Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Jeffrey A. Gorman"'
Autor:
Richard J. Lobb, Kekoolani S. Visan, Li-Ying Wu, Emma L. Norris, Marcus L. Hastie, Sarah Everitt, Ian A. Yang, Rayleen V. Bowman, Shankar Siva, Jill E. Larsen, Jeffrey J. Gorman, Michael MacManus, Antoine Leimgruber, Kwun M. Fong, Andreas Möller
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
EMT-induced protein changes in small extracellular vesicles are detectable in NSCLC patients and have prognostic significance.
Externí odkaz:
https://doaj.org/article/6f38214ed06645a1a1e34af0b67470e7
Autor:
Lakmali Munasinghage Silva, Thomas Stoll, Thomas Kryza, Carson Ryan Stephens, Marcus Lachlan Hastie, Helen Frances Irving-Rodgers, Ying Dong, Jeffrey John Gorman, Judith Ann Clements
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The cleavage preferences of Kallikrein-related peptidase 7 (KLK7) have previously been delineated using synthetic peptide libraries of fixed length, or single protein chains and have suggested that KLK7 exerts a chymotryptic-like cleavage pr
Externí odkaz:
https://doaj.org/article/0ce0071cd33d4881b0d18b43301cfac5
Autor:
Cassandra L. Pegg, Leanne T. Cooper, Jing Zhao, Michael Gerometta, Fiona M. Smith, Michael Yeh, Perry F. Bartlett, Jeffrey J. Gorman, Andrew W. Boyd
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Eph receptors have emerged as targets for therapy in both neoplastic and non-neoplastic disease, however, particularly in non-neoplastic diseases, redundancy of function limits the effectiveness of targeting individual Eph proteins. We have
Externí odkaz:
https://doaj.org/article/8eef0bce7cd74492b8bf629ada41ee50
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Plant pathogens secrete effector molecules that suppress the plant immune response to facilitate disease development. AvrPto is a well-studied effector from the phytopathogenic bacterium Pseudomonas syringae. Here we utilize an in planta proximity de
Externí odkaz:
https://doaj.org/article/5899620855c143db9ef217e44f4eae4a
Autor:
Jonathan P. Anderson, James K. Hane, Thomas Stoll, Nicholas Pain, Marcus L. Hastie, Parwinder Kaur, Christine Hoogland, Jeffrey J. Gorman, Karam B. Singh
Publikováno v:
Data in Brief, Vol 8, Iss , Pp 267-271 (2016)
Rhizoctonia solani is an important root infecting pathogen of a range of food staples worldwide including wheat, rice, maize, soybean, potato, legumes and others. Conventional resistance breeding strategies are hindered by the absence of tractable ge
Externí odkaz:
https://doaj.org/article/24e7b4d54cae4aab83eee115fc520a16
Autor:
Robert A Syme, Kar-Chun Tan, James K Hane, Kejal Dodhia, Thomas Stoll, Marcus Hastie, Eiko Furuki, Simon R Ellwood, Angela H Williams, Yew-Foon Tan, Alison C Testa, Jeffrey J Gorman, Richard P Oliver
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147221 (2016)
Parastagonospora nodorum, the causal agent of Septoria nodorum blotch (SNB), is an economically important pathogen of wheat (Triticum spp.), and a model for the study of necrotrophic pathology and genome evolution. The reference P. nodorum strain SN1
Externí odkaz:
https://doaj.org/article/4785b17b35234ec4b65e999f1d06018d
Autor:
Katarina Luko, Pritisha Rozario, Lin-Fa Wang, H. Benjamin Larman, Benjamin Py H. Lee, Stephen J. Elledge, Ian H. Mendenhall, Shailendra Mani, Jeffrey J. Gorman, Marcus L. Hastie, Pui San Kong, Aaron T. Irving, Gavin J. D. Smith, Wan Ni Chia
Publikováno v:
Cellular and Molecular Life Sciences. 77:1607-1622
Natural reservoir hosts can sustain infection of pathogens without succumbing to overt disease. Multiple bat species host a plethora of viruses, pathogenic to other mammals, without clinical symptoms. Here, we detail infection of bat primary cells, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d405a572d5b9dd8a59ef361d76b81d
https://doi.org/10.1007/s00018-019-03242-x
https://doi.org/10.1007/s00018-019-03242-x
Autor:
Jude M. Przyborski, Tina S. Skinner-Adams, Paul R. Gilson, Jessica A. Engel, Jeffrey J. Gorman, Madeleine J. Headlam, Gregory L. Blatch, Addmore Shonhai, Emma L. Norris, Katherine T. Andrews
Publikováno v:
Experimental Parasitology. 198:7-16
Plasmodium falciparum histone deacetylases (PfHDACs) are an important class of epigenetic regulators that alter protein lysine acetylation, contributing to regulation of gene expression and normal parasite growth and development. PfHDACs are therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce0289e9fc0b711cd74b010be7e4ffb
https://doi.org/10.1016/j.exppara.2019.01.008
https://doi.org/10.1016/j.exppara.2019.01.008
Autor:
Monika Köhnke, Christine Delon, Marcus L Hastie, Uyen T T Nguyen, Yao-Wen Wu, Herbert Waldmann, Roger S Goody, Jeffrey J Gorman, Kirill Alexandrov
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81758 (2013)
Protein prenylation is a widespread post-translational modification in eukaryotes that plays a crucial role in membrane targeting and signal transduction. RabGTPases is the largest group of post-translationally C-terminally geranylgeranylated. All Ra
Externí odkaz:
https://doaj.org/article/dc24756c647a4436b65d4a1980908b6b
Autor:
Brian J Morrison, Marcus L Hastie, Yadveer S Grewal, Zara C Bruce, Chris Schmidt, Brent A Reynolds, Jeffrey J Gorman, J Alejandro Lopez
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52692 (2012)
Breast cancer is a heterogeneous disease, composed of tumour cells with differing gene expressions and phenotypes. Very few antigens have been identified and a better understanding of tumour initiating-cells as targets for therapy is critically neede
Externí odkaz:
https://doaj.org/article/c1808a08c1a846319bc6fa35add54b9d