune system, which might aff
Externí odkaz:
https://doaj.org/article/9718b568875848799e11d780229c71f8
Autor:
Regina, Berkovich, Donald, Negroski, Daniel, Wynn, Daniel, Sellers, Kristen G, Bzdek, Alex L, Lublin, Andreea M, Rawlings, Cuc, Quach, Danelle P, Wells, Melanie, Dumlao, Adriana, Bora, Anthony E, Ranno, Kevin Lin, Luo, Jeffrey, Chavin, Le H, Hua, Daniel, Becker
Publikováno v:
Multiple Sclerosis and Related Disorders. 70:104472
The prevalence of multiple sclerosis (MS) in older people is increasing due to population aging and availability of effective disease-modifying therapies (DMTs). Treating older people with MS is complicated by age-related and MS-related comorbidities
Autor:
Bhupendra O. Khatri, Matt Mandel, Kiren Kresa-Reahl, Chakkarin Burudpakdee, Keith R. Edwards, Jeffrey Chavin, Robert Zivadinov, Bianca Weinstock-Guttman, Karthinathan Thangavelu, Stanley Cohan, Michael G. Dwyer, Niels Bergsland
Publikováno v:
Journal of Comparative Effectiveness Research. 8:305-316
Aim: Head-to-head clinical trials of teriflunomide (TFM) versus dimethyl fumarate (DMF) have not been conducted. Objectives: To compare the real-world effectiveness of TFM versus DMF. Methods: Anonymized data were collected from patients with relapsi
Autor:
Jeffrey Chavin, Alexander Parajeles, Byoung Joon Kim, Elizabeth M. Poole, Patrick Vermersch, Ralf Gold, Keith R. Edwards, Mark S. Freedman, Houari Korideck, Giancarlo Comi, José Meca-Lallana, Patricia K. Coyle
Publikováno v:
BMC Neurology
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Neurology, Vol 20, Iss 1, Pp 1-9 (2020)
Background In this pooled, post hoc analysis of a phase 2 trial and the phase 3 TEMSO, TOWER, and TENERE clinical trials, long-term efficacy and safety of teriflunomide were assessed in subgroups of patients with relapsing multiple sclerosis (MS) def
Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells
Autor:
Igor J. Koralnik, Charlotte Nyblade, Jenna Morris-Love, Xin Dang, Jeffrey Chavin, Alex L. Lublin, Gretchen V. Gee, Bethany A. O'Hara, Barbara A. Hanson, Sheila A. Haley, Walter J. Atwood, Timothy J. Turner, Chris Nieves
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 18
Pages: 9809
International Journal of Molecular Sciences, Vol 22, Iss 9809, p 9809 (2021)
Volume 22
Issue 18
Pages: 9809
International Journal of Molecular Sciences, Vol 22, Iss 9809, p 9809 (2021)
Several classes of immunomodulators are used for treating relapsing-remitting multiple sclerosis (RRMS). Most of these disease-modifying therapies, except teriflunomide, carry the risk of progressive multifocal leukoencephalopathy (PML), a severely d
Autor:
Steven Jacobson, Jeffrey Chavin, Nyater Ngouth, Yoshimi Enose-Akahata, Matt Mandel, Timothy J. Turner, Joan Ohayon
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo test the hypothesis that teriflunomide can reduce ex vivo spontaneous proliferation of peripheral blood mononuclear cells (PBMCs) from patients with human T-cell lymphotropic virus type 1 (HTLV-1)–associated myelopathy/tropical spastic
Autor:
Stephanie Jurgensen, Myriam Benamor, Jeffrey Chavin, Christina D. Chambers, Sandra Vukusic, Pk Coyle, Elizabeth M. Poole, Philippe Truffinet
Publikováno v:
Revue Neurologique. 175:S93
Introduction Dans les etudes cliniques (EC), le teriflunomide n’a montre aucun signal de teratogenicite chez l’homme. Cependant, il est contre-indique pendant la grossesse en raison de la toxicite embryo-fœtale chez la rate et le lapin. Objectif