Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jeffrey A. Melvin"'
Autor:
Grace P. Carreno-Florez, Brian R. Kocak, Matthew R. Hendricks, Jeffrey A. Melvin, Katrina B. Mar, Jessica Kosanovich, Rachel L. Cumberland, Greg M. Delgoffe, Sruti Shiva, Kerry M. Empey, John W. Schoggins, Jennifer M. Bomberger
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/27a20c8a04344fb7b4939fe6ea404259
Autor:
Allison L. Haas, Anna C. Zemke, Jeffrey A. Melvin, Catherine R. Armbruster, Matthew R. Hendricks, John Moore, Seyed Mehdi Nouraie, Patrick H. Thibodeau, Stella E. Lee, Jennifer M. Bomberger
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112270- (2023)
Summary: The cystic fibrosis (CF) respiratory tract harbors pathogenic bacteria that cause life-threatening chronic infections. Of these, Pseudomonas aeruginosa becomes increasingly dominant with age and is associated with worsening lung function and
Externí odkaz:
https://doaj.org/article/d50ebee9b83744a1b83baf06756823ac
Autor:
Catherine R. Armbruster, Kelvin Li, Megan R. Kiedrowski, Anna C. Zemke, Jeffrey A. Melvin, John Moore, Samar Atteih, Adam C. Fitch, Matthew DuPont, Christopher D. Manko, Madison L. Weaver, Jordon R. Gaston, John F. Alcorn, Alison Morris, Barbara A. Methé, Stella E. Lee, Jennifer M. Bomberger
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Chronic rhinosinusitis (CRS) is a common, yet underreported and understudied manifestation of upper respiratory disease in people with cystic fibrosis (CF). Recently developed standard of care guidelines for the management of CF CRS suggest
Externí odkaz:
https://doaj.org/article/7a2bc36f5e39472e9ab36c7cf0ad33b9
Autor:
Catherine R. Armbruster, Christopher W. Marshall, Arkadiy I. Garber, Jeffrey A. Melvin, Anna C. Zemke, John Moore, Paula F. Zamora, Kelvin Li, Ian L. Fritz, Christopher D. Manko, Madison L. Weaver, Jordan R. Gaston, Alison Morris, Barbara Methé, William H. DePas, Stella E. Lee, Vaughn S. Cooper, Jennifer M. Bomberger
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109829- (2021)
Summary: Pseudomonas aeruginosa notoriously adapts to the airways of people with cystic fibrosis (CF), yet how infection-site biogeography and associated evolutionary processes vary as lifelong infections progress remains unclear. Here we test the hy
Externí odkaz:
https://doaj.org/article/49c55f56b39949d0b3f4fb82ffc0cac2
Autor:
Daniel M. Cornforth, Frances L. Diggle, Jeffrey A. Melvin, Jennifer M. Bomberger, Marvin Whiteley
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Laboratory models are a cornerstone of modern microbiology, but the accuracy of these models has not been systematically evaluated. As a result, researchers often choose models based on intuition or incomplete data. We propose a general quan
Externí odkaz:
https://doaj.org/article/fc699cfcf8404da5a9ed7966015b5d96
Autor:
Jeffrey A. Melvin, Jordan R. Gaston, Shawn N. Phillips, Michael J. Springer, Christopher W. Marshall, Robert M. Q. Shanks, Jennifer M. Bomberger
Publikováno v:
mSphere, Vol 2, Iss 6 (2017)
ABSTRACT Microorganisms exist in a diverse ecosystem and have evolved many different mechanisms for sensing and influencing the polymicrobial environment around them, utilizing both diffusible and contact-dependent signals. Contact-dependent growth i
Externí odkaz:
https://doaj.org/article/665f0074282246ea9272cfe4007bc250
Autor:
Jeffrey A. Melvin, Lauren P. Lashua, Megan R. Kiedrowski, Guanyi Yang, Berthony Deslouches, Ronald C. Montelaro, Jennifer M. Bomberger
Publikováno v:
mSphere, Vol 1, Iss 3 (2016)
ABSTRACT Antimicrobial-resistant infections are an urgent public health threat, and development of novel antimicrobial therapies has been painstakingly slow. Polymicrobial infections are increasingly recognized as a significant source of severe disea
Externí odkaz:
https://doaj.org/article/60146e0eeb594e39abdaf580efee2efc
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
ABSTRACT Bordetella filamentous hemagglutinin (FHA), a primary component of acellular pertussis vaccines, contributes to virulence, but how it functions mechanistically is unclear. FHA is first synthesized as an ~370-kDa preproprotein called FhaB. Re
Externí odkaz:
https://doaj.org/article/abdb820fc385442cb40926f0005786cc
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT Bordetella fimbriae (FIM) are generally considered to function as adhesins despite a lack of experimental evidence supporting this conclusion for Bordetella pertussis and evidence against a requirement for FIM in adherence of Bordetella bron
Externí odkaz:
https://doaj.org/article/4f43bdadfb4c4501b0bdc75328f3a54b
Autor:
Jennifer M. Bomberger, Christopher W. Marshall, S. Lee, Vaughn S. Cooper, Jeffrey A. Melvin, Paula F. Zamora, John A. Moore, William H. DePas, Catherine R. Armbruster, Arkadiy I. Garber, Anna C. Zemke
Publikováno v:
Journal of Cystic Fibrosis. 20:S192-S193