Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jeffrey C. Hoyt"'
Autor:
Jenny Pattengill, Jeffrey C. Hoyt, Alp Umar, John M. Hayden, Richard A. Robbins, Grigory Horonenko, Clement Singarajah
Publikováno v:
Chest. 132:58-63
Rationale: The diagnosis of ventilator-associated pneumonia (VAP) can be difficult. Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1) has been reported to be elevated in BAL fluid from patients with VAP. Objectives: To evaluate the ut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e8a2f5cf89e4b4e7076dc9d2613336a
https://doi.org/10.1378/chest.06-2731
https://doi.org/10.1378/chest.06-2731
Autor:
Richard A. Robbins, Muhammad Kashif Raza, John M Hayden, Janelle G. Ballering, Jeffrey C. Hoyt
Publikováno v:
Experimental Lung Research. 32:15-26
Certain antibiotics possess anti-inflammatory properties and could potentially be used to treat inflammatory lung diseases associated with an influx of monocytes such as panbronchiolitis, asthma, cystic fibrosis, and bronchitis. Doxycycline is report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf7d72cfda256427932b62a172f53f2
https://doi.org/10.1080/01902140600691399
https://doi.org/10.1080/01902140600691399
Publikováno v:
The Journal of Immunology. 176:567-572
Many effective therapeutic agents exhibit effects that are different from their intended primary mode of action. Antibiotics such as doxycycline and erythromycin A are no exception. They also display anti-inflammatory activity. Using LA4 murine lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795fb09cbcf5c3b5c505b1b4a1bd7e20
https://doi.org/10.4049/jimmunol.176.1.567
https://doi.org/10.4049/jimmunol.176.1.567
Autor:
Jeffrey C. Hoyt, Dan K. Nelson, Richard A. Robbins, Sekiya Koyama, Etsuro Sato, Michael P. Habib, Jun Amano, Hiroki Numanami, Masayuki Haniuda, Jon L. Freels
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:613-619
Smoking is associated with lung inflammation and a protease-antiprotease imbalance. We previously reported that cigarette smoke extract (CSE) stimulates human lung fibroblasts to release chemotactic cytokines. We hypothesized that serine protease inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77e84ae4254eedd94e1f203f48e5d36
https://doi.org/10.1165/rcmb.2003-0113oc
https://doi.org/10.1165/rcmb.2003-0113oc
Autor:
Michael P. Habib, Richard A. Robbins, Jeffrey C. Hoyt, Masayuki Haniuda, Dan K. Nelson, Jon L. Freels, Jun Amano, Hiroki Numanami, Sekiya Koyama
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:239-244
Peroxynitrite, formed by nitric oxide and superoxide, has been shown to nitrate and reduce the function of proinflammatory proteins such as interleukin (IL)-8, monocyte chemoattractant protein-1, and eotaxin, but in contrast, to enhance the function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f77016262e207b9ac8e4090413bb247
https://doi.org/10.1165/rcmb.2002-0275oc
https://doi.org/10.1165/rcmb.2002-0275oc
Publikováno v:
Molecular Microbiology. 46:505-517
Summary Streptomyces viridifaciens MG456-hF10 produces the antibiotic valanimycin, a naturally occurring azoxy compound. Valanimycin is known to be derived from valine and serine with the intermediacy of isobutylamine and isobutylhydroxylamine, but l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b545b87fde861debe223476ef061cd0
https://doi.org/10.1046/j.1365-2958.2002.03169.x
https://doi.org/10.1046/j.1365-2958.2002.03169.x
Autor:
Jeffrey C. Hoyt, Richard A. Robbins
Publikováno v:
FEMS Microbiology Letters. 205:1-7
Many clinically effective therapeutic agents can exhibit localized and systemic effects that are manifestly different from their intended primary pharmacological mode of action. Macrolide antibiotics such as erythromycin and its derivatives are no ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b0f28d7a7fa8802c9cfd20b7afbff6
https://doi.org/10.1111/j.1574-6968.2001.tb10917.x
https://doi.org/10.1111/j.1574-6968.2001.tb10917.x
Autor:
Veronica K Robinson, Etsuro Sato, Jeffrey C. Hoyt, Richard A. Robbins, Sharon L. Camhi, Dan K. Nelson
Publikováno v:
Free Radical Biology and Medicine. 30:986-991
Peroxynitrite, formed by nitric oxide (NO) and superoxide, can alter protein function by nitrating amino acids such as tyrosine, cysteine, trytophan, or methionine. Inducible nitric oxide synthase (Type 2 NOS or iNOS) converts arginine to citrulline,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889b97ce0a15cc2438d1f9529d6865ea
https://doi.org/10.1016/s0891-5849(01)00489-0
https://doi.org/10.1016/s0891-5849(01)00489-0
Publikováno v:
Immunopharmacology. 48:217-221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ebfa7a505a84d8e19cc7ffcb7e156f
https://doi.org/10.1016/s0162-3109(00)00220-4
https://doi.org/10.1016/s0162-3109(00)00220-4
Publikováno v:
Journal of Allergy and Clinical Immunology. 106:117-123
Background: Bradykinin, a potent inflammatory peptide, is increased in the airways of allergic patients. Accompanying the elevated bradykinin levels are increases in both eosinophils and fibroblasts. Eotaxin, a potent eosinophil-specific chemotactic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b2da4db332865c9c67f560365ab151
https://doi.org/10.1067/mai.2000.107400
https://doi.org/10.1067/mai.2000.107400