Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Jeffrey A. Sorelle"'
Autor:
Mitchell S. von Itzstein, MD, Jialiang Liu, PhD, Hong Mu-Mosley, PhD, Farjana Fattah, PhD, Jason Y. Park, MD, PhD, Jeffrey A. SoRelle, MD, J. David Farrar, PhD, Mary E. Gwin, MD, David Hsiehchen, MD, Yvonne Gloria-McCutchen, Edward K. Wakeland, PhD, Suzanne Cole, MD, Sheena Bhalla, MD, Radhika Kainthla, MD, Igor Puzanov, MD, MSCI, Benjamin Switzer, DO, MHSA, MS, Gregory A. Daniels, MD, PhD, Yousef Zakharia, MD, Montaser Shaheen, MD, Jianjun Zhang, MD, PhD, Yang Xie, PhD, David E. Gerber, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 6, Iss 1, Pp 100751- (2025)
Introduction: Racial and ethnic disparities in the presentation and outcomes of lung cancer are widely known. To evaluate potential factors contributing to these observations, we measured systemic immune parameters in Black and White patients with lu
Externí odkaz:
https://doaj.org/article/e166f0b2862d482b95a71942e6dcb113
Autor:
Xue Zhong, Nagesh Peddada, Jianhui Wang, James J. Moresco, Xiaowei Zhan, John M. Shelton, Jeffrey A. SoRelle, Katie Keller, Danielle Renee Lazaro, Eva Marie Y. Moresco, Jin Huk Choi, Bruce Beutler
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Distinct pathways and molecules may support embryonic versus postnatal thymic epithelial cell (TEC) development and maintenance. Here, we identify a mechanism by which TEC numbers and function are maintained postnatally. A viable missense al
Externí odkaz:
https://doaj.org/article/9bb9af5e62a640e19549ec5330ca64ad
Autor:
Ran Song, William McAlpine, Aaron M. Fond, Evan Nair-Gill, Jin Huk Choi, Elisabeth E. L. Nyström, Liisa Arike, Sydney Field, Xiaohong Li, Jeffrey A. SoRelle, James J. Moresco, Eva Marie Y. Moresco, John R. Yates, Parastoo Azadi, Josephine Ni, George M. H. Birchenough, Bruce Beutler, Emre E. Turer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract A key feature in intestinal immunity is the dynamic intestinal barrier, which separates the host from resident and pathogenic microbiota through a mucus gel impregnated with antimicrobial peptides. Using a forward genetic screen, we have fou
Externí odkaz:
https://doaj.org/article/c2c5a71364e54a7780fc6c6274ed1f2e
Autor:
Abhinav Thummala, Rhea Sudhakaran, Anoop Gurram, Jacqueline Mersch, Alexa Badalamenti, Garrett Gottaway, Jason Y. Park, Jeffrey A. Sorelle, Sukh Makhnoon
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101867- (2024)
Purpose: A primary challenge in clinical genetics is accurate interpretation of identified variants and relaying the information to patients and providers. Inconsistencies around handling variant reclassifications and notifying patients, combined wit
Externí odkaz:
https://doaj.org/article/d9bc88f3adf548ebba681344998acf47
Autor:
Zhao Zhang, Yu Xun, Shunxing Rong, Lijuan Yan, Jeffrey A. SoRelle, Xiaohong Li, Miao Tang, Katie Keller, Sara Ludwig, Eva Marie Y. Moresco, Bruce Beutler
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Obesity is a major risk factor for fatty liver disease. Here, using a forward genetic screen, the authors identify the gene GM4951 as a GTPase involved in lipid oxidation and development of NAFLD in mice.
Externí odkaz:
https://doaj.org/article/0fb5045a02d548e7bf3ceeaa615047a3
Autor:
Richard Lueking, Andrew E. Clark, Madhusudhanan Narasimhan, Lenin Mahimainathan, Alagarraju Muthukumar, Christian P. Larsen, Jeffrey A. SoRelle
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Immunocompromised patients can experience prolonged SARS-CoV-2 infections in the setting of a lack of protectivity immunity despite vaccination. As circulating SARS-CoV-2 strains become more heterogeneous, concomitant infection with multiple SARS-CoV
Externí odkaz:
https://doaj.org/article/93262ea8a7674c6a8a62b8fd35720f87
Autor:
Takeshi Itoh, Morihito Takita, Jeffrey A. Sorelle, Masayuki Shimoda, Koji Sugimoto, Daisuke Chujo, Huanying Qin, Bashoo Naziruddin, Marlon F. Levy M.D., F.A.C.S., Shinichi Matsumoto
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Establishing reliable islet potency assay is a critical and unmet issue for clinical islet transplantation. Recently, we reported that islets contained high levels of high mobility group box 1 (HMGB1) and damaged islets released HMGB1 in a mouse mode
Externí odkaz:
https://doaj.org/article/83a2287451b74de59161c2e6ecd9c95a
Autor:
Mitzi Aguilar, Hao Chen, Subhransu S. Sahoo, Wenxin Zheng, Jessica Grubman, Jeffrey A. SoRelle, Elena Lucas, Diego H. Castrillon
Publikováno v:
American Journal of Surgical Pathology. 47:618-629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357fb0c8fe3ed493faeea34a69f99f5d
https://doi.org/10.1097/pas.0000000000002034
https://doi.org/10.1097/pas.0000000000002034
Autor:
Srinivas Bollineni, Luke D. Mahan, Adrian Lawrence, John Joerns, Irina Timofte, Fernando Torres, Vaidehi Kaza, Ricardo M. La Hoz, Jeffrey A. SoRelle, Corey D. Kershaw, Lance S. Terada, Song Zhang, Manish R. Mohanka, Amit Banga
Publikováno v:
Transplantation Proceedings. 54:1517-1523
There are limited data regarding the clinical efficacy of COVID-19 vaccines among lung transplant (LT) patients.We included all LT patients diagnosed with COVID-19 between March 1, 2020, and December 10, 2021 (n = 84; median age 55, range, 20-73 year
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5726ac4847cf7d74297c0544d29e9b0e
https://doi.org/10.1016/j.transproceed.2022.05.030
https://doi.org/10.1016/j.transproceed.2022.05.030
Autor:
Andrew E Clark, Zhaohui Wang, Emily Ostman, Hui Zheng, Huiyu Yao, Brandi Cantarel, Mohammed Kanchwala, Chao Xing, Li Chen, Pei Irwin, Yan Xu, Dwight Oliver, Francesca M Lee, Jeffrey R Gagan, Laura Filkins, Alagarraju Muthukumar, Jason Y Park, Ravi Sarode, Jeffrey A SoRelle
Publikováno v:
Clinical Chemistry. 68:1042-1052
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerge, and effective tracking requires rapid return of results. Surveillance of variants is typically performed by whole genome sequencing (WGS), which can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5241befc998261d119564b3d879e4be1
https://doi.org/10.1093/clinchem/hvac081
https://doi.org/10.1093/clinchem/hvac081