Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Jeffrey B, Hodgin"'
Autor:
Samuel P. Border, John E. Tomaszewski, Teruhiko Yoshida, Jeffrey B. Kopp, Jeffrey B. Hodgin, William L. Clapp, Avi Z. Rosenberg, Jill P. Buyon, Pinaki Sarder
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract HistoLens is an open-source graphical user interface developed using MATLAB AppDesigner for visual and quantitative analysis of histological datasets. HistoLens enables users to interrogate sets of digitally annotated whole slide images to e
Externí odkaz:
https://doaj.org/article/d3b33c7071f24ca3a34b44527b736dd1
Autor:
Debora L. Gisch, Michelle Brennan, Blue B. Lake, Jeannine Basta, Mark S. Keller, Ricardo Melo Ferreira, Shreeram Akilesh, Reetika Ghag, Charles Lu, Ying-Hua Cheng, Kimberly S. Collins, Samir V. Parikh, Brad H. Rovin, Lynn Robbins, Lisa Stout, Kimberly Y. Conklin, Dinh Diep, Bo Zhang, Amanda Knoten, Daria Barwinska, Mahla Asghari, Angela R. Sabo, Michael J. Ferkowicz, Timothy A. Sutton, Katherine J. Kelly, Ian H. De Boer, Sylvia E. Rosas, Krzysztof Kiryluk, Jeffrey B. Hodgin, Fadhl Alakwaa, Seth Winfree, Nichole Jefferson, Aydın Türkmen, Joseph P. Gaut, Nils Gehlenborg, Carrie L. Phillips, Tarek M. El-Achkar, Pierre C. Dagher, Takashi Hato, Kun Zhang, Jonathan Himmelfarb, Matthias Kretzler, Shamim Mollah, the Kidney Precision Medicine Project (KPMP), Sanjay Jain, Michael Rauchman, Michael T. Eadon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract There is a need to define regions of gene activation or repression that control human kidney cells in states of health, injury, and repair to understand the molecular pathogenesis of kidney disease and design therapeutic strategies. Comprehe
Externí odkaz:
https://doaj.org/article/8d81e0f3c4d54dd6b9a6681fc0df894c
Autor:
Joonsang Lee, Elisa Warner, Salma Shaikhouni, Markus Bitzer, Matthias Kretzler, Debbie Gipson, Subramaniam Pennathur, Keith Bellovich, Zeenat Bhat, Crystal Gadegbeku, Susan Massengill, Kalyani Perumal, Jharna Saha, Yingbao Yang, Jinghui Luo, Xin Zhang, Laura Mariani, Jeffrey B. Hodgin, Arvind Rao
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Machine learning applied to digital pathology has been increasingly used to assess kidney function and diagnose the underlying cause of chronic kidney disease (CKD). We developed a novel computational framework, clustering-based spatial anal
Externí odkaz:
https://doaj.org/article/0eec12b4c60846b9b414230ba0f4f3e6
Autor:
Kumar Sharma, Guanshi Zhang, Jens Hansen, Petter Bjornstad, Hak Joo Lee, Rajasree Menon, Leila Hejazi, Jian-Jun Liu, Anthony Franzone, Helen C. Looker, Byeong Yeob Choi, Roman Fernandez, Manjeri A. Venkatachalam, Luxcia Kugathasan, Vikas S. Sridhar, Loki Natarajan, Jing Zhang, Varun S. Sharma, Brian Kwan, Sushrut S. Waikar, Jonathan Himmelfarb, Katherine R. Tuttle, Bryan Kestenbaum, Tobias Fuhrer, Harold I. Feldman, Ian H. de Boer, Fabio C. Tucci, John Sedor, Hiddo Lambers Heerspink, Jennifer Schaub, Edgar A. Otto, Jeffrey B. Hodgin, Matthias Kretzler, Christopher R. Anderton, Theodore Alexandrov, David Cherney, Su Chi Lim, Robert G. Nelson, Jonathan Gelfond, Ravi Iyengar, for the Kidney Precision Medicine Project
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
Diabetic kidney disease (DKD) can lead to end-stage kidney disease (ESKD) and mortality; however, few mechanistic biomarkers are available for high-risk patients, especially those without macroalbuminuria. Urine from participants with diabetes from t
Externí odkaz:
https://doaj.org/article/15a3cc7202a34114a72f51162fa19310
Autor:
Joonsang Lee, Elisa Warner, Salma Shaikhouni, Markus Bitzer, Matthias Kretzler, Debbie Gipson, Subramaniam Pennathur, Keith Bellovich, Zeenat Bhat, Crystal Gadegbeku, Susan Massengill, Kalyani Perumal, Jharna Saha, Yingbao Yang, Jinghui Luo, Xin Zhang, Laura Mariani, Jeffrey B. Hodgin, Arvind Rao, the C-PROBE Study
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Pathologists use visual classification to assess patient kidney biopsy samples when diagnosing the underlying cause of kidney disease. However, the assessment is qualitative, or semi-quantitative at best, and reproducibility is challenging.
