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pro vyhledávání: '"Jeffrey A. Rotondo"'
Autor:
Andrew H. Kang, David D. Brand, John M. Stuart, David L. Cullins, Jeoung-Eun Park, Jeffrey A. Rotondo, Ae-Kyung Yi, Linda K. Myers
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 197(12)
Rheumatoid arthritis is an autoimmune disorder characterized by T cell dysregulation. We have shown that an altered peptide ligand (A9) activates T cells to use an alternate signaling pathway that is dependent on FcRγ and spleen tyrosine kinase, res
Autor:
Robert D. Schreiber, Jörn C. Albring, Harinder Singh, Leslie A. Weiss, Cora T. Aurthur, Samuel S. K. Lam, Elke Glasmacher, Nicole M. Kretzer, Michael S. Behnke, Wei Liao, Theresa L. Murphy, Xiaodi Wu, Ansuman T. Satpathy, Mona Mashayekhi, Wan-Ling Lee, Peng Li, Kenneth M. Murphy, L. David Sibley, Christina L. Stallings, Wumesh Kc, Roxane Tussiwand, Jeffrey A. Rotondo, Warren J. Leonard, Brian T. Edelson
Publikováno v:
Nature
The AP1 transcription factor Batf3 is required for homeostatic development of CD8α(+) classical dendritic cells that prime CD8 T-cell responses against intracellular pathogens. Here we identify an alternative, Batf3-independent pathway in mice for C