Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jeffrey B.S. Gaither"'
Publikováno v:
PLOS Computational Biology. 18:e1010560
Although the role of evolutionary process in cancer progression is widely accepted, increasing attention is being given to the evolutionary mechanisms that can lead to differences in clinical outcome. Recent studies suggest that the temporal order in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c0fe984c8fb0da5a035993cb317125
https://doi.org/10.1371/journal.pcbi.1010560
https://doi.org/10.1371/journal.pcbi.1010560
Autor:
James L. Li, Peter White, Grant E. Lammi, Harkness Kuck, James Fitch, Jeffrey B.S. Gaither, David M Gordon, Benjamin J. Kelly
Publikováno v:
GigaScience
Background The role of synonymous single-nucleotide variants in human health and disease is poorly understood, yet evidence suggests that this class of “silent” genetic variation plays multiple regulatory roles in both transcription and translati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b64a104fec37d07e0a017365f47216
https://doi.org/10.1093/gigascience/giab023
https://doi.org/10.1093/gigascience/giab023
Autor:
Grant E. Lammi, James Fitch, James L. Li, David M Gordon, Benjamin J. Kelly, Jeffrey B.S. Gaither, Peter White, Harkness Kuck
BackgroundIn most organisms the structure of an mRNA molecule is crucial in determining speed of translation, half-life, splicing propensities and final protein configuration. Synonymous variants which distort this wildtype mRNA structure may be path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1203108fe79140146d38563815873238
