Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jeffrey Au"'
Autor:
Charles West, Connor Tobo, Jeffrey Au, David Johnson, M. Abdul Mottaleb, Jessica Robinson, Saloni Shringarpure, David W Griggs, Koyal Garg
Publikováno v:
American Journal of Physiology-Cell Physiology.
Volumetric muscle loss (VML) causes irrecoverable loss of muscle mass and strength and results in permanent disability. VML injury shows extensive fibrosis, which impedes functional tissue regeneration. Our lab has created a biosponge scaffold compos
Publikováno v:
Journal of Orthopaedic Research.
Autor:
Natalia Ziemkiewicz, Josh Madsen, Peter Genovese, David Y. Johnson, Jeffrey Au, Andrew Lin, Allison Paoli, Andrew J. Dunn, Nicholas Pullen, Koyal Garg, Hannah Chauvin, Gabriel Haas
Publikováno v:
J Biomed Mater Res A
Skeletal muscle is inept in regenerating after traumatic injuries such as volumetric muscle loss (VML) due to significant loss of various cellular and acellular components. Currently, there are no approved therapies for the treatment of muscle tissue
Autor:
Hanna Vihma, Kelin Li, Anna Welton-Arndt, Audrey L. Smith, Kiran R. Bettadapur, Rachel B. Gilmore, Eric Gao, Justin L. Cotney, Hsueh-Cheng Huang, Jon L. Collins, Stormy J. Chamberlain, Hyeong-Min Lee, Jeffrey Aubé, Benjamin D. Philpot
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Deletion of the maternal UBE3A allele causes Angelman syndrome (AS); because paternal UBE3A is epigenetically silenced by a long non-coding antisense (UBE3A-ATS) in neurons, this nearly eliminates UBE3A protein in the brain. Reactivating pat
Externí odkaz:
https://doaj.org/article/72e7df6e4aea4466a15644b3c09e8c85
Autor:
Peter Genovese, Andrew J. Dunn, Genevieve Hilliard, Koyal Garg, Jeffrey Au, Josh Madsen, Hannah Chauvin, Allison Paoli, Gabriel Haas, Charles West, Natalia Ziemkiewicz
Publikováno v:
Tissue engineering. Part A. 28(7-8)
Volumetric muscle loss (VML) is the surgical or traumatic loss of skeletal muscle which can cause loss of limb function or permanent disability. VML injuries overwhelms the endogenous regenerative capacity of skeletal muscle and results in poor funct
Autor:
Sara McBride Gagyi, Andrew J. Dunn, Jeffrey Au, Joshua Madsen, Koyal Garg, Hannah Chauvin, Charles West, David Y. Johnson, Natalia Ziemkiewicz, Gabriel Haas
Publikováno v:
J Orthop Res
There is a dearth of therapies that are safe and effective for the treatment of volumetric muscle loss (VML), defined as the surgical or traumatic loss of muscle tissue, resulting in functional impairment. To address this gap in orthopedic care, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfaf91734d02c2bd6693e1e115d5add
https://europepmc.org/articles/PMC8776909/
https://europepmc.org/articles/PMC8776909/
Autor:
Koyal Garg, Jeffrey Au, Gabriel Haas, Andrew J. Dunn, Hannah Chauvin, Peter Genovese, Andrew Lin, Josh Madsen, Allison Paoli
Skeletal muscle is inept in regenerating after traumatic injuries such as volumetric muscle loss (VML) due to significant loss of basal lamina and the resident satellite cells. Currently, there are no approved therapies for the treatment of muscle ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17b1d400c85933f2ea1a6980dea07ba9
https://doi.org/10.1101/2020.05.20.106823
https://doi.org/10.1101/2020.05.20.106823
Autor:
Lanjing Wei, Qi Zhang, Cuncong Zhong, Lily He, Yuxia Zhang, Ahlam M. Armaly, Jeffrey Aubé, Danny R. Welch, Liang Xu, Xiaoqing Wu
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 1962-1980 (2023)
Chemotherapy remains the standard treatment for triple‐negative breast cancer (TNBC); however, chemoresistance compromises its efficacy. The RNA‐binding protein Hu antigen R (HuR) could be a potential therapeutic target to enhance the chemotherap
Externí odkaz:
https://doaj.org/article/7a76c1ec594e40d5afc47174dc9034a1
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Upregulation of an RNA-binding protein HuR has been implicated in glomerular diseases. Herein, we evaluated whether it is involved in renal tubular fibrosis. Methods HuR was firstly examined in human kidney biopsy tissue with tubu
Externí odkaz:
https://doaj.org/article/b0056bfe39d1442a8fc59a8fbf6be5ef
Autor:
Owen Jensen, Shubhanshi Trivedi, Jackson G. Cacioppo, Kelin Li, Jeffrey Aubé, J. Scott Hale, Edward T. Ryan, Daniel T Leung
Publikováno v:
Pathogens and Immunity, Vol 7, Iss 1 (2022)
ERRATUM TO: USE OF A MAIT ACTIVATING LIGAND, 5-OP-RU, AS A MUCOSAL ADJUVANT IN A MURINE MODEL OF VIBRIO CHOLERAE O1 VACCINATION DOI: 10.20411/pai.v7i1.525 Reason: The authors sincerely regret the inadvertent omission of Jackson G. Cacioppo as coa
Externí odkaz:
https://doaj.org/article/79c872b19acf48c5a94db0ea1e825104