Zobrazeno 1 - 10
of 626
pro vyhledávání: '"Jeffrey C, Murray"'
Autor:
Azeez Alade, Peter Mossey, Waheed Awotoye, Tamara Busch, Abimbola M. Oladayo, Emmanuel Aladenika, Mojisola Olujitan, Emma Wentworth, Deepti Anand, Thirona Naicker, Lord J. J. Gowans, Mekonen A. Eshete, Wasiu L. Adeyemo, Erliang Zeng, Eric Van Otterloo, Michael O’Rorke, Adebowale Adeyemo, Jeffrey C. Murray, Justin Cotney, Salil A. Lachke, Paul Romitti, Azeez Butali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Non-syndromic orofacial clefts (NSOFCs) are common birth defects with a complex etiology. While over 60 common risk loci have been identified, they explain only a small proportion of the heritability for NSOFCs. Rare variants have been impli
Externí odkaz:
https://doaj.org/article/95d6a791a7eb4ad7b423f503b9f69c2c
Autor:
Abimbola M. Oladayo, Oluwakemi Odukoya, Veronica Sule, Ikenna Molobe, Tamara Busch, Babatunde Akodu, Wasiu L. Adeyemo, Lord J. J. Gowans, Mekonen Eshete, Azeez Alade, Waheed Awotoye, Adebowale A. Adeyemo, Peter A. Mossey, Anya E. R. Prince, Jeffrey C. Murray, Azeez Butali
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background A fundamental ethical issue in African genomics research is how socio-cultural factors impact perspectives, acceptance, and utility of genomic information, especially in stigmatizing conditions like orofacial clefts (OFCs). Previo
Externí odkaz:
https://doaj.org/article/4751704d52b040749b41c121b63e8a35
Autor:
Abimbola Oladayo, Lord Jephthah Joojo Gowans, Waheed Awotoye, Azeez Alade, Tamara Busch, Thirona Naicker, Mekonen A. Eshete, Wasiu L. Adeyemo, Jacqueline B. Hetmanski, Erliang Zeng, Olawale Adamson, Chinyere Adeleke, Mary Li, Veronica Sule, Sami Kayali, Joy Olotu, Peter A. Mossey, Solomon Obiri‐Yeboah, Carmen J. Buxo, Terri Beaty, Margaret Taub, Peter Donkor, Mary L. Marazita, Oluwakemi Odukoya, Adebowale A. Adeyemo, Jeffrey C. Murray, Anya Prince, Azeez Butali
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract Introduction The frequency and implications of secondary findings (SFs) from genomic testing data have been extensively researched. However, little is known about the frequency or reporting of SFs in Africans, who are underrepresented in lar
Externí odkaz:
https://doaj.org/article/4d477af3634b4221a6b0a0f3e5017d57
Autor:
Kelsey Robinson, Trenell J. Mosley, Kenneth S. Rivera-González, Christopher R. Jabbarpour, Sarah W. Curtis, Wasiu Lanre Adeyemo, Terri H. Beaty, Azeez Butali, Carmen J. Buxó, David J. Cutler, Michael P. Epstein, Lord J.J. Gowans, Jacqueline T. Hecht, Jeffrey C. Murray, Gary M. Shaw, Lina Moreno Uribe, Seth M. Weinberg, Harrison Brand, Mary L. Marazita, Robert J. Lipinski, Elizabeth J. Leslie
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100234- (2023)
Summary: Cleft palate (CP) is one of the most common craniofacial birth defects; however, there are relatively few established genetic risk factors associated with its occurrence despite high heritability. Historically, CP has been studied as a singl
Externí odkaz:
https://doaj.org/article/d701a794d6d64abda81ebac6e8be9898
Autor:
Waheed Awotoye, Peter A. Mossey, Jacqueline B. Hetmanski, Lord J. J. Gowans, Mekonen A. Eshete, Wasiu L. Adeyemo, Azeez Alade, Erliang Zeng, Olawale Adamson, Thirona Naicker, Deepti Anand, Chinyere Adeleke, Tamara Busch, Mary Li, Aline Petrin, Babatunde S. Aregbesola, Ramat O. Braimah, Fadekemi O. Oginni, Ayodeji O. Oladele, Abimbola Oladayo, Sami Kayali, Joy Olotu, Mohaned Hassan, John Pape, Peter Donkor, Fareed K. N. Arthur, Solomon Obiri-Yeboah, Daniel K. Sabbah, Pius Agbenorku, Gyikua Plange-Rhule, Alexander Acheampong Oti, Rose A. Gogal, Terri H. Beaty, Margaret Taub, Mary L. Marazita, Michael J. Schnieders, Salil A. Lachke, Adebowale A. Adeyemo, Jeffrey C. Murray, Azeez Butali
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The majority (85%) of nonsyndromic cleft lip with or without cleft palate (nsCL/P) cases occur sporadically, suggesting a role for de novo mutations (DNMs) in the etiology of nsCL/P. To identify high impact protein-altering DNMs that contrib
Externí odkaz:
https://doaj.org/article/0796813889b94d029ee132863003d559
Autor:
Steven Hawken, PhD, Brieanne Olibris, PhD, Robin Ducharme, MSc, A. Brianne Bota, PhD, Jeffrey C. Murray, MD, Beth K. Potter, PhD, Mark Walker, MD, Pranesh Chakraborty, MD, Kumanan Wilson, MD
Publikováno v:
AJOG Global Reports, Vol 2, Iss 4, Pp 100091- (2022)
