Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jeffrey A. Porter"'
Autor:
Xiaobo Ke, Kwontae You, Matthieu Pichaud, Henry J. Haiser, Daniel B. Graham, Hera Vlamakis, Jeffrey A. Porter, Ramnik J. Xavier
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background The endoplasmic reticulum (ER) is a membranous organelle that maintains proteostasis and cellular homeostasis, controlling the fine balance between health and disease. Dysregulation of the ER stress response has been implicated in
Externí odkaz:
https://doaj.org/article/22ecbd718a54456084a19bcfe9406fc4
Autor:
Ralph Tiedt, Alan Buckler, Christopher J. Wilson, Diana Graus-Porta, Vic E. Myer, Jeffrey A. Porter, William R. Sellers, Francesco Hofmann, Peter M. Finan, Thomas Metz, Vito Guagnano, Chris X. Lu, Feng He, Yao Yao, Christian Chatenay-Rivauday, Andreas Buness, Christelle Stamm, Sabrina Wagner, Kelly Ann Sheppard, Lijuan Liu, Douglas Jeffery, Sneha Sanghavi, Vanessa J. Craig, Fred Harbinski
PDF file - 75K, This file contains detailed descriptions of materials and methods that had to be omitted from the main manuscript due to space limitations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c98b6b1a6e0d1506dc7ac17ab9bf49
https://doi.org/10.1158/2159-8290.22528515.v1
https://doi.org/10.1158/2159-8290.22528515.v1
Autor:
Ralph Tiedt, Alan Buckler, Christopher J. Wilson, Diana Graus-Porta, Vic E. Myer, Jeffrey A. Porter, William R. Sellers, Francesco Hofmann, Peter M. Finan, Thomas Metz, Vito Guagnano, Chris X. Lu, Feng He, Yao Yao, Christian Chatenay-Rivauday, Andreas Buness, Christelle Stamm, Sabrina Wagner, Kelly Ann Sheppard, Lijuan Liu, Douglas Jeffery, Sneha Sanghavi, Vanessa J. Craig, Fred Harbinski
PDF file - 59K, This file contains additional experimental data relating to the profile of JAA120, secretome screening results, gene expression data, and in vivo MET/FGR inhibitor synergy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8822d966da43dd533bf0e796b84a95c8
https://doi.org/10.1158/2159-8290.22528509
https://doi.org/10.1158/2159-8290.22528509
Autor:
Ralph Tiedt, Alan Buckler, Christopher J. Wilson, Diana Graus-Porta, Vic E. Myer, Jeffrey A. Porter, William R. Sellers, Francesco Hofmann, Peter M. Finan, Thomas Metz, Vito Guagnano, Chris X. Lu, Feng He, Yao Yao, Christian Chatenay-Rivauday, Andreas Buness, Christelle Stamm, Sabrina Wagner, Kelly Ann Sheppard, Lijuan Liu, Douglas Jeffery, Sneha Sanghavi, Vanessa J. Craig, Fred Harbinski
PDF file - 310K, This file contains additional experimental data relating to ligand-mediated rescue and drug combinations in cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6056ab23a9ee72d9ae3c3a8094ae846e
https://doi.org/10.1158/2159-8290.22528518
https://doi.org/10.1158/2159-8290.22528518
Autor:
Ralph Tiedt, Alan Buckler, Christopher J. Wilson, Diana Graus-Porta, Vic E. Myer, Jeffrey A. Porter, William R. Sellers, Francesco Hofmann, Peter M. Finan, Thomas Metz, Vito Guagnano, Chris X. Lu, Feng He, Yao Yao, Christian Chatenay-Rivauday, Andreas Buness, Christelle Stamm, Sabrina Wagner, Kelly Ann Sheppard, Lijuan Liu, Douglas Jeffery, Sneha Sanghavi, Vanessa J. Craig, Fred Harbinski
XLS file - 147K, Expression of selected RTKs and cognate ligands in cancer cell lines as a basis for selecting models for testing of FGFR/MET inhibitor combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356e72ceed31e9513e886aea92daa0c2
https://doi.org/10.1158/2159-8290.22528512
https://doi.org/10.1158/2159-8290.22528512
Autor:
Daniel B. Graham, Henry J. Haiser, Kwontae You, Ramnik J. Xavier, Jeffrey A. Porter, Matthieu Pichaud, Xiaobo Ke, Hera Vlamakis
