Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Jeffrey C Edberg"'
Autor:
Esther Zumaquero, Sara L Stone, Christopher D Scharer, Scott A Jenks, Anoma Nellore, Betty Mousseau, Antonio Rosal-Vela, Davide Botta, John E Bradley, Wojciech Wojciechowski, Travis Ptacek, Maria I Danila, Jeffrey C Edberg, S Louis Bridges Jr, Robert P Kimberly, W Winn Chatham, Trenton R Schoeb, Alexander F Rosenberg, Jeremy M Boss, Ignacio Sanz, Frances E Lund
Publikováno v:
eLife, Vol 8 (2019)
Although B cells expressing the IFNγR or the IFNγ-inducible transcription factor T-bet promote autoimmunity in Systemic Lupus Erythematosus (SLE)-prone mouse models, the role for IFNγ signaling in human antibody responses is unknown. We show that
Externí odkaz:
https://doaj.org/article/fc145a6e8204428a8ea15655113e477f
Autor:
Angela M. Mickle, Jared J. Tanner, Lisa H. Antoine, Cynthia Garvan, Song Lai, Rene Przkora, Jeffrey C. Edberg, Roland Staud, David Redden, Burel R. Goodin, Catherine C. Price, Roger B. Fillingim, Kimberly T. Sibille
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100794- (2024)
Externí odkaz:
https://doaj.org/article/a4f26d2d3eed4209b4f4e0ac5d966c7f
Autor:
Lindsay L Waite, Benjamin eWeaver, Kenneth eDay, Xinrui eLi, Kevin eRoberts, Andrew W Gibson, Jeffrey C Edberg, Robert P Kimberly, Devin M Absher, Hemant K Tiwari
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
DNA methylation levels vary markedly by cell-type makeup of a sample. Understanding these differences and estimating the cell-type makeup of a sample is an important aspect of studying DNA methylation. DNA from leukocytes in whole blood is simple to
Externí odkaz:
https://doaj.org/article/a85ab6d985794e318ea7de25491bba07
Autor:
Michael I Falola, Howard W Wiener, Nathan E Wineinger, Gary R Cutter, Robert P Kimberly, Jeffrey C Edberg, Donna K Arnett, Richard A Kaslow, Jianming Tang, Sadeep Shrestha
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64813 (2013)
BACKGROUND:Anthrax and its etiologic agent remain a biological threat. Anthrax vaccine is highly effective, but vaccine-induced IgG antibody responses vary widely following required doses of vaccinations. Such variation can be related to genetic fact
Externí odkaz:
https://doaj.org/article/95e2080f77f649eb82eaf0144e61c8a5
Autor:
Bahram Namjou, Xana Kim-Howard, Celi Sun, Adam Adler, Sharon A Chung, Kenneth M Kaufman, Jennifer A Kelly, Stuart B Glenn, Joel M Guthridge, Robert H Scofield, Robert P Kimberly, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Jae-Hoon Kim, Jiyoung Choi, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Susan A Boackle, Barry I Freedman, Betty P Tsao, Carl D Langefeld, Timothy J Vyse, Chaim O Jacob, Bernardo Pons-Estel, Argentine Collaborative Group, Timothy B Niewold, Kathy L Moser Sivils, Joan T Merrill, Juan-Manuel Anaya, Gary S Gilkeson, Patrick M Gaffney, Sang-Cheol Bae, Marta E Alarcón-Riquelme, BIOLUPUS and GENLES Networks, John B Harley, Lindsey A Criswell, Judith A James, Swapan K Nath
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69404 (2013)
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individual
Externí odkaz:
https://doaj.org/article/7f544fb4ff94405a99392c0cc98528bd
Autor:
Julio E Molineros, Amit K Maiti, Celi Sun, Loren L Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A Kelly, Timothy B Niewold, Gary S Gilkeson, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D Reveille, Luis M Vilá, Barry I Freedman, Betty P Tsao, Lindsey A Criswell, Chaim O Jacob, Jason H Moore, Timothy J Vyse, Carl L Langefeld, Joel M Guthridge, Patrick M Gaffney, Kathy L Moser, R Hal Scofield, Marta E Alarcón-Riquelme, BIOLUPUS Network, Scott M Williams, Joan T Merrill, Judith A James, Kenneth M Kaufman, Robert P Kimberly, John B Harley, Swapan K Nath
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003222 (2013)
Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with a strong genetic component. African-Americans (AA) are at increased risk of SLE, but the genetic basis of this risk is largely unknown. To identify causal variants in SLE l
Externí odkaz:
https://doaj.org/article/74744baacd384c39998a0eac8019495c
Autor:
Yun Deng, Jian Zhao, Daisuke Sakurai, Kenneth M Kaufman, Jeffrey C Edberg, Robert P Kimberly, Diane L Kamen, Gary S Gilkeson, Chaim O Jacob, R Hal Scofield, Carl D Langefeld, Jennifer A Kelly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Timothy J Vyse, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Peter K Gregersen, Juan-Manuel Anaya, Timothy B Niewold, Joan T Merrill, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Rita M Cantor, Weiling Chen, Jeniffer M Grossman, Bevra H Hahn, John B Harley, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Elizabeth E Brown, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003336 (2013)
We previously reported that the G allele of rs3853839 at 3'untranslated region (UTR) of Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased risk for systemic lupus erythematosus (SLE) in 9,274 Eastern Asians [
Externí odkaz:
https://doaj.org/article/e01c7a6e68b7433fab433c9fe327b367
Autor:
Daisuke Sakurai, Jian Zhao, Yun Deng, Jennifer A Kelly, Elizabeth E Brown, John B Harley, Sang-Cheol Bae, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Jeffrey C Edberg, Robert P Kimberly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Kenneth M Kaufman, Timothy J Vyse, Chaim O Jacob, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Diane L Kamen, Gary S Gilkeson, Timothy B Niewold, Joan T Merrill, R Hal Scofield, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Jae-Hoon Kim, Jiyoung Choi, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Juan-Manuel Anaya, Javier Martin, C Yung Yu, Deh-Ming Chang, Yeong Wook Song, Carl D Langefeld, Weiling Chen, Jennifer M Grossman, Rita M Cantor, Bevra H Hahn, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003870 (2013)
Immunoregulatory cytokine interleukin-10 (IL-10) is elevated in sera from patients with systemic lupus erythematosus (SLE) correlating with disease activity. The established association of IL10 with SLE and other autoimmune diseases led us to fine ma
Externí odkaz:
https://doaj.org/article/33558ef9795b4c2f9aa7967c0abd4a4d
Autor:
Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao
Publikováno v:
PLoS Genetics, Vol 7, Iss 5, p e1002079 (2011)
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding complement regulator factor H (CFH) and five CFH-related proteins (CFHR1-CFHR5) within the chro
Externí odkaz:
https://doaj.org/article/714680860d754c02ba45e9b2d825dcfd
Autor:
Jianming Wu, Maureen H Richards, Jinhai Huang, Lena Al-Harthi, Xiulong Xu, Rui Lin, Fenglong Xie, Andrew W Gibson, Jeffrey C Edberg, Robert P Kimberly
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26143 (2011)
FasL expression on human immune cells and cancer cells plays important roles in immune homeostasis and in cancer development. Our previous study suggests that polymorphisms in the FasL promoter can significantly affect the gene expression in human ce
Externí odkaz:
https://doaj.org/article/196ad848a552447d811e6c6d9e85f662