Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Jeffrey B. Arterburn"'
Autor:
Stacey L. P. Scroggs, Christy C. Andrade, Ramesh Chinnasamy, Sasha R. Azar, Erin E. Schirtzinger, Erin I. Garcia, Jeffrey B. Arterburn, Kathryn A. Hanley, Shannan L. Rossi
Publikováno v:
Viruses, Vol 12, Iss 9, p 1022 (2020)
Repurposing FDA-approved compounds could provide the fastest route to alleviate the burden of disease caused by flaviviruses. In this study, three fluoroquinolones, enoxacin, difloxacin and ciprofloxacin, curtailed replication of flaviviruses Zika (Z
Externí odkaz:
https://doaj.org/article/1ab7b3d2e4044ce293442d9277281551
Autor:
Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz
Publikováno v:
Obstetrics and Gynecology International, Vol 2013 (2013)
Endometrial carcinoma is the most common cancer of the female reproductive tract. GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has been identified as the third estrogen receptor, in addition to ERα and ERβ. High GPER exp
Externí odkaz:
https://doaj.org/article/26a5f4cdf567496783c98a9ef452ad7c
Publikováno v:
Annual Review of Pharmacology and Toxicology. 63:295-320
The actions of estrogens and related estrogenic molecules are complex and multifaceted in both sexes. A wide array of natural, synthetic, and therapeutic molecules target pathways that produce and respond to estrogens. Multiple receptors promulgate t
Autor:
Eric R. Prossnitz, Jeffrey B. Arterburn, Jeffrey P. Norenberg, Helen J. Hathaway, Chinnasamy Ramesh, Tapan K. Nayak
Figure S1: HPLC radiochromatograms of labeled compounds 5,6 and 8. Figure S2. HPLC radiochromatograms of urine and plasma from mouse injected with labeled compound 5. Table S1. Time-dependent biodistribution of labeled compound 5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d53710af8e448658953e1a06bf54fdf
https://doi.org/10.1158/1541-7786.22510960
https://doi.org/10.1158/1541-7786.22510960
Autor:
V. Craig Jordan, Nae J. Dun, Eric R. Prossnitz, Tudor I. Oprea, Jeffrey B. Arterburn, Anne L. Donato, Michael A. Black, Heather E. Cunliffe, Michael J. Slifker, Heather A. Shupp, Smitha Yerrum, Eugen Brailoiu, Eric A. Ariazi
Supplementary Figure 1 from The G Protein–Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor–Positive Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ffbce276b8352f022b19cd9b0322dd
https://doi.org/10.1158/0008-5472.22387254.v1
https://doi.org/10.1158/0008-5472.22387254.v1
Autor:
V. Craig Jordan, Nae J. Dun, Eric R. Prossnitz, Tudor I. Oprea, Jeffrey B. Arterburn, Anne L. Donato, Michael A. Black, Heather E. Cunliffe, Michael J. Slifker, Heather A. Shupp, Smitha Yerrum, Eugen Brailoiu, Eric A. Ariazi
Supplementary Methods from The G Protein–Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor–Positive Breast Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a8f40cf723971791e40813a381ee4f
https://doi.org/10.1158/0008-5472.22387251
https://doi.org/10.1158/0008-5472.22387251
Autor:
Jeffrey B. Arterburn, Rishi R. Sapkota, Tanner Schaub, Marat R. Talipov, Jacqueline M. Jarvis
Publikováno v:
ChemistryOpen
Exquisite control of catalytic metathesis reactivity is possible through ligand‐based variation of ruthenium carbene complexes. Sterically hindered alkenes, however, remain a generally recalcitrant class of substrates for intermolecular cross‐met
Autor:
Shannan L. Rossi, Steven G. Widen, Kathryn A. Hanley, Jeffrey B. Arterburn, Ramesh Chinnasamy, Stacey L P Scroggs, Nikos Vasilakis, Sasha R. Azar, Jordan T. Gass
Drugs against flaviviruses such as dengue (DENV) and Zika (ZIKV) virus are urgently needed. We previously demonstrated that three fluoroquinolones, ciprofloxacin, enoxacin, and difloxacin, suppress replication of six flaviviruses. To investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc3959a8b22e8c2089d27ab87665464
Autor:
Meilian Liu, Wadih Arap, Geetanjali Sharma, Jonathan L. Brigman, Chelin Hu, Franck Mauvais-Jarvis, Daniela I. Staquicini, Helen J. Hathaway, Renata Pasqualini, Eric R. Prossnitz, Jeffrey B. Arterburn
Publikováno v:
Science Translational Medicine. 12
Human obesity has become a global health epidemic, with few safe and effective pharmacological therapies currently available. The systemic loss of ovarian estradiol (E2) in women after menopause greatly increases the risk of obesity and metabolic dys
Autor:
Ramesh Chinnasamy, Ruth G. Perez, Jeffrey B. Arterburn, Ismael Segura-Ulate, Javier Vargas-Medrano, Barbara Yang
Publikováno v:
Neuropharmacology
Multiple system atrophy (MSA) is a fatal demyelinating disorder lacking any disease-modifying therapies. MSA pathology stems from aggregated α-synuclein (aSyn) accumulation in glial cytosolic inclusions of oligodendroglial cell (OLGs), the myelinati