Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jeffrey C Medley"'
Autor:
Jeffrey C. Medley, Rachel N. Yim, Joseph DiPanni, Brandon Sebou, Blake Shaffou, Evan Cramer, Colin Wu, Megan Kabara, Mi Hye Song
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108410- (2023)
Summary: Spindle bipolarity is critical for genomic integrity. As centrosome number often dictates bipolarity, tight control of centrosome assembly is vital for faithful cell division. The master centrosome regulator ZYG-1/Plk4 plays a pivotal role i
Externí odkaz:
https://doaj.org/article/c28c023cc40f48acbf4cfdd6051f2109
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 12, Pp 3937-3946 (2017)
As the primary microtubule-organizing center, centrosomes play a key role in establishing mitotic bipolar spindles that secure correct transmission of genomic content. For the fidelity of cell division, centrosome number must be strictly controlled b
Externí odkaz:
https://doaj.org/article/a2b7e8ec6bfc447fa479755065f9566c
Publikováno v:
Biology Open, Vol 6, Iss 1, Pp 17-28 (2017)
Centrosomes are the primary microtubule-organizing centers that orchestrate microtubule dynamics during the cell cycle. The correct number of centrosomes is pivotal for establishing bipolar mitotic spindles that ensure accurate segregation of chromos
Externí odkaz:
https://doaj.org/article/bbe7a0ce7f9e45caaf7b970ad99e12fe
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006519 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1006370.].
Externí odkaz:
https://doaj.org/article/0b38ac9da8aa40ae979efbd18aaba334
Publikováno v:
microPublication biology. 2022
By using CRISPR/Cas9 genome-editing, we have generated epitope-tagged KIN-3 and KIN-10 expressing strains at the endogenous C-terminal loci in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d348061d368aab080db70d1dffbe761
https://pubmed.ncbi.nlm.nih.gov/35685274
https://pubmed.ncbi.nlm.nih.gov/35685274
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006370 (2016)
Centrosomes are critical sites for orchestrating microtubule dynamics, and exhibit dynamic changes in size during the cell cycle. As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure pr
Externí odkaz:
https://doaj.org/article/0182d94b5f1748be882b7652d08c07c8
Publikováno v:
Genetics
InCaenorhabditis elegans, germline injection of Cas9 complexes is reliably used to achieve genome editing through homology-directed repair of Cas9-generated DNA breaks. To prevent Cas9 from targeting repaired DNA, additional blocking mutations are of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df66b2ff4fb20b5283d46be2a5af60f
http://europepmc.org/articles/PMC8733430
http://europepmc.org/articles/PMC8733430
Publikováno v:
WIREs RNA. 12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cafee86786fb51bbff09ae1c0ce0b61
https://doi.org/10.1002/wrna.1655
https://doi.org/10.1002/wrna.1655
Publikováno v:
Wiley Interdisciplinary Reviews. RNA
microRNAs (miRNAs) play a central role in the regulation of gene expression by targeting specific mRNAs for degradation or translational repression. Each miRNA is post‐transcriptionally processed into a duplex comprising two strands. One of the two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be3c0273117f12cb977c3da92c1af15e
https://doi.org/10.1002/wrna.1627
https://doi.org/10.1002/wrna.1627
Autor:
Mi Hye Song, Jeffrey C. Medley, Joseph R. DiPanni, Brandon M. Sebou, Luke Schira, Blake M. Shaffou
Aberrant centrosome numbers are associated with human cancers. The levels of centrosome regulators positively correlate with centrosome number. Thus, tight control of centrosome protein levels is critical. In Caenorhabditis elegans, the anaphase-prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b2c7d2a1bd8bca3d61736b1680e1c3
https://doi.org/10.1101/2020.08.12.248658
https://doi.org/10.1101/2020.08.12.248658