Externí odkaz:
https://doaj.org/article/fe2e0a13ca2544f7bdcbdd8b50cb682f
Autor:
Jennifer A. Schaub, Fadhl M. AlAkwaa, Phillip J. McCown, Abhijit S. Naik, Viji Nair, Sean Eddy, Rajasree Menon, Edgar A. Otto, Dawit Demeke, John Hartman, Damian Fermin, Christopher L. O’Connor, Lalita Subramanian, Markus Bitzer, Roger Harned, Patricia Ladd, Laura Pyle, Subramaniam Pennathur, Ken Inoki, Jeffrey B. Hodgin, Frank C. Brosius III, Robert G. Nelson, Matthias Kretzler, Petter Bjornstad
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
The molecular mechanisms of sodium-glucose cotransporter-2 (SGLT2) inhibitors (SGLT2i) remain incompletely understood. Single-cell RNA sequencing and morphometric data were collected from research kidney biopsies donated by young persons with type 2
Externí odkaz:
https://doaj.org/article/786e05c40b544ed683f2bef88a499a82
Autor:
Garrett S. Dunlap, Allison C. Billi, Xianying Xing, Feiyang Ma, Mitra P. Maz, Lam C. Tsoi, Rachael Wasikowski, Jeffrey B. Hodgin, Johann E. Gudjonsson, J. Michelle Kahlenberg, Deepak A. Rao
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
Cutaneous lupus is commonly present in patients with systemic lupus erythematosus (SLE). T cells have been strongly suspected to contribute to the pathology of cutaneous lupus; however, our understanding of the relevant T cell phenotypes and function
Externí odkaz:
https://doaj.org/article/aa9befc0293c47f9a47cc27bbdbf3050
Autor:
Piming Zhao, Gizachew B. Tassew, Joanna Y. Lee, Babak Oskouian, Denise P. Muñoz, Jeffrey B. Hodgin, Gordon L. Watson, Felicia Tang, Jen-Yeu Wang, Jinghui Luo, Yingbao Yang, Sarah King, Ronald M. Krauss, Nancy Keller, Julie D. Saba
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Sphingosine-1-phosphate lyase insufficiency syndrome (SPLIS) is a rare metabolic disorder caused by inactivating mutations in sphingosine-1-phosphate lyase 1 (SGPL1), which is required for the final step of sphingolipid metabolism. SPLIS features inc
Externí odkaz:
https://doaj.org/article/9c9d0a0bbea44c69ba3c08fe8f691e88
Autor:
Yijiang Chen, Jarcy Zee, Andrew R. Janowczyk, Jeremy Rubin, Paula Toro, Kyle J. Lafata, Laura H. Mariani, Lawrence B. Holzman, Jeffrey B. Hodgin, Anant Madabhushi, Laura Barisoni
Publikováno v:
Kidney360. 4:648-658
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76f43dd3cb479ad4746afb7d36eecca7
https://doi.org/10.34067/kid.0000000000000116
https://doi.org/10.34067/kid.0000000000000116
Controlled Humidity Levels for Fine Spatial Detail Information in Enzyme-Assisted N-Glycan MALDI MSI
Autor:
Dušan Veličković, Kumar Sharma, Theodore Alexandrov, Jeffrey B. Hodgin, Christopher R. Anderton
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1577-1580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::263c9e921c095ee6725578e3e22f5dfe
https://doi.org/10.1021/jasms.2c00120
https://doi.org/10.1021/jasms.2c00120