Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Jeffrey A. Greenwood"'
Autor:
Andrew M Hau, Jeffrey A Greenwood, Christiane V Löhr, Jeffrey D Serrill, Philip J Proteau, Ian G Ganley, Kerry L McPhail, Jane E Ishmael
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65250 (2013)
Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cance
Externí odkaz:
https://doaj.org/article/ad6d170e6dbe49d98aa2c9990206bcf2
Autor:
E Scott Graham, Kerhan K Woo, Miranda Aalderink, Sandie Fry, Jeffrey M Greenwood, Michelle Glass, Mike Dragunow
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72011 (2013)
HEK293 cells have been used extensively to generate stable cell lines to study G protein-coupled receptors, such as muscarinic acetylcholine receptors (mAChRs). The activation of M1 mAChRs in various cell types in vitro has been shown to be protectiv
Externí odkaz:
https://doaj.org/article/b5d068d9909949768e81ab33fea29383
Autor:
James E. Hutchison, Vihangi Hindagolla, Hagai Abeliovich, Matthew G. Boenzli, Jun Ding, Alan T. Bakalinsky, John M. Miller, Mark R. Smith, Jeffrey A. Greenwood
Publikováno v:
Applied and Environmental Microbiology. 79:728-733
Positively charged gold nanoparticles (0.8-nm core diameter) reduced yeast survival, but not growth, at a concentration of 10 to 100 μg/ml. Among 17 resistant deletion mutants isolated in a genome-wide screen, highly significant enrichment was obser
Publikováno v:
Current Topics in Medicinal Chemistry. 11:1811-1820
Kiwifruit are nutrient-dense fruit with a reputation for promoting good health. Although this could be attributed to the high vitamin C content of kiwifruit, other phytochemicals could also provide health benefits. Kiwifruit are commonly reported to
Publikováno v:
Molecular Pharmacology. 70:860-868
Phospholipase C-beta (PLC-beta) isoenzymes are key effectors in G protein-coupled signaling pathways. Prior research suggests that some isoforms of PLC-beta may exist and function as dimers. Using coimmunoprecipitation assays of differentially tagged
Autor:
Jeffrey M. Greenwood, Simon J. O'Carroll, Rachel Cameron, Hannah M. Gibbons, Mike Dragunow, Andree G. Pearson, Pritika Narayan
Publikováno v:
Neuroscience. 140:1149-1156
Valproic acid is widely used for the treatment of epilepsy and mood disorders, but its mode of action is unclear. Treatment of neuronal cells with valproic acid promotes neurite sprouting, is neuroprotective and drives neurogenesis; however its effec
Autor:
Jeffrey A. Greenwood, Tamara S. Fraley, Corey Ayne Singleton, Clifford B. Pereira, Thuan C. Tran
Publikováno v:
Journal of Biological Chemistry. 280:15479-15482
The active association-dissociation of dynamic protein-protein interactions is critical for the ability of the actin cytoskeleton to remodel. To determine the influence of phosphoinositide binding on the dynamic interaction of α-actinin with actin f
Autor:
Jeffrey M. Greenwood, Mike Dragunow
Publikováno v:
Journal of Neurochemistry. 82:389-397
This study describes the effect of signalling through muscarinic acetylcholine receptors on two transcription factors implicated in long-term synaptic plasticity and memory formation, EGR1 and the cyclic AMP response element binding protein (CREB). I
Publikováno v:
Journal of Cell Biology. 150:627-642
Focal adhesions are an elaborate network of interconnecting proteins linking actin stress fibers to the extracellular matrix substrate. Modulation of the focal adhesion plaque provides a mechanism for the regulation of cellular adhesive strength. Usi
Publikováno v:
Microscopy Research and Technique. 43:420-432
Adhesion is a process that can be divided into three separate stages: (1) cell attachment, (2) cell spreading, and (3) the formation of focal adhesions and stress fibers. With each stage the adhesive strength of the cell increases. De-adhesion can be