Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jeffrey C. Davis"'
Autor:
Ahmed I Mahmoud, Francisco X Galdos, Katherine A Dinan, Mark P Jedrychowski, Jeffrey C Davis, Ana Vujic, Inbal Rachmin, Christian Shigley, James R Pancoast, Samuel Lee, Jennifer Hollister-Lock, Catherine M MacGillivray, Steven P Gygi, Douglas A Melton, Gordon C Weir, Richard T Lee
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204595 (2018)
The in vivo microenvironment of tissues provides myriad unique signals to cells. Thus, following isolation, many cell types change in culture, often preserving some but not all of their in vivo characteristics in culture. At least some of the in vivo
Externí odkaz:
https://doaj.org/article/105ba49f67b348fb8916c00f5caeeb50
Autor:
Barak Blum, Adam N Roose, Ornella Barrandon, René Maehr, Anthony C Arvanites, Lance S Davidow, Jeffrey C Davis, Quinn P Peterson, Lee L Rubin, Douglas A Melton
Publikováno v:
eLife, Vol 3 (2014)
Dysfunction or death of pancreatic β cells underlies both types of diabetes. This functional decline begins with β cell stress and de-differentiation. Current drugs for type 2 diabetes (T2D) lower blood glucose levels but they do not directly allev
Externí odkaz:
https://doaj.org/article/3ad5b45b82e84774b6e71116e7e9164d
Autor:
James R. Pancoast, Jennifer Hollister-Lock, Douglas A. Melton, Ahmed I. Mahmoud, Catherine MacGillivray, Francisco X Galdos, Richard T. Lee, Inbal Rachmin, Mark P. Jedrychowski, Gordon C. Weir, Steven P. Gygi, Samuel C. K. Lee, Ana Vujic, Katherine A Dinan, Jeffrey C. Davis, Christian Shigley
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204595 (2018)
PLoS ONE
PLoS ONE
The in vivo microenvironment of tissues provides myriad unique signals to cells. Thus, following isolation, many cell types change in culture, often preserving some but not all of their in vivo characteristics in culture. At least some of the in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f8a8528f5753c09b5ab65c97cc67d8
Autor:
Jeffrey C. Davis, Douglas A. Melton, José Rivera-Feliciano, Elise N. Engquist, Aharon Helman, Christine M. Langston
Publikováno v:
Current Protocols in Stem Cell Biology
Our laboratory and others have developed protocols to generate glucose‐responsive stem cell–derived β cells in vitro. The cells resulting from these protocols could supplement or replace the use of human cadaveric islets for cell‐based therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b3a50c77618342f716dbfc61ea464e
https://pubmed.ncbi.nlm.nih.gov/31756031
https://pubmed.ncbi.nlm.nih.gov/31756031
Autor:
Quan Pham, Arielle Rothman, Juerg R. Straubhaar, Douglas A. Melton, Jeffrey C. Davis, Aubrey L. Faust, David M. Sabatini, Aharon Helman, Andrew L. Cangelosi
Publikováno v:
PMC
Cell Metab
Cell Metab
A drastic transition at birth, from constant maternal nutrient supply in utero to intermittent postnatal feeding, requires changes in the metabolic system of the neonate. Despite their central role in metabolic homeostasis, little is known about how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05352f46435805eaf2b081025ba373c2
https://doi.org/10.1016/j.cmet.2020.04.004
https://doi.org/10.1016/j.cmet.2020.04.004
Autor:
Douglas A. Melton, Rebecca L. Cardone, Jonathan C. Chen, Jeffrey C. Davis, Tiago C. Alves, David R. Liu, Richard G. Kibbey, Jennifer H. R. Kenty, Aharon Helman
Publikováno v:
Cell reports
SUMMARY Stem cell-derived β (SC-β) cells could provide unlimited human β cells toward a curative diabetes treatment. Differentiation of SC-β cells yields transplantable islets that secrete insulin in response to glucose challenges. Following tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ed308f7155e1cfffa6c5f667ec2290
http://europepmc.org/articles/PMC7433758
http://europepmc.org/articles/PMC7433758
Autor:
G. Wayne Minshall, Jeffrey C. Davis
Publikováno v:
Oecologia. 119(2)
Nitrate and phosphate solutions were released into two reaches of two central Idaho streams to determine within- and between-stream variability in uptake lengths, uptake rates, and mass transfer coefficients. Physical and biotic stream characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e8674c65523481aa729902c101af64
https://pubmed.ncbi.nlm.nih.gov/28307975
https://pubmed.ncbi.nlm.nih.gov/28307975
Autor:
Jeffrey C. Davis, Gay A. Davis
Publikováno v:
Journal of the North American Benthological Society. 30:1117-1128
The effects of barriers to migration by adult salmon smolt have been well studied, but effects to migration of juvenile salmon during freshwater residency have not been evaluated thoroughly. We tested for differences in the relative abundance of juve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0497d6f99ea616f2f924b6ee4a2854ee
https://doi.org/10.1899/10-090.1
https://doi.org/10.1899/10-090.1
Publikováno v:
Biology of Reproduction. 84:886-893
Retinoic acid (RA) is required for germ cell differentiation, the regulation of which gives rise to a constant production of mature sperm. In testes from 3-day postpartum (dpp) RARE-hsplacZ mice, periodic regions positive for beta-galactosidase activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0393cc0a912248bc8baefddf59b5eecb
https://doi.org/10.1095/biolreprod.110.089755
https://doi.org/10.1095/biolreprod.110.089755
Publikováno v:
Aquatic Sciences. 67:424-433
In running water ecosystems, the use of community attributes to infer biological integrity is widespread. In contrast, functional variables like energy flow and elemental cycling have received considerably less attention. In this study, we quantify o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7fc3dece57f1770a6cb3763b062be74
https://doi.org/10.1007/s00027-005-0790-5
https://doi.org/10.1007/s00027-005-0790-5