Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jeffrey Capers"'
Autor:
N. D. Abdullaev, Bakhtiyor Rasulev, M. A. Turabekova, M. G. Levkovich, Jeffrey Capers, Valentina I. Vinogradova, Shukhrat B. Rakhimov, Karl A. Werbovetz
Publikováno v:
Chemical Biology & Drug Design. 78:183-189
In vitro leishmanicidal activity of 16 N-benzylcytisine derivatives has been evaluated using Leishmania donovani axenic amastigotes. In general, halogen (bromo-, chloro-) derivatives appeared to be more toxic against parasites than their parent compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc7f7b897bffb0f0e49865cc2c83dc19
https://doi.org/10.1111/j.1747-0285.2011.01092.x
https://doi.org/10.1111/j.1747-0285.2011.01092.x
Publikováno v:
Phytotherapy Research. 25:1246-1249
Bioactivity-directed fractionation of the MeOH fraction of the extract of Mimulus bigelovii by means of an axenic Leishmania amastigote assay and chromatographic techniques resulted in the isolation of four C-geranyl flavanones, diplacone (1), 3′-O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a59f400088ffeda9ce93291a27b155b
https://doi.org/10.1002/ptr.3404
https://doi.org/10.1002/ptr.3404
Publikováno v:
Letters in Drug Design & Discovery. 5:69-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d89a8dffba586a29e9d439ffede8466
https://doi.org/10.2174/157018008783406697
https://doi.org/10.2174/157018008783406697
Autor:
Daniel A. Nichols, J. A. Vigilante, Jeffrey Capers, J. R. Dettmer, Apurba K. Bhattacharjee, J. V. Vo, Clare E. Gutteridge, Lucia Gerena, S. L. Patterson, Karl A. Werbovetz, C. B. Tillett
Publikováno v:
Medicinal Chemistry. 3:115-119
The antileishmanial and antimalarial activity of methoxy-substituted chalcones (1,3-diphenyl-2-propen-1-ones) is well established. The few analogs prepared to date where the 3-phenyl group is replaced by either a pyridine or naphthalene suggest these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3ddee87ab577647b751e4f51bd7cda
https://doi.org/10.2174/157340607780059530
https://doi.org/10.2174/157340607780059530
Autor:
Malakhat A, Turabekova, Valentina I, Vinogradova, Karl A, Werbovetz, Jeffrey, Capers, Bakhtiyor F, Rasulev, Mikhail G, Levkovich, Shukhrat B, Rakhimov, Nasrulla D, Abdullaev
Publikováno v:
Chemical biologydrug design. 78(1)
In vitro leishmanicidal activity of 16 N-benzylcytisine derivatives has been evaluated using Leishmania donovani axenic amastigotes. In general, halogen (bromo-, chloro-) derivatives appeared to be more toxic against parasites than their parent compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7942f7abfb4144b65d9a1ba186e3f231
https://pubmed.ncbi.nlm.nih.gov/21457471
https://pubmed.ncbi.nlm.nih.gov/21457471
Publikováno v:
Phytotherapy research : PTR. 25(8)
Bioactivity-directed fractionation of the MeOH fraction of the extract of Mimulus bigelovii by means of an axenic Leishmania amastigote assay and chromatographic techniques resulted in the isolation of four C-geranyl flavanones, diplacone (1), 3'-O-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba759710a0d14e9a28ce163c6bb7e3c0
https://pubmed.ncbi.nlm.nih.gov/21796699
https://pubmed.ncbi.nlm.nih.gov/21796699
Autor:
Jeffrey Capers, Karl A. Werbovetz, Denise M Cottrell, Manar M. Salem, Kate DeLuca-Fradley, Simon L. Croft
Publikováno v:
Bioorganicmedicinal chemistry. 12(11)
A series of 5-thiocyanatomethyl- and 5-alkyl-3-aryl-1,2,4-oxadiazoles were synthesized and evaluated for their activity against kinetoplastid parasites. Formation of the oxadiazole ring was accomplished through the reaction of benzamidoximes with acy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77e11ee827c71a837c8a0c96b11d5fd
https://pubmed.ncbi.nlm.nih.gov/15142541
https://pubmed.ncbi.nlm.nih.gov/15142541