BACKGROUND: Accurate estimates of gestational age in pregnancy are important for the provision of optimal care. Although current guidelines generally recommend estimating gestational age via first-trimester ultrasound measurement of crown–rump leng
Externí odkaz:
https://doaj.org/article/1139a72b35594c9ebc01f69b7deb32d0
Autor:
Johanna M. Huusko, Heli Tiensuu, Antti M. Haapalainen, Anu Pasanen, Pinja Tissarinen, Minna K. Karjalainen, Ge Zhang, Kaare Christensen, Kelli K. Ryckman, Bo Jacobsson, Jeffrey C. Murray, Stephen F. Kingsmore, Mikko Hallman, Louis J. Muglia, Mika Rämet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB). Intracellular heat shock proteins act as m
Externí odkaz:
https://doaj.org/article/f305df8cd6b34e51b15c496289d931fa
Autor:
Rasha N. Alotaibi, Brian J. Howe, Lina M. Moreno Uribe, Consuelo Valencia Ramirez, Claudia Restrepo, Frederic W. B. Deleyiannis, Carmencita Padilla, Ieda M. Orioli, Carmen J. Buxó, Jacqueline T. Hecht, George L. Wehby, Katherine Neiswanger, Jeffrey C. Murray, John R. Shaffer, Seth M. Weinberg, Mary L. Marazita
Publikováno v:
Frontiers in Dental Medicine, Vol 2 (2022)
Odontogenesis is a complex process, where disruption can result in dental anomalies and/or increase the risk of developing dental caries. Based on previous studies, certain dental anomalies tend to co-occur in patients, suggesting that these traits m
Externí odkaz:
https://doaj.org/article/c38559fa829e4202a54842f1ed2b3eec
Autor:
Xueping Liu, Dorte Helenius, Line Skotte, Robin N. Beaumont, Matthias Wielscher, Frank Geller, Julius Juodakis, Anubha Mahajan, Jonathan P. Bradfield, Frederick T. J. Lin, Suzanne Vogelezang, Mariona Bustamante, Tarunveer S. Ahluwalia, Niina Pitkänen, Carol A. Wang, Jonas Bacelis, Maria C. Borges, Ge Zhang, Bruce A. Bedell, Robert M. Rossi, Kristin Skogstrand, Shouneng Peng, Wesley K. Thompson, Vivek Appadurai, Debbie A. Lawlor, Ilkka Kalliala, Christine Power, Mark I. McCarthy, Heather A. Boyd, Mary L. Marazita, Hakon Hakonarson, M. Geoffrey Hayes, Denise M. Scholtens, Fernando Rivadeneira, Vincent W. V. Jaddoe, Rebecca K. Vinding, Hans Bisgaard, Bridget A. Knight, Katja Pahkala, Olli Raitakari, Øyvind Helgeland, Stefan Johansson, Pål R. Njølstad, João Fadista, Andrew J. Schork, Ron Nudel, Daniel E. Miller, Xiaoting Chen, Matthew T. Weirauch, Preben Bo Mortensen, Anders D. Børglum, Merete Nordentoft, Ole Mors, Ke Hao, Kelli K. Ryckman, David M. Hougaard, Leah C. Kottyan, Craig E. Pennell, Leo-Pekka Lyytikainen, Klaus Bønnelykke, Martine Vrijheid, Janine F. Felix, William L. Lowe, Struan F. A. Grant, Elina Hyppönen, Bo Jacobsson, Marjo-Riitta Jarvelin, Louis J. Muglia, Jeffrey C. Murray, Rachel M. Freathy, Thomas M. Werge, Mads Melbye, Alfonso Buil, Bjarke Feenstra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Gestational duration depends on both maternal and fetal genetic influences. Here, the authors perform a fetal genome-wide association meta-analysis and find that a locus on 2q13 is associated with pregnancy duration and further show that the lead SNP
Externí odkaz:
https://doaj.org/article/0663e700e52e44dd96778ff7a9670192
Autor:
Anisur Rahman, Fyezah Jehan, Ana Alfirevic, Kenneth Maleta, Ulla Ashorn, Per Ashorn, Kelli K Ryckman, Tahmeed Ahmed, Usha Dhingra, Arup Dutta, Saikat Deb, Sunil Sazawal, Rajiv Bahl, Salahuddin Ahmed, Stephen H Kennedy, Monjur Rahman, Jesmin Pervin, Cathrine Hoyo, Rasheda Khanam, Sayedur Rahman, James A Litch, Aneeta Hotwani, Daniel E Roth, Ge Zhang, Abdullah Al Mahmud, Mikko Hallman, Huan Xu, Usma Mehmood, Zarko Alfirevic, Jeffrey C Murray, Bellington Vwalika, Susan Murphy, Patrick Musonda, Nagendra Monangi, Angharad Care, Fahad Aftab, Waqasuddin Khan, Joan T Price, Yuemei Fan, Thanh Q Le, Julio A Landero, Gerald F Combs, Elizabeth Belling, Joanne Chappell, Fansheng Kong, Criag Lacher, Nabidul Haque Chowdhury, Furqan Kabir, Imran Nisar, Ambreen Nizar, Javairia Khalid, Said Ali, Mohammed Hamad Juma, Md Munirul Islam, Laura Goodfellow, Juhi K Gupta, Larry Rand, Courtney Baruch-Gravett, Abdullah Baqui, Jane Hirst, Laura L Jelliffe-Pawlowski, Jeffrey Stringer, Louis Muglia
Publikováno v:
BMJ Global Health, Vol 6, Iss 9 (2021)
Background Selenium (Se), an essential trace mineral, has been implicated in preterm birth (PTB). We aimed to determine the association of maternal Se concentrations during pregnancy with PTB risk and gestational duration in a large number of samples
Externí odkaz:
https://doaj.org/article/1f235ae3017d4e429794289a5fb9ed16