Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Jeffrey A. Kraut"'
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 4, Pp 149-155 (2023)
Abstract Acidification of the cellular lysosome is an important factor in infection of mammalian cells by SARS‐CoV‐2. Therefore, raising the pH of the lysosome would theoretically be beneficial in prevention or treatment of SARS‐CoV‐2 infecti
Externí odkaz:
https://doaj.org/article/5530ce4269a24c89af40458cd0c4d7fb
Autor:
Glenn T. Nagami, Jeffrey A. Kraut
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2420 (2024)
Systemic acid–base status is primarily determined by the interplay of net acid production (NEAP) arising from metabolism of ingested food stuffs, buffering of NEAP in tissues, generation of bicarbonate by the kidney, and capture of any bicarbonate
Externí odkaz:
https://doaj.org/article/bbc5508e183041a1b73245dd9a33146e
Autor:
Michael E. Mullins, Jeffrey A. Kraut
Publikováno v:
African Journal of Emergency Medicine, Vol 11, Iss 2, Pp 263- (2021)
Externí odkaz:
https://doaj.org/article/c5b87a5dba7f45998bb9a8e142dc5bee
Publikováno v:
FASEB BioAdvances. 5:149-155
Autor:
Victoria Murray, Ekamol Tantisattamo, Connie M. Rhee, Jeffrey A. Kraut, Melissa Soohoo, Christina J. Catabay, Yoshitsugu Obi, Carola-Ellen Kleine, Christina Park, Kamyar Kalantar-Zadeh, Jui-Ting Hsiung, Cachet Wenziger, Csaba P. Kovesdy, Yuji Lee, Elani Streja
Publikováno v:
Am J Nephrol
Background: Serum bicarbonate or total carbon dioxide (CO2) concentrations decline as chronic kidney disease (CKD) progresses and rise after dialysis initiation. While metabolic acidosis accelerates the progression of CKD and is associated with highe
Autor:
Glenn T. Nagami, Jeffrey A. Kraut
Publikováno v:
Advances in chronic kidney disease. 29(4)
Normallly the kidneys handle the daily acid load arising from net endogenous acid production from the metabolism of ingested animal protein (acid) and vegetables (base). With chronic kidney disease, reduced acid excretion by the kidneys is primarily
Autor:
Jeffrey A. Kraut, Kalani L. Raphael
Publikováno v:
Clin J Am Soc Nephrol
Maintenance of normal blood pH is critical for cellular function. Yet, blood pH is uncommonly measured in the outpatient setting. Instead, serum [total CO2] ([TCO2]) is used to screen for acid-base disturbances, the argument being that both metabolic
Autor:
Nicolaos E. Madias, Jeffrey A. Kraut
Publikováno v:
American Journal of Kidney Diseases. 73:572-575
Autor:
Michael E. Mullins, Jeffrey A. Kraut
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 79(6)
Poisoning is a common problem in the United States. Acid-base disturbances, electrolyte derangements, or acute kidney injury result from severe poisoning from toxic alcohols, salicylates, metformin, and acetaminophen. Lithium is highly sensitive to s
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53932 (2013)
INTRODUCTION: Acute metabolic acidosis impairs cardiovascular function and increases the mortality of critically ill patients. However, the precise mechanism(s) underlying these effects remain unclear. We hypothesized that targeting pH-regulatory pro
Externí odkaz:
https://doaj.org/article/a06c57cc99a943f8b80cd1fd44c02de0