Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jeffrey Browning"'
Autor:
MINHDA LE, ELAINE (YILING) WU, JARETT BERRY, JEFFREY BROWNING, JAMES DELEMOS, IAN NEELAND, ILDIKO LINGVAY
Publikováno v:
Diabetes. 71
Proton magnetic resonance spectroscopy (MRS) provides an accurate quantification of liver fat, but the threshold of 5.5% for “normal” is challenged. We evaluated the relationship between liver fat content and metabolic parameters to explore what
Autor:
STANISLAW DEJA, JUSTIN A. FLETCHER, BLANKA KUCEJOVA, MONIKA N. MIZERSKA, XIAORONG FU, CHAI-WAN KIM, JEFFREY BROWNING, JAMEY YOUNG, JAY D. HORTON, SHAWN C. BURGESS
Publikováno v:
Diabetes. 71
Activation of fatty acid oxidation is a promising therapy for NAFLD. Lowering acetyl-CoA carboxylase (ACC) activity depletes malonyl-CoA, activates CPT1, and increases mitochondrial fatty acid delivery. ACC1/2 liver double KO mice (LDKO) are protecte
Publikováno v:
Endocrine Practice. 28:S61-S62
Autor:
Srishti Saha, Kershaw Patel, Marat Fudim, Colby Ayers, Lisa B. VanWagner, Vishal N. Rao, Mark H. Drazner, Sonia Garg, Amit G. Singal, Jeffrey Browning, Ian J. Neeland, Ambarish Pandey
Publikováno v:
Gastroenterology. 162:S-1201
Autor:
Jeffrey Browning
Publikováno v:
Scopus-Elsevier
Autor:
Jeffrey Browning, Wenie S. Din, Raymond G. Goodwin, Craig A. Smith, Barbara Ehrenfels, Todd L. VanArsdale, Barbara N. Walter, Paul D. Crowe, Carl F. Ware, Catherine Hession
Publikováno v:
Science. 264:707-710
Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. The cell surface form of LT-alpha is assembled during
Publikováno v:
Scopus-Elsevier
A human T cell hybridoma, II-23.D7, was induced with phorbol ester to express a surface form of lymphotoxin (LT, TNF-beta) and an associated 33-kDa glycoprotein. The LT epitopes were detected by surface immunofluorescence staining and by immunoprecip
Publikováno v:
Scopus-Elsevier
Phospholipase A2 (PLA2) enzymes hydrolyze membrane phospholipids liberating fatty acid and lysophospholipid. This event is thought to be the rate-limiting step in the generation of the lipid proinflammatory mediators, the eicosanoids and possibly pla
Autor:
Jeffrey Browning, Ribolini, A.
Publikováno v:
Scopus-Elsevier
The relative ability of TNF and lymphotoxin (LT) to inhibit the growth of five human tumor cell lines was examined both in the presence and absence of IFN-gamma. Two adenocarcinoma lines, HT-29 and SK-CO-1, were 20- and 320-fold more sensitive to the