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-17 (2021)
Genome Biology
Genome Biology
BackgroundThe endoplasmic reticulum (ER) is a membranous organelle that maintains proteostasis and cellular homeostasis, controlling the fine balance between health and disease. Dysregulation of the ER stress response has been implicated in intestina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d90b83c7f7b6496d0f07f85fb881485
https://doaj.org/article/22ecbd718a54456084a19bcfe9406fc4
https://doaj.org/article/22ecbd718a54456084a19bcfe9406fc4
Autor:
Andrew C. Tolonen, Nadine Fornelos, John W. Annand, Ashley L. Garner, R. Balfour Sartor, Jason Bishai, Hera Vlamakis, Eric A. Franzosa, Clary B. Clish, Jeffrey A. Porter, Julian Avila-Pacheco, Henry J. Haiser, Akihiko Oka, Curtis Huttenhower, Timothy D. Arthur, Jason Lloyd-Price, Ramnik J. Xavier
Publikováno v:
Nature microbiology
Inflammatory bowel diseases (IBD) are associated with alterations in gut microbial abundances and lumenal metabolite concentrations, but the effects of specific metabolites on the gut microbiota in health and disease remain largely unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2da18bbcffabeafc6b7c8562a52896
https://doi.org/10.1038/s41564-019-0655-7
https://doi.org/10.1038/s41564-019-0655-7
Autor:
Sabine Rudolf, Natalya Dorshakova, Edward J. Oakeley, Andrew Brantley Hall, Raivo Uibo, Juhi Somani, Timothy D. Arthur, Henry J. Haiser, Raivo Kolde, Vallo Tillmann, Moran Yassour, Jorma Ilonen, Damian R. Plichta, Suvi M. Virtanen, Ramnik J. Xavier, Heli Siljander, Hera Vlamakis, Mikael Knip, Alice C. McHardy, Harri Lähdesmäki, Xiaobo Ke, Curtis Huttenhower, Jeffrey A. Porter, Rachel A. Young, Kristiina Luopajärvi, Philipp C. Münch, Sergei Mokurov, Tommi Vatanen
Publikováno v:
Nature microbiology
The human gut microbiome matures towards the adult composition during the first years of life and is implicated in early immune development. Here, we investigate the effects of microbial genomic diversity on gut microbiome development using integrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa89c712904c24ebb6d39227d81a847
https://doi.org/10.1038/s41564-018-0321-5
https://doi.org/10.1038/s41564-018-0321-5
Autor:
Guadalupe J. Jasso, Alok Jaiswal, Mukund Varma, Tyler Laszewski, Angelo Grauel, Abdifatah Omar, Nilsa Silva, Glenn Dranoff, Jeffrey A. Porter, Keith Mansfield, Viviana Cremasco, Aviv Regev, Ramnik J. Xavier, Daniel B. Graham
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001532 (2022)
Chronic inflammation is often associated with the development of tissue fibrosis, but how mesenchymal cell responses dictate pathological fibrosis versus resolution and healing remains unclear. Defining stromal heterogeneity and identifying molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b58e046763f0ebb7c670c83a56d69d3
https://doi.org/10.1371/journal.pbio.3001532
https://doi.org/10.1371/journal.pbio.3001532
Autor:
Jeffrey A. Porter, Hera Vlamakis, A. Brantley Hall, Zachary A. Costliow, Michael A. Durney, Emily R. Temple, Damian R. Plichta, Hugo Arellano-Santoyo, Xiebin Gu, Eric M. Brown, Matthieu Pichaud, Kai Liu, Clary A. Clish, Ramnik J. Xavier
Publikováno v:
Cell Host & Microbe. 29:1351-1365.e11
Summary Bacterial ADP-ribosyltransferases (ADPRTs) have been described as toxins involved in pathogenesis through the modification of host proteins. Here, we report that ADPRTs are not pathogen restricted but widely prevalent in the human gut microbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362826bcdeb62648cdad12ac3a3934c8
https://doi.org/10.1016/j.chom.2021.07.011
https://doi.org/10.1016/j.chom.2021.07.011