Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Jeffrey B Bonanno"'
Autor:
Sarah C Garrett-Thomson, Aldo Massimi, Elena V Fedorov, Jeffrey B Bonanno, Lisa Scandiuzzi, Brandan Hillerich, Ronald D Seidel, James D Love, Scott J Garforth, Chandan Guha, Steven C Almo
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233578 (2020)
The B7 family represents one of the best-studied subgroups within the Ig superfamily, yet new interactions continue to be discovered. However, this binding promiscuity represents a major challenge for defining the biological contribution of each spec
Externí odkaz:
https://doaj.org/article/27e3018279ae454bb113285e87c0fa4f
Autor:
Stephen Antonysamy, Bradley Condon, Zhanna Druzina, Jeffrey B Bonanno, Tarun Gheyi, Feiyu Zhang, Iain MacEwan, Aiping Zhang, Sheela Ashok, Logan Rodgers, Marijane Russell, John Gately Luz
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84147 (2013)
The enhancer-of-zeste homolog 2 (EZH2) gene product is an 87 kDa polycomb group (PcG) protein containing a C-terminal methyltransferase SET domain. EZH2, along with binding partners, i.e., EED and SUZ12, upon which it is dependent for activity forms
Externí odkaz:
https://doaj.org/article/d0efb2c872af40ed96f0cf32d3038efa
Autor:
Meng-Chiao Ho, Carola Wilczek, Jeffrey B Bonanno, Li Xing, Janina Seznec, Tsutomu Matsui, Lester G Carter, Takashi Onikubo, P Rajesh Kumar, Man K Chan, Michael Brenowitz, R Holland Cheng, Ulf Reimer, Steven C Almo, David Shechter
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57008 (2013)
The arginine methyltransferase PRMT5-MEP50 is required for embryogenesis and is misregulated in many cancers. PRMT5 targets a wide variety of substrates, including histone proteins involved in specifying an epigenetic code. However, the mechanism by
Externí odkaz:
https://doaj.org/article/878e45ee8b9d443eb0cdebf4a4cb2dd7
Autor:
Natalia Cheshenko, Jeffrey B. Bonanno, Hans-Heinrich Hoffmann, Rohit K. Jangra, Kartik Chandran, Charles M. Rice, Steven C. Almo, Betsy C. Herold
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4d1acc8e80fd4e28a655751b6003208d
Publikováno v:
Acta Crystallogr F Struct Biol Commun
Chromatin is the complex assembly of nucleic acids and proteins that makes up the physiological form of the eukaryotic genome. The nucleosome is the fundamental repeating unit of chromatin, and is composed of ∼147 bp of DNA wrapped around a histone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5901e4651f9fdea26c09c6edea1b2
https://doi.org/10.1107/s2053230x20004604
https://doi.org/10.1107/s2053230x20004604
Autor:
Steven C. Almo, Benjamin M. Lorton, David Shechter, Rajesh K. Harijan, Emmanuel S. Burgos, Jeffrey B. Bonanno
Publikováno v:
Biochemistry
Histone H3 arginine 2 (H3R2) is post-translationally modified in three different states by “writers” of the protein arginine methyltransferase (PRMT) family. H3R2 methylarginine isoforms include PRMT5-catalyzed mono- and symmetric di-methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f589e6720f19538dff7bdc65c1f8d6
https://doi.org/10.1021/acs.biochem.0c00035
https://doi.org/10.1021/acs.biochem.0c00035
Autor:
Natalia Cheshenko, Jeffrey B. Bonanno, Hans-Heinrich Hoffmann, Rohit K. Jangra, Kartik Chandran, Charles M. Rice, Steven C. Almo, Betsy C. Herold
Publikováno v:
Communications biology. 5(1)
Herpes simplex virus (HSV) receptor engagement activates phospholipid scramblase triggering Akt translocation to the outer leaflet of the plasma membrane where its subsequent phosphorylation promotes viral entry. We hypothesize that this previously u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5852cf3e5850e77ad9f97acad5298c8
https://pubmed.ncbi.nlm.nih.gov/36245045
https://pubmed.ncbi.nlm.nih.gov/36245045
Autor:
Udupi A. Ramagopal, Mitchell Kronenberg, Scott J. Garforth, Ting-Fang Chou, Kiyokazu Kakugawa, Kenneth Kim, Steven C. Almo, Elena V. Fedorov, Hilde Cheroutre, Sarah C. Garrett-Thomson, Goo-Young Seo, Jeffrey B. Bonanno, Qingyang Wang, Weifeng Liu
Publikováno v:
The Journal of Experimental Medicine
HVEM is a TNF family receptor that binds a TNF protein and Ig family proteins. Using structural biology and mutagenesis, we identified HVEM muteins with selective ligand binding. We verified their function in vivo in models of inflammation and infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbbac404839b01f564d1668a1b27f958
https://doi.org/10.1084/jem.20211112
https://doi.org/10.1084/jem.20211112
Autor:
Kiyokazu Kakugawa, Weifeng Liu, Elena V. Fedorov, Hilde Cheroutre, Goo-Young Seo, Jeffrey B. Bonanno, Ting-Fang Chou, Sarah C. Garrett-Thomson, Steven C. Almo, Udupi A. Ramagopa, Mitchell Kronenberg
HVEM is a TNF (tumor necrosis factor) receptor contributing to a broad range of immune functions involving diverse cell types. It interacts with a TNF ligand, LIGHT, and immunoglobulin (Ig) superfamily members BTLA and CD160. Assessing the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dea66bf858bcc04c09fdb3c6f999ee5
https://doi.org/10.1101/2021.06.16.448617
https://doi.org/10.1101/2021.06.16.448617
Autor:
Ting-Fang Chou, Weifeng Liu, Sarah C. Garrett-Thomson, Goo-Young Seo, Elena Fedorov, Udupi A. Ramagopal, Jeffrey B. Bonanno, Qingyang Wang, Kenneth Kim, Scott J. Garforth, Kiyokazu Kakugawa, Hilde Cheroutre, Mitchell Kronenberg, Steven C. Almo
Publikováno v:
The Journal of Immunology. 208:52.17-52.17
HVEM is a TNF (tumor necrosis factor) receptor contributing to a broad range of immune functions involving diverse cell types. It interacts with a TNF ligand, LIGHT, and immunoglobulin (Ig) superfamily members BTLA and CD160. Assessing the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6da77054e7bdf6da3cfae7baad377c8
https://doi.org/10.4049/jimmunol.208.supp.52.17
https://doi.org/10.4049/jimmunol.208.supp.52.17